piperine-3263 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the piperine-3263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADGRL1 adhesion G protein-coupled receptor L1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP26 Rho GTPase activating protein 26
ARL4C ADP-ribosylation factor-like 4C
C11ORF1 chromosome 11 open reading frame 1
C1ORF54 chromosome 1 open reading frame 54
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC88A coiled-coil domain containing 88A
CCNT2 cyclin T2
CDRT1 CMT1A duplicated region transcript 1
CEP250 centrosomal protein 250kDa
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEPDC5 DEP domain containing 5
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ESR1 estrogen receptor 1
FLT4 fms-related tyrosine kinase 4
FST follistatin
GJB3 gap junction protein, beta 3, 31kDa
GLS glutaminase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
GNAS GNAS complex locus
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HIST1H2AI histone cluster 1, H2ai
HOXD1 homeobox D1
ICOSLG inducible T-cell co-stimulator ligand
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IL17RC interleukin 17 receptor C
IL22 interleukin 22
IL5RA interleukin 5 receptor, alpha
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIAA0125 KIAA0125
KIAA0355 KIAA0355
KITLG KIT ligand
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LAMB2 laminin, beta 2 (laminin S)
LIN7B lin-7 homolog B (C. elegans)
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARS methionyl-tRNA synthetase
MEIS2 Meis homeobox 2
MFAP3L microfibrillar-associated protein 3-like
MORN1 MORN repeat containing 1
MTA1 metastasis associated 1
MTM1 myotubularin 1
MYL10 myosin, light chain 10, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NPY4R neuropeptide Y receptor Y4
NUMA1 nuclear mitotic apparatus protein 1
OBSL1 obscurin-like 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD6 programmed cell death 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
PMM1 phosphomannomutase 1
PRB4 proline-rich protein BstNI subfamily 4
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SETD1A SET domain containing 1A
SFTPD surfactant protein D
SGSM3 small G protein signaling modulator 3
SH2D1A SH2 domain containing 1A
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35E2 solute carrier family 35, member E2
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA6 stimulated by retinoic acid 6
SYNC syncoilin, intermediate filament protein
TAGLN3 transgelin 3
TFPI2 tissue factor pathway inhibitor 2
TP53I11 tumor protein p53 inducible protein 11
TRD T cell receptor delta locus
UBE3B ubiquitin protein ligase E3B
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VIPR1 vasoactive intestinal peptide receptor 1
WDR78 WD repeat domain 78
YPEL1 yippee-like 1 (Drosophila)
ZFP37 ZFP37 zinc finger protein
ZNF365 zinc finger protein 365
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ALS2CL ALS2 C-terminal like
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
C11ORF80 chromosome 11 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C5AR2 complement component 5a receptor 2
CBX8 chromobox homolog 8
CCNT1 cyclin T1
CSF1R colony stimulating factor 1 receptor
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DCAF16 DDB1 and CUL4 associated factor 16
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FAM155B family with sequence similarity 155, member B
FOSL1 FOS-like antigen 1
GBP2 guanylate binding protein 2, interferon-inducible
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H2BO histone cluster 1, H2bo
HIST1H4F histone cluster 1, H4f
IFT140 intraflagellar transport 140
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0754 KIAA0754
KLK5 kallikrein-related peptidase 5
KRI1 KRI1 homolog (S. cerevisiae)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRP5L low density lipoprotein receptor-related protein 5-like
MAP9 microtubule-associated protein 9
MBOAT2 membrane bound O-acyltransferase domain containing 2
MED18 mediator complex subunit 18
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NEK11 NIMA-related kinase 11
NOD1 nucleotide-binding oligomerization domain containing 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSMR oncostatin M receptor
OTUD3 OTU deubiquitinase 3
OVOL1 ovo-like zinc finger 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
PRICKLE3 prickle homolog 3 (Drosophila)
PTDSS2 phosphatidylserine synthase 2
QSER1 glutamine and serine rich 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS17P5 ribosomal protein S17 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCAMP4 secretory carrier membrane protein 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAI2 snail family zinc finger 2
SOX3 SRY (sex determining region Y)-box 3
SPAG7 sperm associated antigen 7
SPIDR scaffolding protein involved in DNA repair
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TICAM1 toll-like receptor adaptor molecule 1
TRIM5 tripartite motif containing 5
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED8 zinc finger, BED-type containing 8
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF254 zinc finger protein 254
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF85 zinc finger protein 85