| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the pirenperone-5639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADD2 | adducin 2 (beta) |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG10 | autophagy related 10 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BARX2 | BARX homeobox 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP10 | bone morphogenetic protein 10 |
| BMP3 | bone morphogenetic protein 3 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CAMKV | CaM kinase-like vesicle-associated |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD22 | CD22 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDKL5 | cyclin-dependent kinase-like 5 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLSTN2 | calsyntenin 2 |
| CLTA | clathrin, light chain A |
| COL4A6 | collagen, type IV, alpha 6 |
| CSN2 | casein beta |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCTN1 | dynactin 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DUSP7 | dual specificity phosphatase 7 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF18 | fibroblast growth factor 18 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GAST | gastrin |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GOLGA8A | golgin A8 family, member A |
| GRM1 | glutamate receptor, metabotropic 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIC2 | hypermethylated in cancer 2 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IDUA | iduronidase, alpha-L- |
| KALRN | kalirin, RhoGEF kinase |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIF21B | kinesin family member 21B |
| KIF5A | kinesin family member 5A |
| LIMCH1 | LIM and calponin homology domains 1 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NEK9 | NIMA-related kinase 9 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPHP4 | nephronophthisis 4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POLL | polymerase (DNA directed), lambda |
| PON3 | paraoxonase 3 |
| PORCN | porcupine homolog (Drosophila) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RHEB | Ras homolog enriched in brain |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10 | ribosomal protein L10 |
| RPL7 | ribosomal protein L7 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SFTPC | surfactant protein C |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SHOX2 | short stature homeobox 2 |
| SKI | SKI proto-oncogene |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAOK2 | TAO kinase 2 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TSSK2 | testis-specific serine kinase 2 |
| UPK1A | uroplakin 1A |
| WDR62 | WD repeat domain 62 |
| WSCD1 | WSC domain containing 1 |
| XAF1 | XIAP associated factor 1 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ARMC4 | armadillo repeat containing 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP15 | bone morphogenetic protein 15 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC134 | coiled-coil domain containing 134 |
| CES3 | carboxylesterase 3 |
| CLGN | calmegin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRLF1 | cytokine receptor-like factor 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND5B | DENN/MADD domain containing 5B |
| DOCK4 | dedicator of cytokinesis 4 |
| DOK5 | docking protein 5 |
| EFNA3 | ephrin-A3 |
| EPN1 | epsin 1 |
| ETNK2 | ethanolamine kinase 2 |
| F9 | coagulation factor IX |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR1 | G protein-coupled receptor 1 |
| GPR27 | G protein-coupled receptor 27 |
| GPR3 | G protein-coupled receptor 3 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC11 | histone deacetylase 11 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4D | histone cluster 1, H4d |
| HOXA4 | homeobox A4 |
| HOXB2 | homeobox B2 |
| IFT140 | intraflagellar transport 140 |
| IL2RB | interleukin 2 receptor, beta |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KRT15 | keratin 15, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MMP2 | matrix metallopeptidase 2 |
| MVP | major vault protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEUROD4 | neuronal differentiation 4 |
| NLRX1 | NLR family member X1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| OSMR | oncostatin M receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA9 | protocadherin alpha 9 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G10 | phospholipase A2, group X |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RRAGB | Ras-related GTP binding B |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIRT2 | sirtuin 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SPAG4 | sperm associated antigen 4 |
| STRN | striatin, calmodulin binding protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TFF2 | trefoil factor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| XDH | xanthine dehydrogenase |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZFP37 | ZFP37 zinc finger protein |
| ZIC3 | Zic family member 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZW10 | zw10 kinetochore protein |