| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the piperine-3263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARL4C | ADP-ribosylation factor-like 4C |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC88A | coiled-coil domain containing 88A |
| CCNT2 | cyclin T2 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP250 | centrosomal protein 250kDa |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DEPDC5 | DEP domain containing 5 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGR1 | early growth response 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ESR1 | estrogen receptor 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FST | follistatin |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLS | glutaminase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| GNAS | GNAS complex locus |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXD1 | homeobox D1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL11 | interleukin 11 |
| IL17RC | interleukin 17 receptor C |
| IL22 | interleukin 22 |
| IL5RA | interleukin 5 receptor, alpha |
| ING4 | inhibitor of growth family, member 4 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KIAA0125 | KIAA0125 |
| KIAA0355 | KIAA0355 |
| KITLG | KIT ligand |
| KLRAP1 | killer cell lectin-like receptor subfamily A pseudogene 1 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MARS | methionyl-tRNA synthetase |
| MEIS2 | Meis homeobox 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MORN1 | MORN repeat containing 1 |
| MTA1 | metastasis associated 1 |
| MTM1 | myotubularin 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NPY4R | neuropeptide Y receptor Y4 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OBSL1 | obscurin-like 1 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDCD6 | programmed cell death 6 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLK3 | polo-like kinase 3 |
| PMM1 | phosphomannomutase 1 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SETD1A | SET domain containing 1A |
| SFTPD | surfactant protein D |
| SGSM3 | small G protein signaling modulator 3 |
| SH2D1A | SH2 domain containing 1A |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35E2 | solute carrier family 35, member E2 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STRA6 | stimulated by retinoic acid 6 |
| SYNC | syncoilin, intermediate filament protein |
| TAGLN3 | transgelin 3 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRD | T cell receptor delta locus |
| UBE3B | ubiquitin protein ligase E3B |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR78 | WD repeat domain 78 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF365 | zinc finger protein 365 |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| ALS2CL | ALS2 C-terminal like |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B9D2 | B9 protein domain 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C5AR2 | complement component 5a receptor 2 |
| CBX8 | chromobox homolog 8 |
| CCNT1 | cyclin T1 |
| CSF1R | colony stimulating factor 1 receptor |
| CUEDC1 | CUE domain containing 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOC2A | double C2-like domains, alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP13 | dual specificity phosphatase 13 |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXO5 | exonuclease 5 |
| FAM131A | family with sequence similarity 131, member A |
| FAM155B | family with sequence similarity 155, member B |
| FOSL1 | FOS-like antigen 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4F | histone cluster 1, H4f |
| IFT140 | intraflagellar transport 140 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0754 | KIAA0754 |
| KLK5 | kallikrein-related peptidase 5 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAP9 | microtubule-associated protein 9 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MED18 | mediator complex subunit 18 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NEK11 | NIMA-related kinase 11 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OSMR | oncostatin M receptor |
| OTUD3 | OTU deubiquitinase 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLXNA3 | plexin A3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTDSS2 | phosphatidylserine synthase 2 |
| QSER1 | glutamine and serine rich 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF122 | ring finger protein 122 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAI2 | snail family zinc finger 2 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPAG7 | sperm associated antigen 7 |
| SPIDR | scaffolding protein involved in DNA repair |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TRIM5 | tripartite motif containing 5 |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASH1 | vasohibin 1 |
| VEGFB | vascular endothelial growth factor B |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF205 | zinc finger protein 205 |
| ZNF254 | zinc finger protein 254 |
| ZNF623 | zinc finger protein 623 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| ZNF85 | zinc finger protein 85 |