pirenzepine-5872 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the pirenzepine-5872 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
ARHGAP26 Rho GTPase activating protein 26
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
BAHCC1 BAH domain and coiled-coil containing 1
C21ORF2 chromosome 21 open reading frame 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CADM3 cell adhesion molecule 3
CCDC85B coiled-coil domain containing 85B
CD52 CD52 molecule
CDK10 cyclin-dependent kinase 10
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CGA glycoprotein hormones, alpha polypeptide
CLEC2B C-type lectin domain family 2, member B
CLSPN claspin
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL11A2 collagen, type XI, alpha 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DHODH dihydroorotate dehydrogenase (quinone)
DNM3 dynamin 3
DSCAM Down syndrome cell adhesion molecule
ELP6 elongator acetyltransferase complex subunit 6
EPHA1 EPH receptor A1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAM205BP transmembrane protein C9orf144B pseudogene
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR3 fibroblast growth factor receptor 3
FLJ21369 uncharacterized protein FLJ21369
GCDH glutaryl-CoA dehydrogenase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC7 histone deacetylase 7
HIC2 hypermethylated in cancer 2
HPX hemopexin
IGFBP5 insulin-like growth factor binding protein 5
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL11 interleukin 11
ISYNA1 inositol-3-phosphate synthase 1
KCTD17 potassium channel tetramerization domain containing 17
KLHL25 kelch-like family member 25
KRIT1 KRIT1, ankyrin repeat containing
KRT17 keratin 17, type I
LMF2 lipase maturation factor 2
LMNA lamin A/C
LMOD1 leiomodin 1 (smooth muscle)
LRRK1 leucine-rich repeat kinase 1
MAP7 microtubule-associated protein 7
MCF2L MCF.2 cell line derived transforming sequence-like
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MT1F metallothionein 1F
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
N4BP2L1 NEDD4 binding protein 2-like 1
NCAPH2 non-SMC condensin II complex, subunit H2
NEUROD4 neuronal differentiation 4
NNAT neuronatin
PCDH7 protocadherin 7
PEX6 peroxisomal biogenesis factor 6
PGP phosphoglycolate phosphatase
PLD2 phospholipase D2
PLK3 polo-like kinase 3
PLVAP plasmalemma vesicle associated protein
PLXDC1 plexin domain containing 1
PLXNB3 plexin B3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRKCA protein kinase C, alpha
PROL1 proline rich, lacrimal 1
RAD54B RAD54 homolog B (S. cerevisiae)
RHOT2 ras homolog family member T2
RUFY3 RUN and FYVE domain containing 3
RWDD2A RWD domain containing 2A
SFTPC surfactant protein C
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SOX4 SRY (sex determining region Y)-box 4
STAC SH3 and cysteine rich domain
STS steroid sulfatase (microsomal), isozyme S
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TBC1D22A TBC1 domain family, member 22A
TBCD tubulin folding cofactor D
TH tyrosine hydroxylase
THRB thyroid hormone receptor, beta
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC6 transmembrane channel-like 6
TMEM206 transmembrane protein 206
TMPRSS2 transmembrane protease, serine 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
UBXN1 UBX domain protein 1
UTRN utrophin
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WEE1 WEE1 G2 checkpoint kinase
WIPF1 WAS/WASL interacting protein family, member 1
WNK1 WNK lysine deficient protein kinase 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAK1 BCL2-antagonist/killer 1
BCAS4 breast carcinoma amplified sequence 4
BIRC3 baculoviral IAP repeat containing 3
C11ORF73 chromosome 11 open reading frame 73
C16ORF59 chromosome 16 open reading frame 59
C4ORF19 chromosome 4 open reading frame 19
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEP97 centrosomal protein 97kDa
CLDN8 claudin 8
CLK2 CDC-like kinase 2
CNTNAP3B contactin associated protein-like 3B
CPA4 carboxypeptidase A4
CTAGE9 CTAGE family, member 9
DHRS11 dehydrogenase/reductase (SDR family) member 11
DIXDC1 DIX domain containing 1
DLL3 delta-like 3 (Drosophila)
EDC4 enhancer of mRNA decapping 4
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB2 GRB2-associated binding protein 2
GDAP2 ganglioside induced differentiation associated protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLCE glucuronic acid epimerase
GLT8D2 glycosyltransferase 8 domain containing 2
GPATCH3 G patch domain containing 3
GSR glutathione reductase
HIST1H3G histone cluster 1, H3g
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGB3P1 high mobility group box 3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
HS1BP3 HCLS1 binding protein 3
IL15RA interleukin 15 receptor, alpha
IREB2 iron-responsive element binding protein 2
KPTN kaptin (actin binding protein)
KRT31 keratin 31, type I
LOC100286895 cell division cycle 27 homolog pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC15 leucine rich repeat containing 15
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
NCSTN nicastrin
NDE1 nudE neurodevelopment protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPM3 nucleophosmin/nucleoplasmin 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML2A olfactomedin-like 2A
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PTGFR prostaglandin F receptor (FP)
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REEP4 receptor accessory protein 4
RGCC regulator of cell cycle
RNF121 ring finger protein 121
RPAP2 RNA polymerase II associated protein 2
RPL10L ribosomal protein L10-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SFMBT1 Scm-like with four mbt domains 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNC syncoilin, intermediate filament protein
SYTL2 synaptotagmin-like 2
TCTN1 tectonic family member 1
TESK2 testis-specific kinase 2
TFF2 trefoil factor 2
TMC7 transmembrane channel-like 7
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TMEM8A transmembrane protein 8A
TPK1 thiamin pyrophosphokinase 1
TRIM9 tripartite motif containing 9
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
USP20 ubiquitin specific peptidase 20
ZFAND3 zinc finger, AN1-type domain 3
ZNF10 zinc finger protein 10
ZNF254 zinc finger protein 254
ZNF408 zinc finger protein 408
ZNF442 zinc finger protein 442
ZNF629 zinc finger protein 629
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862