| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the piperacillin-4320 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| AEN | apoptosis enhancing nuclease |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARSD | arylsulfatase D |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP11A | ATPase, class VI, type 11A |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| COL7A1 | collagen, type VII, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CPZ | carboxypeptidase Z |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DICER1 | dicer 1, ribonuclease type III |
| DTNB | dystrobrevin, beta |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ENO3 | enolase 3 (beta, muscle) |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FGF4 | fibroblast growth factor 4 |
| FHL3 | four and a half LIM domains 3 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GPR157 | G protein-coupled receptor 157 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIST1H3E | histone cluster 1, H3e |
| HPX | hemopexin |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 |
| IL36G | interleukin 36, gamma |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1467 | KIAA1467 |
| LBX1 | ladybird homeobox 1 |
| LTB4R | leukotriene B4 receptor |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MED25 | mediator complex subunit 25 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| NDRG4 | NDRG family member 4 |
| NEK3 | NIMA-related kinase 3 |
| NEUROD6 | neuronal differentiation 6 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPEPL1 | aminopeptidase-like 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OPRL1 | opiate receptor-like 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHOX2A | paired-like homeobox 2a |
| PIDD1 | p53-induced death domain protein 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCB2 | phospholipase C, beta 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| POLM | polymerase (DNA directed), mu |
| PON1 | paraoxonase 1 |
| PRKCA | protein kinase C, alpha |
| PTAFR | platelet-activating factor receptor |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL7 | ribosomal protein L7 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SAFB2 | scaffold attachment factor B2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TJP3 | tight junction protein 3 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNPO2 | transportin 2 |
| TP63 | tumor protein p63 |
| TP73-AS1 | TP73 antisense RNA 1 |
| TPP1 | tripeptidyl peptidase I |
| TSPAN1 | tetraspanin 1 |
| TUBA3C | tubulin, alpha 3c |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WIZ | widely interspaced zinc finger motifs |
| WWOX | WW domain containing oxidoreductase |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF154 | zinc finger protein 154 |
| ZNF334 | zinc finger protein 334 |
| ZNF536 | zinc finger protein 536 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARRB2 | arrestin, beta 2 |
| ARSA | arylsulfatase A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATG10 | autophagy related 10 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AURKC | aurora kinase C |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC88C | coiled-coil domain containing 88C |
| CD53 | CD53 molecule |
| CDH7 | cadherin 7, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CISH | cytokine inducible SH2-containing protein |
| CLEC2B | C-type lectin domain family 2, member B |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRMP1 | collapsin response mediator protein 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DOK5 | docking protein 5 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM222B | family with sequence similarity 222, member B |
| FMO4 | flavin containing monooxygenase 4 |
| FMOD | fibromodulin |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GPR21 | G protein-coupled receptor 21 |
| GSTM5 | glutathione S-transferase mu 5 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4D | histone cluster 1, H4d |
| HOXC10 | homeobox C10 |
| HOXC11 | homeobox C11 |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KIRREL | kin of IRRE like (Drosophila) |
| LAMC3 | laminin, gamma 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MDM4 | MDM4, p53 regulator |
| MIS18BP1 | MIS18 binding protein 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MX1 | MX dynamin-like GTPase 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NKX3-2 | NK3 homeobox 2 |
| OSTF1 | osteoclast stimulating factor 1 |
| PAQR5 | progestin and adipoQ receptor family member V |
| PDE8B | phosphodiesterase 8B |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PENK | proenkephalin |
| PGPEP1 | pyroglutamyl-peptidase I |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRR14L | proline rich 14-like |
| PRSS53 | protease, serine, 53 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCG2 | secretogranin II |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| STRA6 | stimulated by retinoic acid 6 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TLN1 | talin 1 |
| TMEM159 | transmembrane protein 159 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TTN | titin |
| TUBA4B | tubulin, alpha 4b |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WT1-AS | WT1 antisense RNA |
| WWC2 | WW and C2 domain containing 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF480 | zinc finger protein 480 |
| ZNF862 | zinc finger protein 862 |
