piperine-1327 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the piperine-1327 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AEN apoptosis enhancing nuclease
AKAP1 A kinase (PRKA) anchor protein 1
ARHGAP4 Rho GTPase activating protein 4
ARRB1 arrestin, beta 1
B3GAT3 beta-1,3-glucuronyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C14ORF159 chromosome 14 open reading frame 159
CDCP1 CUB domain containing protein 1
CHD3 chromodomain helicase DNA binding protein 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO7 coronin 7
COX4I1 cytochrome c oxidase subunit IV isoform 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND1A DENN/MADD domain containing 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DVL1 dishevelled segment polarity protein 1
EGR1 early growth response 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EML3 echinoderm microtubule associated protein like 3
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM3A family with sequence similarity 3, member A
FCAR Fc fragment of IgA receptor
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FJX1 four jointed box 1 (Drosophila)
GAMT guanidinoacetate N-methyltransferase
GCAT glycine C-acetyltransferase
GDF11 growth differentiation factor 11
GEMIN4 gem (nuclear organelle) associated protein 4
GMPPB GDP-mannose pyrophosphorylase B
HDLBP high density lipoprotein binding protein
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOMER3 homer scaffolding protein 3
HPS1 Hermansky-Pudlak syndrome 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGL immunoglobulin lambda locus
IL24 interleukin 24
IPO4 importin 4
IRF8 interferon regulatory factor 8
JMJD4 jumonji domain containing 4
KIAA0485 uncharacterized LOC57235
KIAA0586 KIAA0586
KIAA0754 KIAA0754
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LTBP2 latent transforming growth factor beta binding protein 2
METTL8 methyltransferase like 8
MTUS1 microtubule associated tumor suppressor 1
MYRF myelin regulatory factor
NF2 neurofibromin 2 (merlin)
NMT1 N-myristoyltransferase 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTSR1 neurotensin receptor 1 (high affinity)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBX2 pre-B-cell leukemia homeobox 2
POM121L2 POM121 transmembrane nucleoporin-like 2
PRR7 proline rich 7 (synaptic)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBKS ribokinase
RPAP2 RNA polymerase II associated protein 2
RSRC1 arginine/serine-rich coiled-coil 1
SAPCD1 suppressor APC domain containing 1
SCAI suppressor of cancer cell invasion
SDCCAG3 serologically defined colon cancer antigen 3
SIPA1 signal-induced proliferation-associated 1
SIRAL2 SIR2 antiphage like 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMYD2 SET and MYND domain containing 2
SNRK SNF related kinase
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRSF7 serine/arginine-rich splicing factor 7
SUGP1 SURP and G patch domain containing 1
TBL2 transducin (beta)-like 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEP1 telomerase-associated protein 1
THBS4 thrombospondin 4
TMEM177 transmembrane protein 177
TMEM8A transmembrane protein 8A
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
U2SURP U2 snRNP-associated SURP domain containing
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBOX5 U-box domain containing 5
ZMYND8 zinc finger, MYND-type containing 8
ZNF692 zinc finger protein 692
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACPP acid phosphatase, prostate
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ATAD2 ATPase family, AAA domain containing 2
BBC3 BCL2 binding component 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C21ORF91 chromosome 21 open reading frame 91
CBX4 chromobox homolog 4
CDK3 cyclin-dependent kinase 3
CNR2 cannabinoid receptor 2 (macrophage)
COQ4 coenzyme Q4
CRIP1 cysteine-rich protein 1 (intestinal)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGAT1 diacylglycerol O-acyltransferase 1
EDC3 enhancer of mRNA decapping 3
ELP3 elongator acetyltransferase complex subunit 3
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FANCC Fanconi anemia, complementation group C
FASTKD5 FAST kinase domains 5
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR65 G protein-coupled receptor 65
GRWD1 glutamate-rich WD repeat containing 1
H2BFS H2B histone family, member S (pseudogene)
HCFC2 host cell factor C2
HYAL3 hyaluronoglucosaminidase 3
IFT81 intraflagellar transport 81
IMPAD1 inositol monophosphatase domain containing 1
INF2 inverted formin, FH2 and WH2 domain containing
KANSL1L KAT8 regulatory NSL complex subunit 1-like
LIMD2 LIM domain containing 2
LMAN1 lectin, mannose-binding, 1
LRRK1 leucine-rich repeat kinase 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBD5 methyl-CpG binding domain protein 5
MGC12488
MOGS mannosyl-oligosaccharide glucosidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYL5 myosin, light chain 5, regulatory
NUBP2 nucleotide binding protein 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PANK4 pantothenate kinase 4
PDLIM2 PDZ and LIM domain 2 (mystique)
PGPEP1 pyroglutamyl-peptidase I
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLS1 plastin 1
POLH polymerase (DNA directed), eta
POTEKP POTE ankyrin domain family, member K, pseudogene
RAB33B RAB33B, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNF25 ring finger protein 25
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPW1 selenoprotein W, 1
SETD1B SET domain containing 1B
SIDT1 SID1 transmembrane family, member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SPRYD7 SPRY domain containing 7
SYNJ2BP synaptojanin 2 binding protein
TBC1D17 TBC1 domain family, member 17
TBCCD1 TBCC domain containing 1
TBXAS1 thromboxane A synthase 1 (platelet)
TCTN2 tectonic family member 2
TET3 tet methylcytosine dioxygenase 3
THBS3 thrombospondin 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR4 toll-like receptor 4
TMEM184C transmembrane protein 184C
TMEM242 transmembrane protein 242
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNNT1 troponin T type 1 (skeletal, slow)
TRIM25 tripartite motif containing 25
TTC33 tetratricopeptide repeat domain 33
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
TWSG1 twisted gastrulation BMP signaling modulator 1
VANGL1 VANGL planar cell polarity protein 1
XAB2 XPA binding protein 2
YIPF1 Yip1 domain family, member 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF212 zinc finger protein 212
ZNF35 zinc finger protein 35
ZNF510 zinc finger protein 510
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816
ZNF862 zinc finger protein 862