pirenzepine-1388 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pirenzepine-1388 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACP6 acid phosphatase 6, lysophosphatidic
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ANGEL1 angel homolog 1 (Drosophila)
ANKRD12 ankyrin repeat domain 12
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ATG13 autophagy related 13
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CBX4 chromobox homolog 4
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD300A CD300a molecule
CD8B CD8b molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CUL4B cullin 4B
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYB561 cytochrome b561
DBT dihydrolipoamide branched chain transacylase E2
DLK2 delta-like 2 homolog (Drosophila)
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DST dystonin
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
FAM102A family with sequence similarity 102, member A
FAM178A family with sequence similarity 178, member A
FAM64A family with sequence similarity 64, member A
FAS Fas cell surface death receptor
FBXO21 F-box protein 21
FPR2 formyl peptide receptor 2
G0S2 G0/G1 switch 2
GAP43 growth associated protein 43
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPC1 glypican 1
GRB7 growth factor receptor-bound protein 7
GUCA1A guanylate cyclase activator 1A (retina)
GUSBP3 glucuronidase, beta pseudogene 3
HOXD1 homeobox D1
IGSF9B immunoglobulin superfamily, member 9B
KRI1 KRI1 homolog (S. cerevisiae)
LGALS8 lectin, galactoside-binding, soluble, 8
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LPAR1 lysophosphatidic acid receptor 1
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
METTL5 methyltransferase like 5
MFN1 mitofusin 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTMR3 myotubularin related protein 3
MYO7A myosin VIIA
NOAZFP nucleolar atypical zinc finger
NOP16 NOP16 nucleolar protein
NXF2 nuclear RNA export factor 2
OCRL oculocerebrorenal syndrome of Lowe
OSGIN1 oxidative stress induced growth inhibitor 1
PADI2 peptidyl arginine deiminase, type II
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDGFB platelet-derived growth factor beta polypeptide
PIAS4 protein inhibitor of activated STAT, 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POMT2 protein-O-mannosyltransferase 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRR4 proline rich 4 (lacrimal)
PRRC2C proline-rich coiled-coil 2C
PTBP3 polypyrimidine tract binding protein 3
PTX3 pentraxin 3, long
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM25 RNA binding motif protein 25
RHOD ras homolog family member D
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF141 ring finger protein 141
RPAIN RPA interacting protein
RRP1 ribosomal RNA processing 1
SAMM50 SAMM50 sorting and assembly machinery component
SAP30 Sin3A-associated protein, 30kDa
SCYL3 SCY1-like 3 (S. cerevisiae)
SIGLEC6 sialic acid binding Ig-like lectin 6
SIRT3 sirtuin 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
STK19 serine/threonine kinase 19
STXBP1 syntaxin binding protein 1
SYNGR1 synaptogyrin 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TDRD3 tudor domain containing 3
TEAD4 TEA domain family member 4
TRD T cell receptor delta locus
TYR tyrosinase
VAMP5 vesicle-associated membrane protein 5
WDR13 WD repeat domain 13
WSB1 WD repeat and SOCS box containing 1
YLPM1 YLP motif containing 1
ZNF778 zinc finger protein 778
ZNF783 zinc finger family member 783
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
APOC4 apolipoprotein C-IV
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BST1 bone marrow stromal cell antigen 1
C19ORF24 chromosome 19 open reading frame 24
CCDC91 coiled-coil domain containing 91
CD151 CD151 molecule (Raph blood group)
CD302 CD302 molecule
CES1 carboxylesterase 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN11 claudin 11
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPA2 carboxypeptidase A2 (pancreatic)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYBG3 beta-gamma crystallin domain containing 3
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSL cathepsin L
DAZAP1 DAZ associated protein 1
DESI1 desumoylating isopeptidase 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYSF dysferlin
ECM1 extracellular matrix protein 1
ERCC6 excision repair cross-complementation group 6
ERF Ets2 repressor factor
FAF1 Fas (TNFRSF6) associated factor 1
FAM172A family with sequence similarity 172, member A
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
HAGH hydroxyacylglutathione hydrolase
HMGB3P1 high mobility group box 3 pseudogene 1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IFITM3 interferon induced transmembrane protein 3
IL2RB interleukin 2 receptor, beta
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD15 potassium channel tetramerization domain containing 15
KIAA0556 KIAA0556
KLHDC2 kelch domain containing 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIN37 lin-37 DREAM MuvB core complex component
LMTK1 lemur tail kinase 1
MAPK12 mitogen-activated protein kinase 12
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MTERF4 mitochondrial transcription termination factor 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NOD1 nucleotide-binding oligomerization domain containing 1
NRBP1 nuclear receptor binding protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUBP2 nucleotide binding protein 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
NXPH3 neurexophilin 3
OGFRL1 opioid growth factor receptor-like 1
ORAI3 ORAI calcium release-activated calcium modulator 3
OVGP1 oviductal glycoprotein 1, 120kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMM2 phosphomannomutase 2
PNOC prepronociceptin
PPIEL peptidylprolyl isomerase E-like pseudogene
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB4B RAB4B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RBM6 RNA binding motif protein 6
SERTAD3 SERTA domain containing 3
SH3GL1 SH3-domain GRB2-like 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SRRD SRR1 domain containing
STARD8 StAR-related lipid transfer (START) domain containing 8
STK39 serine threonine kinase 39
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL3 transducin (beta)-like 3
THOC6 THO complex 6
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
USP20 ubiquitin specific peptidase 20
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZNF124 zinc finger protein 124
ZNF302 zinc finger protein 302
ZNHIT2 zinc finger, HIT-type containing 2