piribedil-3512 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the piribedil-3512 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM19 ADAM metallopeptidase domain 19
ANP32A-IT1 ANP32A intronic transcript 1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARHGAP1 Rho GTPase activating protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARNT aryl hydrocarbon receptor nuclear translocator
ATAT1 alpha tubulin acetyltransferase 1
ATF6B activating transcription factor 6 beta
BMP15 bone morphogenetic protein 15
C21ORF2 chromosome 21 open reading frame 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CCDC57 coiled-coil domain containing 57
CCR2 chemokine (C-C motif) receptor 2
CCRL2 chemokine (C-C motif) receptor-like 2
CDC42 cell division cycle 42
CDK19 cyclin-dependent kinase 19
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDON cell adhesion associated, oncogene regulated
CES3 carboxylesterase 3
CFHR4 complement factor H-related 4
CLIC5 chloride intracellular channel 5
DMWD dystrophia myotonica, WD repeat containing
DOCK5 dedicator of cytokinesis 5
DOPEY2 dopey family member 2
DUSP6 dual specificity phosphatase 6
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EXPH5 exophilin 5
FAM131A family with sequence similarity 131, member A
FBXO2 F-box protein 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPM6B glycoprotein M6B
GPR22 G protein-coupled receptor 22
GREB1 growth regulation by estrogen in breast cancer 1
GRM8 glutamate receptor, metabotropic 8
HGD homogentisate 1,2-dioxygenase
HIST1H2BN histone cluster 1, H2bn
KHSRP KH-type splicing regulatory protein
KIAA1107 KIAA1107
LIMK2 LIM domain kinase 2
LMTK1 lemur tail kinase 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC8B leucine rich repeat containing 8 family, member B
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTSS1L metastasis suppressor 1-like
MYCNOS MYCN opposite strand
N4BP1 NEDD4 binding protein 1
NRF1 nuclear respiratory factor 1
OLFML2B olfactomedin-like 2B
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCD1 phospholipase C, delta 1
PLCH1 phospholipase C, eta 1
PLIN2 perilipin 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RAB11B RAB11B, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RPS3A ribosomal protein S3A
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERGEF secretion regulating guanine nucleotide exchange factor
SH3PXD2A SH3 and PX domains 2A
SKIL SKI-like proto-oncogene
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SMR3A submaxillary gland androgen regulated protein 3A
SOSTDC1 sclerostin domain containing 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT5A signal transducer and activator of transcription 5A
STRN3 striatin, calmodulin binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TGM2 transglutaminase 2
THBS4 thrombospondin 4
THPO thrombopoietin
TIAM2 T-cell lymphoma invasion and metastasis 2
TRAK1 trafficking protein, kinesin binding 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
UBQLN4 ubiquilin 4
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WSCD1 WSC domain containing 1
ZER1 zyg-11 related, cell cycle regulator
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABI3BP ABI family, member 3 (NESH) binding protein
ADAM15 ADAM metallopeptidase domain 15
AHDC1 AT hook, DNA binding motif, containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
BAK1 BCL2-antagonist/killer 1
BTBD2 BTB (POZ) domain containing 2
BTBD7 BTB (POZ) domain containing 7
BTF3P12 basic transcription factor 3 pseudogene 12
CAPG capping protein (actin filament), gelsolin-like
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLK1 CDC-like kinase 1
COQ4 coenzyme Q4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
ECSIT ECSIT signalling integrator
EFHD2 EF-hand domain family, member D2
EFNA4 ephrin-A4
FAM46C family with sequence similarity 46, member C
FAM86B1 family with sequence similarity 86, member B1
FBXL6 F-box and leucine-rich repeat protein 6
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALK1 galactokinase 1
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GID4 GID complex subunit 4
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL17RA interleukin 17 receptor A
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
LARP6 La ribonucleoprotein domain family, member 6
LHX6 LIM homeobox 6
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5L low density lipoprotein receptor-related protein 5-like
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MBIP MAP3K12 binding inhibitory protein 1
MCOLN3 mucolipin 3
MFAP2 microfibrillar-associated protein 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGC12488
MORC4 MORC family CW-type zinc finger 4
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NOL12 nucleolar protein 12
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM2 PDZ and LIM domain 2 (mystique)
PGP phosphoglycolate phosphatase
PHF21A PHD finger protein 21A
PLD3 phospholipase D family, member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRSS22 protease, serine, 22
PTCD2 pentatricopeptide repeat domain 2
PTDSS2 phosphatidylserine synthase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPRU protein tyrosine phosphatase, receptor type, U
RASA2 RAS p21 protein activator 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFTN1 raftlin, lipid raft linker 1
RNF121 ring finger protein 121
RNF216 ring finger protein 216
RPGRIP1L RPGRIP1-like
RPH3AL rabphilin 3A-like (without C2 domains)
RUSC2 RUN and SH3 domain containing 2
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SKI SKI proto-oncogene
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX5 syntaxin 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAOK1 TAO kinase 1
TMEM62 transmembrane protein 62
TMSB15A thymosin beta 15a
TNK1 tyrosine kinase, non-receptor, 1
TOM1 target of myb1 (chicken)
TRAIP TRAF interacting protein
USB1 U6 snRNA biogenesis 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF532 zinc finger protein 532