| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pirinixic acid-487 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM2 | adrenomedullin 2 |
| AGRN | agrin |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CAV3 | caveolin 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CD2AP | CD2-associated protein |
| CD6 | CD6 molecule |
| CDC42 | cell division cycle 42 |
| CES3 | carboxylesterase 3 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CRYAB | crystallin, alpha B |
| CSN2 | casein beta |
| DLEC1 | deleted in lung and esophageal cancer 1 |
| DOC2B | double C2-like domains, beta |
| DRP2 | dystrophin related protein 2 |
| DUSP22 | dual specificity phosphatase 22 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| FLNC | filamin C, gamma |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) |
| IFI35 | interferon-induced protein 35 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL16 | interleukin 16 |
| IL7R | interleukin 7 receptor |
| KLHL25 | kelch-like family member 25 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MEP1B | meprin A, beta |
| MOB3B | MOB kinase activator 3B |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MXD4 | MAX dimerization protein 4 |
| MXRA5 | matrix-remodelling associated 5 |
| MYL10 | myosin, light chain 10, regulatory |
| NDRG2 | NDRG family member 2 |
| OCLM | oculomedin |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| PAX8 | paired box 8 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP | prolactin-induced protein |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RARG | retinoic acid receptor, gamma |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPLP2 | ribosomal protein, large, P2 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| SH3D21 | SH3 domain containing 21 |
| SIX6 | SIX homeobox 6 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMO | smoothened, frizzled class receptor |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNGR1 | synaptogyrin 1 |
| TBL2 | transducin (beta)-like 2 |
| TCF3 | transcription factor 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TP63 | tumor protein p63 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| TWF1 | twinfilin actin binding protein 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WSCD1 | WSC domain containing 1 |
| ZMYND10 | zinc finger, MYND-type containing 10 |
| ZNF35 | zinc finger protein 35 |
| Symbol | Name |
|---|---|
| ABT1 | activator of basal transcription 1 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| AXIN1 | axin 1 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHN1 | chimerin 1 |
| CIC | capicua transcriptional repressor |
| CLCA1 | chloride channel accessory 1 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CNTN1 | contactin 1 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| COMMD10 | COMM domain containing 10 |
| COPS7B | COP9 signalosome subunit 7B |
| CRLF3 | cytokine receptor-like factor 3 |
| CROT | carnitine O-octanoyltransferase |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DENND4C | DENN/MADD domain containing 4C |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DPEP1 | dipeptidase 1 (renal) |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| EXOC6B | exocyst complex component 6B |
| FAM189B | family with sequence similarity 189, member B |
| FASTKD3 | FAST kinase domains 3 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOSL1 | FOS-like antigen 1 |
| FOXD1 | forkhead box D1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GP9 | glycoprotein IX (platelet) |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMG20A | high mobility group 20A |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL15RA | interleukin 15 receptor, alpha |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JAM3 | junctional adhesion molecule 3 |
| JOSD1 | Josephin domain containing 1 |
| KIF5A | kinesin family member 5A |
| KLHL28 | kelch-like family member 28 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGMN | legumain |
| LOC440792 | proline dehydrogenase (oxidase) 1 pseudogene |
| MON1B | MON1 secretory trafficking family member B |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MT4 | metallothionein 4 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NABP2 | nucleic acid binding protein 2 |
| NADSYN1 | NAD synthetase 1 |
| NCS1 | neuronal calcium sensor 1 |
| NNAT | neuronatin |
| NRSN2 | neurensin 2 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCD1 | phospholipase C, delta 1 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PLIN3 | perilipin 3 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRDM14 | PR domain containing 14 |
| PRND | prion protein 2 (dublet) |
| PRPF39 | pre-mRNA processing factor 39 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RANBP6 | RAN binding protein 6 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNF11 | ring finger protein 11 |
| RNF141 | ring finger protein 141 |
| RPAP3 | RNA polymerase II associated protein 3 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TEX13B | testis expressed 13B |
| TKFC | triokinase/FMN cyclase |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TTI1 | TELO2 interacting protein 1 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF16 | zinc finger protein 16 |
| ZNF586 | zinc finger protein 586 |
