piperacillin-3845 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the piperacillin-3845 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACPP acid phosphatase, prostate
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
AKT3 v-akt murine thymoma viral oncogene homolog 3
APAF1 apoptotic peptidase activating factor 1
ARNT aryl hydrocarbon receptor nuclear translocator
ARSD arylsulfatase D
BMP10 bone morphogenetic protein 10
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1ORF61 chromosome 1 open reading frame 61
CA9 carbonic anhydrase IX
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC25A cell division cycle 25A
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLIP4 CAP-GLY domain containing linker protein family, member 4
DAPK3 death-associated protein kinase 3
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOCK5 dedicator of cytokinesis 5
DSC2 desmocollin 2
DUSP6 dual specificity phosphatase 6
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EML2 echinoderm microtubule associated protein like 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHA3 EPH receptor A3
EZR ezrin
G6PC2 glucose-6-phosphatase, catalytic, 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HFE hemochromatosis
HN1L hematological and neurological expressed 1-like
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IL17RC interleukin 17 receptor C
IL23A interleukin 23, alpha subunit p19
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLF9 Kruppel-like factor 9
KMT2A lysine (K)-specific methyltransferase 2A
KRT19P2 keratin 19 pseudogene 2
KRT6B keratin 6B, type II
MAGEB2 melanoma antigen family B2
MAP2K7 mitogen-activated protein kinase kinase 7
MCM3AP minichromosome maintenance complex component 3 associated protein
MEGF6 multiple EGF-like-domains 6
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRC2 mannose receptor, C type 2
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD1 neuronal differentiation 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NUMA1 nuclear mitotic apparatus protein 1
NUP188 nucleoporin 188kDa
PICK1 protein interacting with PRKCA 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PPIA peptidylprolyl isomerase A (cyclophilin A)
PSAT1 phosphoserine aminotransferase 1
PTPRA protein tyrosine phosphatase, receptor type, A
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB40A RAB40A, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RB1 retinoblastoma 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPN sialophorin
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TBX5 T-box 5
TCF3 transcription factor 3
TICAM1 toll-like receptor adaptor molecule 1
TMOD2 tropomodulin 2 (neuronal)
TMSB4Y thymosin beta 4, Y-linked
TROVE2 TROVE domain family, member 2
TSC22D2 TSC22 domain family, member 2
TWF1 twinfilin actin binding protein 1
UCN urocortin
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
WDR55 WD repeat domain 55
WSB1 WD repeat and SOCS box containing 1
WTAP Wilms tumor 1 associated protein
ZBTB43 zinc finger and BTB domain containing 43
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZNF506 zinc finger protein 506
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
AMH anti-Mullerian hormone
ANKH ANKH inorganic pyrophosphate transport regulator
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD3A ATPase family, AAA domain containing 3A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C11ORF21 chromosome 11 open reading frame 21
C1ORF35 chromosome 1 open reading frame 35
C4BPA complement component 4 binding protein, alpha
C5 complement component 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC68 coiled-coil domain containing 68
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSTA cystatin A (stefin A)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXADR coxsackie virus and adenovirus receptor
DGAT1 diacylglycerol O-acyltransferase 1
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHB6 EPH receptor B6
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF4 fibroblast growth factor 4
FGL1 fibrinogen-like 1
GAB2 GRB2-associated binding protein 2
GPNMB glycoprotein (transmembrane) nmb
GPR19 G protein-coupled receptor 19
HCAR3 hydroxycarboxylic acid receptor 3
HDAC5 histone deacetylase 5
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HOXC10 homeobox C10
INPP1 inositol polyphosphate-1-phosphatase
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KREMEN2 kringle containing transmembrane protein 2
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LRP3 low density lipoprotein receptor-related protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MRPL52 mitochondrial ribosomal protein L52
MTA2 metastasis associated 1 family, member 2
MYO1F myosin IF
NME5 NME/NM23 family member 5
OLFML2A olfactomedin-like 2A
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI3 peptidyl arginine deiminase, type III
PCDHB13 protocadherin beta 13
PORCN porcupine homolog (Drosophila)
PRPH peripherin
RAB3A RAB3A, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RIN1 Ras and Rab interactor 1
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGCE sarcoglycan, epsilon
SKI SKI proto-oncogene
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPON2 spondin 2, extracellular matrix protein
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAB2 stabilin 2
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBL1Y transducin (beta)-like 1, Y-linked
TCP10 t-complex 10
TESC tescalcin
TFF2 trefoil factor 2
TGFBR1 transforming growth factor, beta receptor 1
TLN1 talin 1
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TOR4A torsin family 4, member A
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
TUBA4B tubulin, alpha 4b
UPP1 uridine phosphorylase 1
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF134 zinc finger protein 134
ZNF204P zinc finger protein 204, pseudogene
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF804A zinc finger protein 804A
ZSCAN2 zinc finger and SCAN domain containing 2