piperine-4830 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the piperine-4830 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
APC adenomatous polyposis coli
AQP9 aquaporin 9
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATXN2L ataxin 2-like
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C18ORF25 chromosome 18 open reading frame 25
C1ORF61 chromosome 1 open reading frame 61
C22ORF46 chromosome 22 open reading frame 46
CDK13 cyclin-dependent kinase 13
CFHR2 complement factor H-related 2
CLCA2 chloride channel accessory 2
CLCN7 chloride channel, voltage-sensitive 7
CLIC5 chloride intracellular channel 5
COL1A1 collagen, type I, alpha 1
COL6A2 collagen, type VI, alpha 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCSTAMP dendrocyte expressed seven transmembrane protein
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DMC1 DNA meiotic recombinase 1
DMXL2 Dmx-like 2
DOPEY2 dopey family member 2
DPF3 D4, zinc and double PHD fingers, family 3
EN2 engrailed homeobox 2
FAM13C family with sequence similarity 13, member C
FAM149B1 family with sequence similarity 149, member B1
FGL1 fibrinogen-like 1
FSCN3 fascin actin-bundling protein 3, testicular
FUT2 fucosyltransferase 2 (secretor status included)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
GSK3A glycogen synthase kinase 3 alpha
HBS1L HBS1-like translational GTPase
HIST1H1E histone cluster 1, H1e
HOXA4 homeobox A4
HOXC8 homeobox C8
IL1B interleukin 1, beta
ITGB7 integrin, beta 7
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL1 kelch-like family member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT38 keratin 38, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LIF leukemia inhibitory factor
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC399491
LOX lysyl oxidase
MEF2D myocyte enhancer factor 2D
MST1 macrophage stimulating 1
NCR2 natural cytotoxicity triggering receptor 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDCD3 NudC domain containing 3
OGFR opioid growth factor receptor
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAX9 paired box 9
PCDHGA10 protocadherin gamma subfamily A, 10
PCLO piccolo presynaptic cytomatrix protein
PDE9A phosphodiesterase 9A
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS3 protease, serine, 3
RAB6A RAB6A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RGS12 regulator of G-protein signaling 12
RGS9 regulator of G-protein signaling 9
RNF122 ring finger protein 122
RPL7 ribosomal protein L7
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPD surfactant protein D
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOS2 son of sevenless homolog 2 (Drosophila)
SRSF7 serine/arginine-rich splicing factor 7
STS steroid sulfatase (microsomal), isozyme S
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN3 synapsin III
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF3 transcription factor 3
TGFA transforming growth factor, alpha
TGFBR1 transforming growth factor, beta receptor 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UBXN1 UBX domain protein 1
USP48 ubiquitin specific peptidase 48
UTRN utrophin
WSCD1 WSC domain containing 1
ZNF440 zinc finger protein 440
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ASTE1 asteroid homolog 1 (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BTF3P12 basic transcription factor 3 pseudogene 12
C2ORF44 chromosome 2 open reading frame 44
CASD1 CAS1 domain containing 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CENPJ centromere protein J
CENPT centromere protein T
CEP97 centrosomal protein 97kDa
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CIR1 corepressor interacting with RBPJ, 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CORO7 coronin 7
CRABP1 cellular retinoic acid binding protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ELOVL4 ELOVL fatty acid elongase 4
ELP3 elongator acetyltransferase complex subunit 3
EMD emerin
FAM169A family with sequence similarity 169, member A
FAM184A family with sequence similarity 184, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXO3 F-box protein 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUZ fuzzy planar cell polarity protein
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
HIST1H2BF histone cluster 1, H2bf
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INPPL1 inositol polyphosphate phosphatase-like 1
IREB2 iron-responsive element binding protein 2
JUNB jun B proto-oncogene
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRT8P12 keratin 8 pseudogene 12
LNPEP leucyl/cystinyl aminopeptidase
LRRC16A leucine rich repeat containing 16A
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MPDU1 mannose-P-dolichol utilization defect 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXD3 MAX dimerization protein 3
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NKAIN1 Na+/K+ transporting ATPase interacting 1
NNT nicotinamide nucleotide transhydrogenase
NPY5R neuropeptide Y receptor Y5
NT5DC3 5'-nucleotidase domain containing 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OCRL oculocerebrorenal syndrome of Lowe
OTUD3 OTU deubiquitinase 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB3 protocadherin beta 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PISD phosphatidylserine decarboxylase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRSS16 protease, serine, 16 (thymus)
PTCD2 pentatricopeptide repeat domain 2
PTDSS2 phosphatidylserine synthase 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RIC8B RIC8 guanine nucleotide exchange factor B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
SCAF4 SR-related CTD-associated factor 4
SDAD1 SDA1 domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2D4A SH2 domain containing 4A
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIDT1 SID1 transmembrane family, member 1
SIX1 SIX homeobox 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMIM8 small integral membrane protein 8
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TCTA T-cell leukemia translocation altered
TLN1 talin 1
TMEM230 transmembrane protein 230
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBXN6 UBX domain protein 6
USP18 ubiquitin specific peptidase 18
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR25 WD repeat domain 25
YEATS4 YEATS domain containing 4
ZNF253 zinc finger protein 253
ZNF430 zinc finger protein 430
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862