piromidic acid-3335 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the piromidic acid-3335 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AUTS2 autism susceptibility candidate 2
BTN3A1 butyrophilin, subfamily 3, member A1
C1S complement component 1, s subcomponent
C21ORF2 chromosome 21 open reading frame 2
C6ORF10 chromosome 6 open reading frame 10
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC64 coiled-coil domain containing 64
CD70 CD70 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK14 cyclin-dependent kinase 14
CNN1 calponin 1, basic, smooth muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL19A1 collagen, type XIX, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTSZ cathepsin Z
CYTH4 cytohesin 4
DGKG diacylglycerol kinase, gamma 90kDa
DOCK6 dedicator of cytokinesis 6
DOK4 docking protein 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELL elongation factor RNA polymerase II
EXOSC1 exosome component 1
EZR ezrin
FGF18 fibroblast growth factor 18
FKBP10 FK506 binding protein 10, 65 kDa
FRMD8 FERM domain containing 8
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GM2A GM2 ganglioside activator
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPC1 glypican 1
GPR3 G protein-coupled receptor 3
GRM1 glutamate receptor, metabotropic 1
GSTA3 glutathione S-transferase alpha 3
HAO2 hydroxyacid oxidase 2 (long chain)
HMOX1 heme oxygenase 1
ING1 inhibitor of growth family, member 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAG1 jagged 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA1109 KIAA1109
LAMB4 laminin, beta 4
LATS1 large tumor suppressor kinase 1
LOC647070 uncharacterized LOC647070
LPL lipoprotein lipase
MAOB monoamine oxidase B
MED25 mediator complex subunit 25
MOCS1 molybdenum cofactor synthesis 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYT1 myelin transcription factor 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD4 neuronal differentiation 4
NME5 NME/NM23 family member 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUP188 nucleoporin 188kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
OXCT2 3-oxoacid CoA transferase 2
PAPOLG poly(A) polymerase gamma
PCBP3 poly(rC) binding protein 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE9A phosphodiesterase 9A
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCH1 phospholipase C, eta 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PSORS1C1 psoriasis susceptibility 1 candidate 1
PVR poliovirus receptor
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RANBP3 RAN binding protein 3
RFPL3 ret finger protein-like 3
RHEB Ras homolog enriched in brain
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RTCA RNA 3'-terminal phosphate cyclase
RUNX1 runt-related transcription factor 1
SAA3P serum amyloid A3 pseudogene
SAG S-antigen; retina and pineal gland (arrestin)
SDS serine dehydratase
SECTM1 secreted and transmembrane 1
SIRT5 sirtuin 5
SP1 Sp1 transcription factor
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF7 serine/arginine-rich splicing factor 7
STS steroid sulfatase (microsomal), isozyme S
TBX3 T-box 3
TH tyrosine hydroxylase
TMEM63A transmembrane protein 63A
TRD T cell receptor delta locus
WDR55 WD repeat domain 55
WDR76 WD repeat domain 76
ZNF41 zinc finger protein 41
ZNF493 zinc finger protein 493
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACTL8 actin-like 8
ANKRD36 ankyrin repeat domain 36
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX2 armadillo repeat containing, X-linked 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
C2ORF27A chromosome 2 open reading frame 27A
C5AR2 complement component 5a receptor 2
CAPN15 calpain 15
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKN2AIP CDKN2A interacting protein
CPTP ceramide-1-phosphate transfer protein
CRY2 cryptochrome circadian clock 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
ENO3 enolase 3 (beta, muscle)
ERCC4 excision repair cross-complementation group 4
ETNK2 ethanolamine kinase 2
EXOC6B exocyst complex component 6B
FADS2 fatty acid desaturase 2
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FAM189A2 family with sequence similarity 189, member A2
FAM46C family with sequence similarity 46, member C
FLJ22184
GMIP GEM interacting protein
GMPR guanosine monophosphate reductase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2L G patch domain containing 2-like
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
HOXC5 homeobox C5
ICK intestinal cell (MAK-like) kinase
IQSEC2 IQ motif and Sec7 domain 2
ITPKB inositol-trisphosphate 3-kinase B
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KLHL26 kelch-like family member 26
LOC729164 hCG1732469
LRP3 low density lipoprotein receptor-related protein 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCMBP minichromosome maintenance complex binding protein
MSMB microseminoprotein, beta-
MTCP1 mature T-cell proliferation 1
MTRF1 mitochondrial translational release factor 1
MYOZ3 myozenin 3
NLRX1 NLR family member X1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB8 protocadherin beta 8
PDE12 phosphodiesterase 12
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G15 phospholipase A2, group XV
PLXNA3 plexin A3
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRR4 proline rich 4 (lacrimal)
RFTN1 raftlin, lipid raft linker 1
RPAP1 RNA polymerase II associated protein 1
S100A2 S100 calcium binding protein A2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPIDR scaffolding protein involved in DNA repair
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
TBC1D2 TBC1 domain family, member 2
THRB thyroid hormone receptor, beta
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3D tubulin, alpha 3d
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBQLN4 ubiquilin 4
USP6NL USP6 N-terminal like
WDR33 WD repeat domain 33
ZBTB48 zinc finger and BTB domain containing 48
ZNF329 zinc finger protein 329
ZNF358 zinc finger protein 358
ZNF768 zinc finger protein 768
Funding