pirlindole-5497 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the pirlindole-5497 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AGMAT agmatine ureohydrolase (agmatinase)
AK2 adenylate kinase 2
AKAP6 A kinase (PRKA) anchor protein 6
ANGPTL2 angiopoietin-like 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BMP15 bone morphogenetic protein 15
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM4 cell adhesion molecule 4
CCDC132 coiled-coil domain containing 132
CCDC93 coiled-coil domain containing 93
CCP110 centriolar coiled coil protein 110kDa
CD53 CD53 molecule
CDH18 cadherin 18, type 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CHAT choline O-acetyltransferase
CLDN17 claudin 17
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
CRTAC1 cartilage acidic protein 1
CRYGC crystallin, gamma C
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUOX2 dual oxidase 2
DUSP13 dual specificity phosphatase 13
EDRF1 erythroid differentiation regulatory factor 1
EGR1 early growth response 1
EHD1 EH-domain containing 1
ELL2 elongation factor, RNA polymerase II, 2
EPX eosinophil peroxidase
ETNK2 ethanolamine kinase 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLJ42627 uncharacterized LOC645644
FNTB farnesyltransferase, CAAX box, beta
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD9 frizzled class receptor 9
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GK glycerol kinase
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP5 glycoprotein V (platelet)
GSAP gamma-secretase activating protein
GSTA1 glutathione S-transferase alpha 1
HIST1H2AL histone cluster 1, H2al
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCTD7 potassium channel tetramerization domain containing 7
KLHL22 kelch-like family member 22
KLK13 kallikrein-related peptidase 13
KRT2 keratin 2, type II
LENEP lens epithelial protein
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAN2A2 mannosidase, alpha, class 2A, member 2
MAPK14 mitogen-activated protein kinase 14
MBTPS2 membrane-bound transcription factor peptidase, site 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOCS1 molybdenum cofactor synthesis 1
N4BP3 NEDD4 binding protein 3
NCOA2 nuclear receptor coactivator 2
NOX1 NADPH oxidase 1
NPR3 natriuretic peptide receptor 3
PAQR5 progestin and adipoQ receptor family member V
PDLIM5 PDZ and LIM domain 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLD3 phospholipase D family, member 3
POU2F3 POU class 2 homeobox 3
PRKCB protein kinase C, beta
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRO protein tyrosine phosphatase, receptor type, O
QTRT1 queuine tRNA-ribosyltransferase 1
RGSL1 regulator of G-protein signaling like 1
RIMS2 regulating synaptic membrane exocytosis 2
SELL selectin L
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLN sarcolipin
STAT5B signal transducer and activator of transcription 5B
TAC3 tachykinin 3
TBC1D5 TBC1 domain family, member 5
TEX15 testis expressed 15
TMPRSS3 transmembrane protease, serine 3
TRPC1 transient receptor potential cation channel, subfamily C, member 1
VARS valyl-tRNA synthetase
VAV2 vav 2 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VN1R1 vomeronasal 1 receptor 1
WDR59 WD repeat domain 59
WDR78 WD repeat domain 78
ZIC3 Zic family member 3
ZNF614 zinc finger protein 614
ZNF821 zinc finger protein 821
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ANXA1 annexin A1
ASB9 ankyrin repeat and SOCS box containing 9
BRPF1 bromodomain and PHD finger containing, 1
CCDC85C coiled-coil domain containing 85C
CDK20 cyclin-dependent kinase 20
CDKN2AIP CDKN2A interacting protein
CEP131 centrosomal protein 131kDa
CHKB choline kinase beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CTNNBIP1 catenin, beta interacting protein 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCP1A decapping mRNA 1A
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAL4 dynein, axonemal, light chain 4
EDC3 enhancer of mRNA decapping 3
EPPK1 epiplakin 1
EVPL envoplakin
F2R coagulation factor II (thrombin) receptor
FAM204A family with sequence similarity 204, member A
FBRS fibrosin
FGGY FGGY carbohydrate kinase domain containing
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSD1 fibronectin type III and SPRY domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GRAMD4 GRAM domain containing 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HPN hepsin
HSPA2 heat shock 70kDa protein 2
INSIG2 insulin induced gene 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0753 KIAA0753
KLC2 kinesin light chain 2
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
METTL2B methyltransferase like 2B
MGC12488
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL5 myosin, light chain 5, regulatory
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPFFR1 neuropeptide FF receptor 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUD3 OTU deubiquitinase 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHKA1 phosphorylase kinase, alpha 1 (muscle)
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPAP2 RNA polymerase II associated protein 2
SCAMP5 secretory carrier membrane protein 5
SH3BGR SH3 domain binding glutamate-rich protein
SHPK sedoheptulokinase
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNUPN snurportin 1
SREK1IP1 SREK1-interacting protein 1
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
THBS3 thrombospondin 3
TLR5 toll-like receptor 5
TMEM104 transmembrane protein 104
TPRA1 transmembrane protein, adipocyte asscociated 1
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
UBE2Z ubiquitin-conjugating enzyme E2Z
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF211 zinc finger protein 211
ZNF273 zinc finger protein 273
ZNF34 zinc finger protein 34
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF816 zinc finger protein 816
ZSCAN9 zinc finger and SCAN domain containing 9