piribedil-2951 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the piribedil-2951 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMPD3 adenosine monophosphate deaminase 3
AREG amphiregulin
BBS9 Bardet-Biedl syndrome 9
C1ORF95 chromosome 1 open reading frame 95
CD300C CD300c molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD6 CD6 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CELP carboxyl ester lipase pseudogene
CLIP2 CAP-GLY domain containing linker protein 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL9A3 collagen, type IX, alpha 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTC1 CTS telomere maintenance complex component 1
DMC1 DNA meiotic recombinase 1
DOCK6 dedicator of cytokinesis 6
DTX4 deltex 4, E3 ubiquitin ligase
DVL1 dishevelled segment polarity protein 1
EGR1 early growth response 1
FCMR Fc fragment of IgM receptor
FGL1 fibrinogen-like 1
FHL1 four and a half LIM domains 1
FLT1 fms-related tyrosine kinase 1
FSD1 fibronectin type III and SPRY domain containing 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GPR35 G protein-coupled receptor 35
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRIK5 glutamate receptor, ionotropic, kainate 5
HAB1 B1 for mucin
HEG1 heart development protein with EGF-like domains 1
IGFBP5 insulin-like growth factor binding protein 5
ISG20 interferon stimulated exonuclease gene 20kDa
ITPKC inositol-trisphosphate 3-kinase C
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IZUMO4 IZUMO family member 4
KCTD2 potassium channel tetramerization domain containing 2
KDM8 lysine (K)-specific demethylase 8
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MOB3B MOB kinase activator 3B
MPZ myelin protein zero
MR1 major histocompatibility complex, class I-related
MREG melanoregulin
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEB nebulin
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM7 PDZ and LIM domain 7 (enigma)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCG1 phospholipase C, gamma 1
PLCL2 phospholipase C-like 2
PODNL1 podocan-like 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRF1 perforin 1 (pore forming protein)
RAB3D RAB3D, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOD ras homolog family member D
RPL13P5 ribosomal protein L13 pseudogene 5
RPL18 ribosomal protein L18
RPS3A ribosomal protein S3A
RRBP1 ribosome binding protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAPER S-phase cyclin A-associated protein in the ER
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A44 solute carrier family 25, member 44
SNX13 sorting nexin 13
SOX13 SRY (sex determining region Y)-box 13
SP140 SP140 nuclear body protein
SPTAN1 spectrin, alpha, non-erythrocytic 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STK11 serine/threonine kinase 11
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TGFB3 transforming growth factor, beta 3
THAP3 THAP domain containing, apoptosis associated protein 3
THTPA thiamine triphosphatase
TLE3 transducin-like enhancer of split 3
TMEM63A transmembrane protein 63A
TTLL3 tubulin tyrosine ligase-like family member 3
UPP1 uridine phosphorylase 1
USP20 ubiquitin specific peptidase 20
WAS Wiskott-Aldrich syndrome
WWC1 WW and C2 domain containing 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF280B zinc finger protein 280B
ZNF337 zinc finger protein 337
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACP2 acid phosphatase 2, lysosomal
AKTIP AKT interacting protein
BATF basic leucine zipper transcription factor, ATF-like
BEX1 brain expressed, X-linked 1
BRIX1 BRX1, biogenesis of ribosomes
C12ORF29 chromosome 12 open reading frame 29
C17ORF75 chromosome 17 open reading frame 75
C21ORF59 chromosome 21 open reading frame 59
CARKD carbohydrate kinase domain containing
CBR1 carbonyl reductase 1
CBX6 chromobox homolog 6
CCDC25 coiled-coil domain containing 25
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHM choroideremia (Rab escort protein 1)
CIDEB cell death-inducing DFFA-like effector b
COQ4 coenzyme Q4
CTSL cathepsin L
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIXDC1 DIX domain containing 1
E2F6 E2F transcription factor 6
EBNA1BP2 EBNA1 binding protein 2
FAM206A family with sequence similarity 206, member A
FHIT fragile histidine triad
GAMT guanidinoacetate N-methyltransferase
GLTP glycolipid transfer protein
GMPPB GDP-mannose pyrophosphorylase B
GPR63 G protein-coupled receptor 63
GRAMD1B GRAM domain containing 1B
GRB2 growth factor receptor-bound protein 2
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HMGB3 high mobility group box 3
HPS6 Hermansky-Pudlak syndrome 6
IPO8 importin 8
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
LAMP5 lysosomal-associated membrane protein family, member 5
LINC00115 long intergenic non-protein coding RNA 115
LRP3 low density lipoprotein receptor-related protein 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL8 methyltransferase like 8
MRPS34 mitochondrial ribosomal protein S34
MYBBP1A MYB binding protein (P160) 1a
NFS1 NFS1 cysteine desulfurase
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOL6 nucleolar protein 6 (RNA-associated)
PARG poly (ADP-ribose) glycohydrolase
PARL presenilin associated, rhomboid-like
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITRM1 pitrilysin metallopeptidase 1
POGLUT1 protein O-glucosyltransferase 1
PPAN peter pan homolog (Drosophila)
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAT1 phosphoserine aminotransferase 1
PTGES2 prostaglandin E synthase 2
RAB1B RAB1B, member RAS oncogene family
RBM28 RNA binding motif protein 28
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REEP4 receptor accessory protein 4
RNF2 ring finger protein 2
RPIA ribose 5-phosphate isomerase A
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RWDD2A RWD domain containing 2A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCRIB scribbled planar cell polarity protein
SDCCAG3 serologically defined colon cancer antigen 3
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SGMS1 sphingomyelin synthase 1
SHPK sedoheptulokinase
SP1 Sp1 transcription factor
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TCEA2 transcription elongation factor A (SII), 2
TERT telomerase reverse transcriptase
TESC tescalcin
TMEM177 transmembrane protein 177
TMEM183A transmembrane protein 183A
TMEM184C transmembrane protein 184C
TMEM230 transmembrane protein 230
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UBP1 upstream binding protein 1 (LBP-1a)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
YY2 YY2 transcription factor
ZBED8 zinc finger, BED-type containing 8
ZFP30 ZFP30 zinc finger protein
ZNF468 zinc finger protein 468
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787