| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the piretanide-6828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APOL2 | apolipoprotein L, 2 |
| ARTN | artemin |
| ATP11A | ATPase, class VI, type 11A |
| ATP9A | ATPase, class II, type 9A |
| BFSP2 | beaded filament structural protein 2, phakinin |
| BMP6 | bone morphogenetic protein 6 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCNK | cyclin K |
| CD70 | CD70 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CLCA1 | chloride channel accessory 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK4 | docking protein 4 |
| DUX1 | double homeobox 1 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EXOSC1 | exosome component 1 |
| FAM214B | family with sequence similarity 214, member B |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGA | fibrinogen alpha chain |
| FLOT1 | flotillin 1 |
| FRMD1 | FERM domain containing 1 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GAS7 | growth arrest-specific 7 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GP1BB | glycoprotein Ib (platelet), beta polypeptide |
| GPR143 | G protein-coupled receptor 143 |
| GPR176 | G protein-coupled receptor 176 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL36G | interleukin 36, gamma |
| IL5RA | interleukin 5 receptor, alpha |
| IL6R | interleukin 6 receptor |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIF21B | kinesin family member 21B |
| KLF12 | Kruppel-like factor 12 |
| KLF13 | Kruppel-like factor 13 |
| KRT17 | keratin 17, type I |
| LEPR | leptin receptor |
| LIN7A | lin-7 homolog A (C. elegans) |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC75B | leucine rich repeat containing 75B |
| MAPK14 | mitogen-activated protein kinase 14 |
| MRC2 | mannose receptor, C type 2 |
| MTA1 | metastasis associated 1 |
| MUC8 | mucin 8 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO9B | myosin IXB |
| MYOZ1 | myozenin 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLXNC1 | plexin C1 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PURA | purine-rich element binding protein A |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAI2 | retinoic acid induced 2 |
| RANBP1 | RAN binding protein 1 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM12 | RNA binding motif protein 12 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RXRB | retinoid X receptor, beta |
| SCAMP1 | secretory carrier membrane protein 1 |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| STK17B | serine/threonine kinase 17b |
| STK38 | serine/threonine kinase 38 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX14 | testis expressed 14 |
| TPSAB1 | tryptase alpha/beta 1 |
| WDR33 | WD repeat domain 33 |
| WSCD1 | WSC domain containing 1 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A4GALT | alpha 1,4-galactosyltransferase |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC69 | coiled-coil domain containing 69 |
| CD82 | CD82 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CORO7 | coronin 7 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNM1 | dynamin 1 |
| DOC2A | double C2-like domains, alpha |
| DYSF | dysferlin |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FAM46C | family with sequence similarity 46, member C |
| FILIP1L | filamin A interacting protein 1-like |
| FMOD | fibromodulin |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GTPBP2 | GTP binding protein 2 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H2BI | histone cluster 1, H2bi |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF1 | interferon regulatory factor 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0556 | KIAA0556 |
| KIF16B | kinesin family member 16B |
| LOC729164 | hCG1732469 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MPI | mannose phosphate isomerase |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCBP3 | poly(rC) binding protein 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLD3 | phospholipase D family, member 3 |
| PODNL1 | podocan-like 1 |
| PODXL2 | podocalyxin-like 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RGS2 | regulator of G-protein signaling 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| ST5 | suppression of tumorigenicity 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TBX19 | T-box 19 |
| TMEM209 | transmembrane protein 209 |
| TMEM212 | transmembrane protein 212 |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN1 | tetraspanin 1 |
| TUBG2 | tubulin, gamma 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VAX2 | ventral anterior homeobox 2 |
| VGF | VGF nerve growth factor inducible |
| WDR62 | WD repeat domain 62 |
| WDR91 | WD repeat domain 91 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF552 | zinc finger protein 552 |
