| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the pirenperone-2455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACTN2 | actinin, alpha 2 |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APAF1 | apoptotic peptidase activating factor 1 |
| B9D1 | B9 protein domain 1 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BMP7 | bone morphogenetic protein 7 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC85B | coiled-coil domain containing 85B |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHM | choroideremia (Rab escort protein 1) |
| CLEC3B | C-type lectin domain family 3, member B |
| CPE | carboxypeptidase E |
| CTBP2 | C-terminal binding protein 2 |
| CTRL | chymotrypsin-like |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FBXO31 | F-box protein 31 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| FOSL2 | FOS-like antigen 2 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GIGYF2 | GRB10 interacting GYF protein 2 |
| GK | glycerol kinase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPM6B | glycoprotein M6B |
| GPR132 | G protein-coupled receptor 132 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HN1L | hematological and neurological expressed 1-like |
| HRH4 | histamine receptor H4 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IGHM | immunoglobulin heavy constant mu |
| INCENP | inner centromere protein antigens 135/155kDa |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KHSRP | KH-type splicing regulatory protein |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| KRT24 | keratin 24, type I |
| LPIN1 | lipin 1 |
| LTB4R | leukotriene B4 receptor |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAOA | monoamine oxidase A |
| MCAM | melanoma cell adhesion molecule |
| MCL1 | myeloid cell leukemia 1 |
| MFAP3 | microfibrillar-associated protein 3 |
| MKRN3 | makorin ring finger protein 3 |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NCLN | nicalin |
| NEK9 | NIMA-related kinase 9 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PICK1 | protein interacting with PRKCA 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLCE1 | phospholipase C, epsilon 1 |
| PLK4 | polo-like kinase 4 |
| PMEL | premelanosome protein |
| PTK2B | protein tyrosine kinase 2 beta |
| RAB13 | RAB13, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGRIP1L | RPGRIP1-like |
| RPL10L | ribosomal protein L10-like |
| RUNX1 | runt-related transcription factor 1 |
| S100A11 | S100 calcium binding protein A11 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SMAD3 | SMAD family member 3 |
| SMTN | smoothelin |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SP1 | Sp1 transcription factor |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SQSTM1 | sequestosome 1 |
| STAT5B | signal transducer and activator of transcription 5B |
| STK3 | serine/threonine kinase 3 |
| SV2C | synaptic vesicle glycoprotein 2C |
| SYCP2 | synaptonemal complex protein 2 |
| SYK | spleen tyrosine kinase |
| TEX40 | testis expressed 40 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TLR6 | toll-like receptor 6 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRD | T cell receptor delta locus |
| TRIM23 | tripartite motif containing 23 |
| TRIM25 | tripartite motif containing 25 |
| TRIM62 | tripartite motif containing 62 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF24 | zinc finger protein 24 |
| Symbol | Name |
|---|---|
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BPI | bactericidal/permeability-increasing protein |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNM3 | dynamin 3 |
| DOCK4 | dedicator of cytokinesis 4 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA4 | EPH receptor A4 |
| EPHB6 | EPH receptor B6 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOSC1 | exosome component 1 |
| FAM102A | family with sequence similarity 102, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| G6PD | glucose-6-phosphate dehydrogenase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR65 | G protein-coupled receptor 65 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAMP | hepcidin antimicrobial peptide |
| HDAC7 | histone deacetylase 7 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AI | histone cluster 1, H2ai |
| HOPX | HOP homeobox |
| HS1BP3 | HCLS1 binding protein 3 |
| IL2 | interleukin 2 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| KLHL26 | kelch-like family member 26 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC257152 | uncharacterized LOC257152 |
| LRRC42 | leucine rich repeat containing 42 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK10 | mitogen-activated protein kinase 10 |
| MEFV | Mediterranean fever |
| MEGF8 | multiple EGF-like-domains 8 |
| MYH15 | myosin, heavy chain 15 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCBP4 | poly(rC) binding protein 4 |
| PDGFD | platelet derived growth factor D |
| PER3 | period circadian clock 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| SCG5 | secretogranin V |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI1 | snail family zinc finger 1 |
| SPATA1 | spermatogenesis associated 1 |
| SPRR2B | small proline-rich protein 2B |
| STAT5A | signal transducer and activator of transcription 5A |
| STX11 | syntaxin 11 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM254 | transmembrane protein 254 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA4B | tubulin, alpha 4b |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VEGFC | vascular endothelial growth factor C |
| VNN1 | vanin 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR33 | WD repeat domain 33 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZNF219 | zinc finger protein 219 |
| ZNF276 | zinc finger protein 276 |
| ZNF324 | zinc finger protein 324 |
