piperine-4247 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the piperine-4247 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1D1 aldo-keto reductase family 1, member D1
ALDOB aldolase B, fructose-bisphosphate
ARHGAP28 Rho GTPase activating protein 28
ASIP agouti signaling protein
ASPN asporin
ASTN2 astrotactin 2
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN7L1 ataxin 7-like 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2 B-cell CLL/lymphoma 2
BTN3A1 butyrophilin, subfamily 3, member A1
CCDC177 coiled-coil domain containing 177
CCDC28B coiled-coil domain containing 28B
CCDC7 coiled-coil domain containing 7
CIB2 calcium and integrin binding family member 2
CLDN8 claudin 8
CLSTN3 calsyntenin 3
CLTCL1 clathrin, heavy chain-like 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DKFZP434C153 DKFZP434C153 protein
DMBT1 deleted in malignant brain tumors 1
EDA ectodysplasin A
EDN3 endothelin 3
ELL2 elongation factor, RNA polymerase II, 2
EML2 echinoderm microtubule associated protein like 2
ERC2 ELKS/RAB6-interacting/CAST family member 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESRRG estrogen-related receptor gamma
FBXO31 F-box protein 31
FGL2 fibrinogen-like 2
GLB1L galactosidase, beta 1-like
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPATCH4 G patch domain containing 4
HBS1L HBS1-like translational GTPase
HIST1H4B histone cluster 1, H4b
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPG2 heparan sulfate proteoglycan 2
IFT27 intraflagellar transport 27
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1109 KIAA1109
KRT7 keratin 7, type II
LAMA2 laminin, alpha 2
LCMT2 leucine carboxyl methyltransferase 2
LDHC lactate dehydrogenase C
LOX lysyl oxidase
MAP2 microtubule-associated protein 2
MED16 mediator complex subunit 16
MEFV Mediterranean fever
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MTRF1L mitochondrial translational release factor 1-like
MUC13 mucin 13, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NME5 NME/NM23 family member 5
NPY5R neuropeptide Y receptor Y5
NRIP3 nuclear receptor interacting protein 3
PCDH17 protocadherin 17
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PGP phosphoglycolate phosphatase
PHC3 polyhomeotic homolog 3 (Drosophila)
PKP4 plakophilin 4
POU5F1B POU class 5 homeobox 1B
PTN pleiotrophin
PTPRR protein tyrosine phosphatase, receptor type, R
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIMS3 regulating synaptic membrane exocytosis 3
RPS14 ribosomal protein S14
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SH3BP2 SH3-domain binding protein 2
SLAMF7 SLAM family member 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD5-AS1 SMAD5 antisense RNA 1
SPON1 spondin 1, extracellular matrix protein
SUGP1 SURP and G patch domain containing 1
SUSD5 sushi domain containing 5
SYT17 synaptotagmin XVII
TAT tyrosine aminotransferase
TBC1D30 TBC1 domain family, member 30
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM29 tripartite motif containing 29
TSC22D2 TSC22 domain family, member 2
UBE2I ubiquitin-conjugating enzyme E2I
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP64 ZFP64 zinc finger protein
ZNF219 zinc finger protein 219
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADGRB2 adhesion G protein-coupled receptor B2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12 arachidonate 12-lipoxygenase
ANXA2P1 annexin A2 pseudogene 1
AXIN1 axin 1
C1RL complement component 1, r subcomponent-like
C22ORF46 chromosome 22 open reading frame 46
CCNO cyclin O
CD68 CD68 molecule
CDT1 chromatin licensing and DNA replication factor 1
CFAP45 cilia and flagella associated protein 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCA1 chloride channel accessory 1
CLDN1 claudin 1
CLDN11 claudin 11
CNOT3 CCR4-NOT transcription complex, subunit 3
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF21 chromosome X open reading frame 21
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DOK5 docking protein 5
ERO1LB ERO1-like beta (S. cerevisiae)
EYA3 EYA transcriptional coactivator and phosphatase 3
FADS2 fatty acid desaturase 2
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FKBP5 FK506 binding protein 5
FOXD1 forkhead box D1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HIST1H3B histone cluster 1, H3b
HPR haptoglobin-related protein
IL2 interleukin 2
IL36RN interleukin 36 receptor antagonist
KANSL3 KAT8 regulatory NSL complex subunit 3
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPAR4 lysophosphatidic acid receptor 4
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFGE8 milk fat globule-EGF factor 8 protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MTSS1L metastasis suppressor 1-like
MYL9 myosin, light chain 9, regulatory
MYO15A myosin XVA
NOTCH4 notch 4
NRGN neurogranin (protein kinase C substrate, RC3)
OLFML3 olfactomedin-like 3
OSBP2 oxysterol binding protein 2
PARM1 prostate androgen-regulated mucin-like protein 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLAG1 pleiomorphic adenoma gene 1
PLBD1 phospholipase B domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLL polymerase (DNA directed), lambda
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRF1 perforin 1 (pore forming protein)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRM2 protamine 2
PRSS53 protease, serine, 53
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
ROGDI rogdi homolog (Drosophila)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A3 S100 calcium binding protein A3
SDAD1 SDA1 domain containing 1
SECTM1 secreted and transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SGK2 serum/glucocorticoid regulated kinase 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMR3A submaxillary gland androgen regulated protein 3A
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
STIM1 stromal interaction molecule 1
TBC1D22B TBC1 domain family, member 22B
TLN1 talin 1
TMEM183A transmembrane protein 183A
TMEM184C transmembrane protein 184C
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT1 wingless-type MMTV integration site family, member 1
ZNF222 zinc finger protein 222
ZNF324 zinc finger protein 324
ZNF76 zinc finger protein 76
ZYX zyxin