| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the piretanide-3567 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACVR1B | activin A receptor, type IB |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AGBL2 | ATP/GTP binding protein-like 2 |
| AIM2 | absent in melanoma 2 |
| AJAP1 | adherens junctions associated protein 1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARTN | artemin |
| CALD1 | caldesmon 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CES3 | carboxylesterase 3 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL5A2 | collagen, type V, alpha 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CPTP | ceramide-1-phosphate transfer protein |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DIO2 | deiodinase, iodothyronine, type II |
| EFHD2 | EF-hand domain family, member D2 |
| EGF | epidermal growth factor |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| ESR1 | estrogen receptor 1 |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FBXO31 | F-box protein 31 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GK | glycerol kinase |
| GK3P | glycerol kinase 3 pseudogene |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC11 | histone deacetylase 11 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOMER3 | homer scaffolding protein 3 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED16 | mediator complex subunit 16 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NABP1 | nucleic acid binding protein 1 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRL | neural retina leucine zipper |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTCRA | pre T-cell antigen receptor alpha |
| QSER1 | glutamine and serine rich 1 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| RPA4 | replication protein A4, 30kDa |
| RUNX1 | runt-related transcription factor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SYN3 | synapsin III |
| TKTL1 | transketolase-like 1 |
| TLK1 | tousled-like kinase 1 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM144 | transmembrane protein 144 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| ULBP2 | UL16 binding protein 2 |
| UPK3A | uroplakin 3A |
| VWA5A | von Willebrand factor A domain containing 5A |
| WWOX | WW domain containing oxidoreductase |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF442 | zinc finger protein 442 |
| ZNF589 | zinc finger protein 589 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALPK1 | alpha-kinase 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBC3 | BCL2 binding component 3 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBX8 | chromobox homolog 8 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CORO2A | coronin, actin binding protein, 2A |
| CRYL1 | crystallin, lambda 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNM1 | dynamin 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DSE | dermatan sulfate epimerase |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EMID1 | EMI domain containing 1 |
| ENO3 | enolase 3 (beta, muscle) |
| EPYC | epiphycan |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM204A | family with sequence similarity 204, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH3 | G patch domain containing 3 |
| GPR176 | G protein-coupled receptor 176 |
| GTPBP2 | GTP binding protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4F | histone cluster 1, H4f |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IRF9 | interferon regulatory factor 9 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0319L | KIAA0319-like |
| KIAA0355 | KIAA0355 |
| KIAA1107 | KIAA1107 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MEFV | Mediterranean fever |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTSS1L | metastasis suppressor 1-like |
| MYL5 | myosin, light chain 5, regulatory |
| NDRG4 | NDRG family member 4 |
| NEK11 | NIMA-related kinase 11 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PLXNA3 | plexin A3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS22 | protease, serine, 22 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB4B | RAB4B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RWDD3 | RWD domain containing 3 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCAI | suppressor of cancer cell invasion |
| SCARA3 | scavenger receptor class A, member 3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM120B | transmembrane protein 120B |
| USB1 | U6 snRNA biogenesis 1 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF205 | zinc finger protein 205 |
| ZNF324 | zinc finger protein 324 |
| ZNF423 | zinc finger protein 423 |
| ZNF532 | zinc finger protein 532 |
| ZNF652 | zinc finger protein 652 |
