piperacillin-3939 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the piperacillin-3939 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP11A ATPase, class VI, type 11A
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
C1ORF95 chromosome 1 open reading frame 95
C1QL1 complement component 1, q subcomponent-like 1
C8B complement component 8, beta polypeptide
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCKBR cholecystokinin B receptor
CD177 CD177 molecule
CD6 CD6 molecule
CD70 CD70 molecule
CD8A CD8a molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP290 centrosomal protein 290kDa
CERS4 ceramide synthase 4
COL3A1 collagen, type III, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRYGC crystallin, gamma C
CYB5A cytochrome b5 type A (microsomal)
DCHS1 dachsous cadherin-related 1
DFNB31 deafness, autosomal recessive 31
DGKG diacylglycerol kinase, gamma 90kDa
DPF1 D4, zinc and double PHD fingers family 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ERCC2 excision repair cross-complementation group 2
FAM65B family with sequence similarity 65, member B
FBLN1 fibulin 1
FCAR Fc fragment of IgA receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKRP fukutin related protein
FN1 fibronectin 1
FRMD8 FERM domain containing 8
GP2 glycoprotein 2 (zymogen granule membrane)
GRAMD1B GRAM domain containing 1B
ICOSLG inducible T-cell co-stimulator ligand
IL17RC interleukin 17 receptor C
IL1RN interleukin 1 receptor antagonist
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITSN2 intersectin 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC75B leucine rich repeat containing 75B
MARK1 MAP/microtubule affinity-regulating kinase 1
MFSD6 major facilitator superfamily domain containing 6
MORN1 MORN repeat containing 1
MST1R macrophage stimulating 1 receptor
MUC13 mucin 13, cell surface associated
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP50 nucleoporin 50kDa
NYNRIN NYN domain and retroviral integrase containing
PAPPA2 pappalysin 2
PER1 period circadian clock 1
PGAP3 post-GPI attachment to proteins 3
PGLYRP1 peptidoglycan recognition protein 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PHOX2A paired-like homeobox 2a
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PQBP1 polyglutamine binding protein 1
PRTN3 proteinase 3
PTAFR platelet-activating factor receptor
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS2 RNA binding motif, single stranded interacting protein 2
RBP4 retinol binding protein 4, plasma
RGS14 regulator of G-protein signaling 14
RGSL1 regulator of G-protein signaling like 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RUNX1 runt-related transcription factor 1
SERHL2 serine hydrolase-like 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLIT1 slit homolog 1 (Drosophila)
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPON1 spondin 1, extracellular matrix protein
SPRY4 sprouty homolog 4 (Drosophila)
SSTR2 somatostatin receptor 2
STIM1 stromal interaction molecule 1
STOML1 stomatin (EPB72)-like 1
SYNDIG1 synapse differentiation inducing 1
SYNE1 spectrin repeat containing, nuclear envelope 1
T T, brachyury homolog (mouse)
TDRD12 tudor domain containing 12
THAP3 THAP domain containing, apoptosis associated protein 3
THY1 Thy-1 cell surface antigen
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
UBA6 ubiquitin-like modifier activating enzyme 6
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACPP acid phosphatase, prostate
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY7 adenylate cyclase 7
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMPD1 adenosine monophosphate deaminase 1
ANXA2P1 annexin A2 pseudogene 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C11ORF21 chromosome 11 open reading frame 21
C1QB complement component 1, q subcomponent, B chain
C1QTNF3 C1q and tumor necrosis factor related protein 3
CARTPT CART prepropeptide
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
CIDEB cell death-inducing DFFA-like effector b
CTRL chymotrypsin-like
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
EDAR ectodysplasin A receptor
EMID1 EMI domain containing 1
ETV6 ets variant 6
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FSTL1 follistatin-like 1
GAB1 GRB2-associated binding protein 1
GCGR glucagon receptor
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPR3 G protein-coupled receptor 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSAP gamma-secretase activating protein
H2AFY2 H2A histone family, member Y2
HIST1H2AI histone cluster 1, H2ai
HIST1H4A histone cluster 1, H4a
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI35 interferon-induced protein 35
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT54 intraflagellar transport 54
IL2RG interleukin 2 receptor, gamma
IPO8 importin 8
IRF7 interferon regulatory factor 7
ITGA8 integrin, alpha 8
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL29 kelch-like family member 29
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMO7 LIM domain 7
LOC729164 hCG1732469
MAOB monoamine oxidase B
MSI1 musashi RNA-binding protein 1
NLGN1 neuroligin 1
NOTCH4 notch 4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PADI1 peptidyl arginine deiminase, type I
PADI3 peptidyl arginine deiminase, type III
PCDH17 protocadherin 17
PDE12 phosphodiesterase 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRKG2 protein kinase, cGMP-dependent, type II
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRM protein tyrosine phosphatase, receptor type, M
PYHIN1 pyrin and HIN domain family, member 1
RAB40AL RAB40A, member RAS oncogene family-like
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
SAA4 serum amyloid A4, constitutive
SELL selectin L
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETBP1 SET binding protein 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMR3A submaxillary gland androgen regulated protein 3A
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR5 toll-like receptor 5
TM4SF4 transmembrane 4 L six family member 4
TM4SF5 transmembrane 4 L six family member 5
TSC22D4 TSC22 domain family, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
USP19 ubiquitin specific peptidase 19
WDR62 WD repeat domain 62
XDH xanthine dehydrogenase
ZBED4 zinc finger, BED-type containing 4
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF35 zinc finger protein 35
ZNF484 zinc finger protein 484
ZNF682 zinc finger protein 682
ZW10 zw10 kinetochore protein
ZXDB zinc finger, X-linked, duplicated B