| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pirenperone-3316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BNC2 | basonuclin 2 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCA1 | chloride channel accessory 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRTAC1 | cartilage acidic protein 1 |
| CRYGD | crystallin, gamma D |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DEPDC5 | DEP domain containing 5 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DICER1 | dicer 1, ribonuclease type III |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DRD2 | dopamine receptor D2 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ETV7 | ets variant 7 |
| FAM212B | family with sequence similarity 212, member B |
| FOSL2 | FOS-like antigen 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GK | glycerol kinase |
| GLB1L | galactosidase, beta 1-like |
| GLRA3 | glycine receptor, alpha 3 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GRAMD1C | GRAM domain containing 1C |
| GSTA3 | glutathione S-transferase alpha 3 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HFE | hemochromatosis |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| INO80D | INO80 complex subunit D |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KLHL24 | kelch-like family member 24 |
| KRT17 | keratin 17, type I |
| KRT19P2 | keratin 19 pseudogene 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LY86 | lymphocyte antigen 86 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| MYO1B | myosin IB |
| NDRG2 | NDRG family member 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NKX3-2 | NK3 homeobox 2 |
| NUP214 | nucleoporin 214kDa |
| ONECUT2 | one cut homeobox 2 |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDCD1 | programmed cell death 1 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP | prolactin-induced protein |
| PLIN2 | perilipin 2 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PXDC1 | PX domain containing 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHO | rhodopsin |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SOD3 | superoxide dismutase 3, extracellular |
| SRPK2 | SRSF protein kinase 2 |
| STOML1 | stomatin (EPB72)-like 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYT5 | synaptotagmin V |
| TAPBP | TAP binding protein (tapasin) |
| TDRD12 | tudor domain containing 12 |
| TEF | thyrotrophic embryonic factor |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TOR4A | torsin family 4, member A |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TRGV5 | T cell receptor gamma variable 5 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| VPRBP | Vpr (HIV-1) binding protein |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF589 | zinc finger protein 589 |
| ZNF646 | zinc finger protein 646 |
| ZNF76 | zinc finger protein 76 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFAP1 | actin filament associated protein 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARMC4 | armadillo repeat containing 4 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AXIN1 | axin 1 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C3 | complement component 3 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALML5 | calmodulin-like 5 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBX8 | chromobox homolog 8 |
| CCDC68 | coiled-coil domain containing 68 |
| CISH | cytokine inducible SH2-containing protein |
| CLGN | calmegin |
| CLK1 | CDC-like kinase 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CORO7 | coronin 7 |
| CTRL | chymotrypsin-like |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EPHA2 | EPH receptor A2 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FBXO46 | F-box protein 46 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXC1 | forkhead box C1 |
| FOXO1 | forkhead box O1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GAB2 | GRB2-associated binding protein 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPATCH2L | G patch domain containing 2-like |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HDAC11 | histone deacetylase 11 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H2AM | histone cluster 1, H2am |
| IFI35 | interferon-induced protein 35 |
| IQCG | IQ motif containing G |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIF20A | kinesin family member 20A |
| KLHL12 | kelch-like family member 12 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINS | lines homolog (Drosophila) |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MSI1 | musashi RNA-binding protein 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PITX2 | paired-like homeodomain 2 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPAN | peter pan homolog (Drosophila) |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOC | ras homolog family member C |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF170 | ring finger protein 170 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL10L | ribosomal protein L10-like |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| SETD1B | SET domain containing 1B |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STRN | striatin, calmodulin binding protein |
| STX1A | syntaxin 1A (brain) |
| TMEM53 | transmembrane protein 53 |
| TMEM62 | transmembrane protein 62 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| WDR62 | WD repeat domain 62 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF124 | zinc finger protein 124 |
| ZNF365 | zinc finger protein 365 |
| ZNF696 | zinc finger protein 696 |
| ZNF701 | zinc finger protein 701 |
