piracetam-5462 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the piracetam-5462 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AK2 adenylate kinase 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX12 arachidonate 12-lipoxygenase
ANGPTL4 angiopoietin-like 4
ANP32A-IT1 ANP32A intronic transcript 1
ARG1 arginase 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAIAP2 BAI1-associated protein 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTN3A1 butyrophilin, subfamily 3, member A1
C2CD2L C2CD2-like
C3ORF18 chromosome 3 open reading frame 18
CA5B carbonic anhydrase VB, mitochondrial
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCNT2 cyclin T2
CDC25C cell division cycle 25C
CDRT1 CMT1A duplicated region transcript 1
CHN2 chimerin 2
CSF1R colony stimulating factor 1 receptor
CTBP2 C-terminal binding protein 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNASE1L3 deoxyribonuclease I-like 3
DOK2 docking protein 2, 56kDa
DOPEY2 dopey family member 2
ELSPBP1 epididymal sperm binding protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERP44 endoplasmic reticulum protein 44
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FH fumarate hydratase
FLJ42627 uncharacterized LOC645644
FXYD5 FXYD domain containing ion transport regulator 5
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL galanin/GMAP prepropeptide
GLIPR1 GLI pathogenesis-related 1
GPATCH3 G patch domain containing 3
GPR21 G protein-coupled receptor 21
GPR87 G protein-coupled receptor 87
HOXA4 homeobox A4
HOXA9 homeobox A9
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ING2 inhibitor of growth family, member 2
ITPK1 inositol-tetrakisphosphate 1-kinase
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA0930 KIAA0930
KLF6 Kruppel-like factor 6
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMC2 laminin, gamma 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LRP4 low density lipoprotein receptor-related protein 4
MZF1 myeloid zinc finger 1
NPHP1 nephronophthisis 1 (juvenile)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCG1 phospholipase C, gamma 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAD51 RAD51 recombinase
RANGAP1 Ran GTPase activating protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
RCAN3 RCAN family member 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RORC RAR-related orphan receptor C
RREB1 ras responsive element binding protein 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A4 S100 calcium binding protein A4
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX13 sorting nexin 13
SYMPK symplekin
TFF2 trefoil factor 2
TM4SF5 transmembrane 4 L six family member 5
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSC22D3 TSC22 domain family, member 3
TSC22D4 TSC22 domain family, member 4
TUBGCP3 tubulin, gamma complex associated protein 3
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
ZNF227 zinc finger protein 227
ZNF532 zinc finger protein 532
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMDHD2 amidohydrolase domain containing 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARSB arylsulfatase B
ASPHD1 aspartate beta-hydroxylase domain containing 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHPF chondroitin polymerizing factor
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPTP ceramide-1-phosphate transfer protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ELP3 elongator acetyltransferase complex subunit 3
FAM169A family with sequence similarity 169, member A
FAM86C1 family with sequence similarity 86, member C1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBPL FK506 binding protein like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSD1 fibronectin type III and SPRY domain containing 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPX2 glutathione peroxidase 2
HIST1H2AE histone cluster 1, H2ae
HS1BP3 HCLS1 binding protein 3
IL15RA interleukin 15 receptor, alpha
IL2 interleukin 2
KAT2A K(lysine) acetyltransferase 2A
KLHL36 kelch-like family member 36
LAMA3 laminin, alpha 3
LHFPL2 lipoma HMGIC fusion partner-like 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
LZTFL1 leucine zipper transcription factor-like 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MPI mannose phosphate isomerase
MUC3A mucin 3A, cell surface associated
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5C 5', 3'-nucleotidase, cytosolic
OGFRL1 opioid growth factor receptor-like 1
ONECUT2 one cut homeobox 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PITX2 paired-like homeodomain 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPT2 palmitoyl-protein thioesterase 2
PROCR protein C receptor, endothelial
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAS related RAS viral (r-ras) oncogene homolog
SCN1B sodium channel, voltage gated, type I beta subunit
SDF2 stromal cell-derived factor 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SETMAR SET domain and mariner transposase fusion gene
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMYD5 SMYD family member 5
SNIP1 Smad nuclear interacting protein 1
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TESC tescalcin
TEX264 testis expressed 264
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC7 transmembrane channel-like 7
TMEM115 transmembrane protein 115
TOLLIP toll interacting protein
TPST1 tyrosylprotein sulfotransferase 1
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
WDR18 WD repeat domain 18
ZNF574 zinc finger protein 574
ZNF639 zinc finger protein 639
ZSCAN9 zinc finger and SCAN domain containing 9