piromidic acid-4575 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the piromidic acid-4575 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ARHGAP44 Rho GTPase activating protein 44
ARMC6 armadillo repeat containing 6
ARMCX4 armadillo repeat containing, X-linked 4
ARNT aryl hydrocarbon receptor nuclear translocator
ARR3 arrestin 3, retinal (X-arrestin)
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA1 carbonic anhydrase I
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CCDC85B coiled-coil domain containing 85B
CDK18 cyclin-dependent kinase 18
CGA glycoprotein hormones, alpha polypeptide
CLEC4E C-type lectin domain family 4, member E
CLTB clathrin, light chain B
CNTNAP2 contactin associated protein-like 2
COBL cordon-bleu WH2 repeat protein
COL14A1 collagen, type XIV, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CSNK1E casein kinase 1, epsilon
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DKFZP434C153 DKFZP434C153 protein
DMWD dystrophia myotonica, WD repeat containing
ERC2 ELKS/RAB6-interacting/CAST family member 2
FAM174B family with sequence similarity 174, member B
FAM69A family with sequence similarity 69, member A
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FUBP1 far upstream element (FUSE) binding protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPR135 G protein-coupled receptor 135
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ING2 inhibitor of growth family, member 2
IZUMO4 IZUMO family member 4
JAG1 jagged 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KIAA0040 KIAA0040
KIAA1456 KIAA1456
LARGE like-glycosyltransferase
LGALS8 lectin, galactoside-binding, soluble, 8
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MYT1 myelin transcription factor 1
NDE1 nudE neurodevelopment protein 1
NEBL nebulette
NEK3 NIMA-related kinase 3
NPR2 natriuretic peptide receptor 2
NSUN6 NOP2/Sun domain family, member 6
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSBP2 oxysterol binding protein 2
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PALM paralemmin
PAOX polyamine oxidase (exo-N4-amino)
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PEX16 peroxisomal biogenesis factor 16
PHF20 PHD finger protein 20
PITX1 paired-like homeodomain 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB4 proline-rich protein BstNI subfamily 4
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKG1 protein kinase, cGMP-dependent, type I
PSD4 pleckstrin and Sec7 domain containing 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REEP2 receptor accessory protein 2
RIN3 Ras and Rab interactor 3
RIOK3 RIO kinase 3
RPL13 ribosomal protein L13
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SOGA1 suppressor of glucose, autophagy associated 1
SPATA2L spermatogenesis associated 2-like
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STMN1 stathmin 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAGLN3 transgelin 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TMEM140 transmembrane protein 140
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
WDR1 WD repeat domain 1
WSB1 WD repeat and SOCS box containing 1
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACAD10 acyl-CoA dehydrogenase family, member 10
AGO4 argonaute RISC catalytic component 4
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALPK1 alpha-kinase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BNC1 basonuclin 1
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C4ORF29 chromosome 4 open reading frame 29
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CDON cell adhesion associated, oncogene regulated
CIDEB cell death-inducing DFFA-like effector b
CLCA1 chloride channel accessory 1
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
CSF1R colony stimulating factor 1 receptor
DSPP dentin sialophosphoprotein
DUSP8 dual specificity phosphatase 8
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
ERO1LB ERO1-like beta (S. cerevisiae)
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FAM131A family with sequence similarity 131, member A
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2BM histone cluster 1, H2bm
HIST1H4A histone cluster 1, H4a
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXC8 homeobox C8
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA0922 KIAA0922
LOC257152 uncharacterized LOC257152
LPAR6 lysophosphatidic acid receptor 6
LYRM9 LYR motif containing 9
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MEGF8 multiple EGF-like-domains 8
MFSD6 major facilitator superfamily domain containing 6
MMRN2 multimerin 2
MRPL44 mitochondrial ribosomal protein L44
MYO1F myosin IF
NDP Norrie disease (pseudoglioma)
NT5M 5',3'-nucleotidase, mitochondrial
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
PTPRS protein tyrosine phosphatase, receptor type, S
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB33B RAB33B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
SCAMP5 secretory carrier membrane protein 5
SCARA3 scavenger receptor class A, member 3
SETD8 SET domain containing (lysine methyltransferase) 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SYT17 synaptotagmin XVII
TBL3 transducin (beta)-like 3
TEAD3 TEA domain family member 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
VN1R1 vomeronasal 1 receptor 1
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF276 zinc finger protein 276
ZNF32 zinc finger protein 32
ZNF334 zinc finger protein 334
ZNF343 zinc finger protein 343
ZNF354A zinc finger protein 354A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZNF528 zinc finger protein 528