Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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191 genes differentially expressed following the pirinixic acid-368 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAP1 | ArfGAP with dual PH domains 1 |
ADIRF | adipogenesis regulatory factor |
ALAD | aminolevulinate dehydratase |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
ARFRP1 | ADP-ribosylation factor related protein 1 |
ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
ATF6 | activating transcription factor 6 |
ATP13A2 | ATPase type 13A2 |
ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
ATR | ATR serine/threonine kinase |
B3GAT3 | beta-1,3-glucuronyltransferase 3 |
BHLHE40 | basic helix-loop-helix family, member e40 |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
BRCA1 | breast cancer 1, early onset |
BTBD2 | BTB (POZ) domain containing 2 |
BTD | biotinidase |
CEP170 | centrosomal protein 170kDa |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
COBL | cordon-bleu WH2 repeat protein |
CTC1 | CTS telomere maintenance complex component 1 |
DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
DHPS | deoxyhypusine synthase |
DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
EMC1 | ER membrane protein complex subunit 1 |
ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
EPHA4 | EPH receptor A4 |
EXOSC9 | exosome component 9 |
FAM114A2 | family with sequence similarity 114, member A2 |
FAM153A | family with sequence similarity 153, member A |
FANCA | Fanconi anemia, complementation group A |
FANCF | Fanconi anemia, complementation group F |
FASTK | Fas-activated serine/threonine kinase |
FXR2 | fragile X mental retardation, autosomal homolog 2 |
GAS7 | growth arrest-specific 7 |
GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
GSTM4 | glutathione S-transferase mu 4 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HIST1H4J | histone cluster 1, H4j |
HMGA1 | high mobility group AT-hook 1 |
HSPA4 | heat shock 70kDa protein 4 |
HUS1 | HUS1 checkpoint homolog (S. pombe) |
IL19 | interleukin 19 |
KCTD2 | potassium channel tetramerization domain containing 2 |
MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
MAPK8 | mitogen-activated protein kinase 8 |
MARC1 | mitochondrial amidoxime reducing component 1 |
MPPE1 | metallophosphoesterase 1 |
MPV17 | MpV17 mitochondrial inner membrane protein |
MRPL35 | mitochondrial ribosomal protein L35 |
MT1HL1 | metallothionein 1H-like 1 |
MXD4 | MAX dimerization protein 4 |
NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
NUP210 | nucleoporin 210kDa |
NUPL2 | nucleoporin like 2 |
PCDHB3 | protocadherin beta 3 |
PCGF1 | polycomb group ring finger 1 |
PEX11A | peroxisomal biogenesis factor 11 alpha |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PLCD1 | phospholipase C, delta 1 |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
PPARD | peroxisome proliferator-activated receptor delta |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
PRMT7 | protein arginine methyltransferase 7 |
PTEN | phosphatase and tensin homolog |
PVR | poliovirus receptor |
RAB3D | RAB3D, member RAS oncogene family |
RAB8B | RAB8B, member RAS oncogene family |
RANBP10 | RAN binding protein 10 |
RBM10 | RNA binding motif protein 10 |
RPS11 | ribosomal protein S11 |
RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
RUNX1 | runt-related transcription factor 1 |
SBF1 | SET binding factor 1 |
SBNO2 | strawberry notch homolog 2 (Drosophila) |
SGSM3 | small G protein signaling modulator 3 |
SIRPA | signal-regulatory protein alpha |
SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
SURF2 | surfeit 2 |
SZRD1 | SUZ RNA binding domain containing 1 |
TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
TCEA2 | transcription elongation factor A (SII), 2 |
TMPRSS2 | transmembrane protease, serine 2 |
TNK2 | tyrosine kinase, non-receptor, 2 |
TRIO | trio Rho guanine nucleotide exchange factor |
TSSC4 | tumor suppressing subtransferable candidate 4 |
TXNRD2 | thioredoxin reductase 2 |
WDR13 | WD repeat domain 13 |
WDR46 | WD repeat domain 46 |
WWTR1 | WW domain containing transcription regulator 1 |
Symbol | Name |
---|---|
A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
ACPP | acid phosphatase, prostate |
ADAM23 | ADAM metallopeptidase domain 23 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
BNC1 | basonuclin 1 |
CAMKV | CaM kinase-like vesicle-associated |
CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
CBX8 | chromobox homolog 8 |
CCDC176 | coiled-coil domain containing 176 |
CCKBR | cholecystokinin B receptor |
CD101 | CD101 molecule |
CD2 | CD2 molecule |
CD53 | CD53 molecule |
CDH22 | cadherin 22, type 2 |
CEP41 | centrosomal protein 41kDa |
CHRM2 | cholinergic receptor, muscarinic 2 |
CIDEB | cell death-inducing DFFA-like effector b |
CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
CNTNAP1 | contactin associated protein 1 |
CRHBP | corticotropin releasing hormone binding protein |
CTNNA3 | catenin (cadherin-associated protein), alpha 3 |
CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
DENND1C | DENN/MADD domain containing 1C |
ECE2 | endothelin converting enzyme 2 |
F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
GLRA2 | glycine receptor, alpha 2 |
GNAT3 | guanine nucleotide binding protein, alpha transducing 3 |
GUCA2A | guanylate cyclase activator 2A (guanylin) |
H2AFY2 | H2A histone family, member Y2 |
HAND1 | heart and neural crest derivatives expressed 1 |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AB | histone cluster 1, H2ab |
HMGA2 | high mobility group AT-hook 2 |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
IL10RA | interleukin 10 receptor, alpha |
IL21 | interleukin 21 |
IQCA1 | IQ motif containing with AAA domain 1 |
KIAA0509 | uncharacterized LOC57242 |
KIAA1549L | KIAA1549-like |
KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
KLHL1 | kelch-like family member 1 |
KLHL3 | kelch-like family member 3 |
LEFTY1 | left-right determination factor 1 |
LGALS13 | lectin, galactoside-binding, soluble, 13 |
LIN28A | lin-28 homolog A (C. elegans) |
LINC00339 | long intergenic non-protein coding RNA 339 |
LUZP4 | leucine zipper protein 4 |
MED31 | mediator complex subunit 31 |
MFSD11 | major facilitator superfamily domain containing 11 |
MIP | major intrinsic protein of lens fiber |
MMP27 | matrix metallopeptidase 27 |
MMP7 | matrix metallopeptidase 7 |
MOXD1 | monooxygenase, DBH-like 1 |
MRPL41 | mitochondrial ribosomal protein L41 |
MT4 | metallothionein 4 |
MYOZ3 | myozenin 3 |
NXPH3 | neurexophilin 3 |
OPRK1 | opioid receptor, kappa 1 |
PCDH17 | protocadherin 17 |
PDZD7 | PDZ domain containing 7 |
PHOX2A | paired-like homeobox 2a |
PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
POPDC2 | popeye domain containing 2 |
POPDC3 | popeye domain containing 3 |
PRKG2 | protein kinase, cGMP-dependent, type II |
REG1B | regenerating islet-derived 1 beta |
RRH | retinal pigment epithelium-derived rhodopsin homolog |
S100A1 | S100 calcium binding protein A1 |
S100A2 | S100 calcium binding protein A2 |
SCARA3 | scavenger receptor class A, member 3 |
SCNN1B | sodium channel, non voltage gated 1 beta subunit |
SDK2 | sidekick cell adhesion molecule 2 |
SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 |
SLC24A2 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
STAT4 | signal transducer and activator of transcription 4 |
STAT5A | signal transducer and activator of transcription 5A |
SYNGR4 | synaptogyrin 4 |
SYNPO | synaptopodin |
THBS2 | thrombospondin 2 |
TMEM176A | transmembrane protein 176A |
TMEM40 | transmembrane protein 40 |
TMEM50A | transmembrane protein 50A |
TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
VSIG4 | V-set and immunoglobulin domain containing 4 |
ZBTB39 | zinc finger and BTB domain containing 39 |
ZNF430 | zinc finger protein 430 |