| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pirenperone-5274 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BGN | biglycan |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNJL | cyclin J-like |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CD300A | CD300a molecule |
| CD52 | CD52 molecule |
| CD93 | CD93 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CTSF | cathepsin F |
| CYTH4 | cytohesin 4 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK4 | docking protein 4 |
| DTNB | dystrobrevin, beta |
| DUSP9 | dual specificity phosphatase 9 |
| DVL2 | dishevelled segment polarity protein 2 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELAC2 | elaC ribonuclease Z 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| EPHB2 | EPH receptor B2 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF22 | fibroblast growth factor 22 |
| FOXG1 | forkhead box G1 |
| FPR1 | formyl peptide receptor 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GM2A | GM2 ganglioside activator |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| HDAC5 | histone deacetylase 5 |
| HSF4 | heat shock transcription factor 4 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| IRF4 | interferon regulatory factor 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KALRN | kalirin, RhoGEF kinase |
| KRT31 | keratin 31, type I |
| KSR1 | kinase suppressor of ras 1 |
| LAG3 | lymphocyte-activation gene 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MCAM | melanoma cell adhesion molecule |
| MED16 | mediator complex subunit 16 |
| MEF2D | myocyte enhancer factor 2D |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP11 | matrix metallopeptidase 11 |
| MST1 | macrophage stimulating 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NELL2 | NEL-like 2 (chicken) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| PHF1 | PHD finger protein 1 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PICK1 | protein interacting with PRKCA 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLSCR3 | phospholipid scramblase 3 |
| PML | promyelocytic leukemia |
| PRKCB | protein kinase C, beta |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| R3HDM1 | R3H domain containing 1 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RND2 | Rho family GTPase 2 |
| SDC3 | syndecan 3 |
| SETBP1 | SET binding protein 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SNCAIP | synuclein, alpha interacting protein |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| TGFB2 | transforming growth factor, beta 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRIM10 | tripartite motif containing 10 |
| TSPAN2 | tetraspanin 2 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC13A | unc-13 homolog A (C. elegans) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ARMC4 | armadillo repeat containing 4 |
| ARRB1 | arrestin, beta 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CFD | complement factor D (adipsin) |
| CPA4 | carboxypeptidase A4 |
| CRLF1 | cytokine receptor-like factor 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEPDC5 | DEP domain containing 5 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DRD1 | dopamine receptor D1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETNK2 | ethanolamine kinase 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXO4 | F-box protein 4 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FUZ | fuzzy planar cell polarity protein |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPC3 | glypican 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD1C | GRAM domain containing 1C |
| GSTA4 | glutathione S-transferase alpha 4 |
| HAMP | hepcidin antimicrobial peptide |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC8 | homeobox C8 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| ITGA8 | integrin, alpha 8 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0319L | KIAA0319-like |
| KIF5A | kinesin family member 5A |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHX6 | LIM homeobox 6 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LY86 | lymphocyte antigen 86 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAK | male germ cell-associated kinase |
| MAL | mal, T-cell differentiation protein |
| MAPK10 | mitogen-activated protein kinase 10 |
| METTL16 | methyltransferase like 16 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP3 | matrix metallopeptidase 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRX1 | NLR family member X1 |
| NOL10 | nucleolar protein 10 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE12 | phosphodiesterase 12 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRR14L | proline rich 14-like |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RGS20 | regulator of G-protein signaling 20 |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TFF2 | trefoil factor 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UPP1 | uridine phosphorylase 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR62 | WD repeat domain 62 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZIC3 | Zic family member 3 |
| ZNF250 | zinc finger protein 250 |
| ZNF484 | zinc finger protein 484 |
| ZNF701 | zinc finger protein 701 |
| ZNF750 | zinc finger protein 750 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
