| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the piretanide-4490 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AK2 | adenylate kinase 2 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARSD | arylsulfatase D |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATM | ATM serine/threonine kinase |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BMP4 | bone morphogenetic protein 4 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CDK13 | cyclin-dependent kinase 13 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL9A3 | collagen, type IX, alpha 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK5 | dedicator of cytokinesis 5 |
| DYM | dymeclin |
| ECE1 | endothelin converting enzyme 1 |
| EMID1 | EMI domain containing 1 |
| ESR1 | estrogen receptor 1 |
| ETV1 | ets variant 1 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLOT1 | flotillin 1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GK | glycerol kinase |
| GLB1L | galactosidase, beta 1-like |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPM6A | glycoprotein M6A |
| GPR15 | G protein-coupled receptor 15 |
| GPR85 | G protein-coupled receptor 85 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IL22 | interleukin 22 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0319L | KIAA0319-like |
| KLHL22 | kelch-like family member 22 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MLXIP | MLX interacting protein |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCOR2 | nuclear receptor corepressor 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOX1 | NADPH oxidase 1 |
| NPR2 | natriuretic peptide receptor 2 |
| OMG | oligodendrocyte myelin glycoprotein |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU2F3 | POU class 2 homeobox 3 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRDX2 | peroxiredoxin 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB40B | RAB40B, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| T | T, brachyury homolog (mouse) |
| TAOK2 | TAO kinase 2 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TLK1 | tousled-like kinase 1 |
| TRIM66 | tripartite motif containing 66 |
| TSPAN32 | tetraspanin 32 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR62 | WD repeat domain 62 |
| WDR78 | WD repeat domain 78 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XAF1 | XIAP associated factor 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF235 | zinc finger protein 235 |
| ZNF510 | zinc finger protein 510 |
| ZNF652 | zinc finger protein 652 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AK5 | adenylate kinase 5 |
| ARF5 | ADP-ribosylation factor 5 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BTC | betacellulin |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CDHR2 | cadherin-related family member 2 |
| CPNE7 | copine VII |
| CRYGC | crystallin, gamma C |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DMTN | dematin actin binding protein |
| DNM3 | dynamin 3 |
| EFNA3 | ephrin-A3 |
| EGF | epidermal growth factor |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELMO3 | engulfment and cell motility 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FBXO2 | F-box protein 2 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGL1 | fibrinogen-like 1 |
| FMO4 | flavin containing monooxygenase 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAS2 | growth arrest-specific 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| HPN | hepsin |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFT54 | intraflagellar transport 54 |
| IL11RA | interleukin 11 receptor, alpha |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIFC3 | kinesin family member C3 |
| KLHL36 | kelch-like family member 36 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC6 | leucine rich repeat containing 6 |
| LY86 | lymphocyte antigen 86 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MGP | matrix Gla protein |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MUC3A | mucin 3A, cell surface associated |
| MYL5 | myosin, light chain 5, regulatory |
| NINL | ninein-like |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRTN | neurturin |
| OLFML3 | olfactomedin-like 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PER3 | period circadian clock 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRSS22 | protease, serine, 22 |
| PTGFR | prostaglandin F receptor (FP) |
| RBM38 | RNA binding motif protein 38 |
| SCARA3 | scavenger receptor class A, member 3 |
| SELL | selectin L |
| SLC12A8 | solute carrier family 12, member 8 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSBP3 | single stranded DNA binding protein 3 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TCTN2 | tectonic family member 2 |
| TEX15 | testis expressed 15 |
| TMEM8B | transmembrane protein 8B |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBB2B | tubulin, beta 2B class IIb |
| YY2 | YY2 transcription factor |
| ZNF197 | zinc finger protein 197 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
