piroxicam-1405 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the piroxicam-1405 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALPK1 alpha-kinase 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ATG4B autophagy related 4B, cysteine peptidase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAG4 BCL2-associated athanogene 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C11ORF73 chromosome 11 open reading frame 73
C4BPA complement component 4 binding protein, alpha
CAMKV CaM kinase-like vesicle-associated
CAPN10 calpain 10
CC2D1A coiled-coil and C2 domain containing 1A
CD1D CD1d molecule
CD82 CD82 molecule
CEP170B centrosomal protein 170B
DAXX death-domain associated protein
DHFR dihydrofolate reductase
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
E2F4 E2F transcription factor 4, p107/p130-binding
ECT2 epithelial cell transforming 2
EIF4E eukaryotic translation initiation factor 4E
EML2 echinoderm microtubule associated protein like 2
EMX1 empty spiracles homeobox 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
FAM63A family with sequence similarity 63, member A
FAM89B family with sequence similarity 89, member B
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GJB1 gap junction protein, beta 1, 32kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNRH2 gonadotropin-releasing hormone 2
GSDMD gasdermin D
HBB hemoglobin, beta
HFE hemochromatosis
HOOK2 hook microtubule-tethering protein 2
IGLJ3 immunoglobulin lambda joining 3
IL27RA interleukin 27 receptor, alpha
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIN7C lin-7 homolog C (C. elegans)
LRRC37A2 leucine rich repeat containing 37, member A2
MAPK10 mitogen-activated protein kinase 10
MBIP MAP3K12 binding inhibitory protein 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NACA nascent polypeptide-associated complex alpha subunit
NET1 neuroepithelial cell transforming 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NPIPB15 nuclear pore complex interacting protein family, member B15
PARG poly (ADP-ribose) glycohydrolase
PDE8A phosphodiesterase 8A
PDE8B phosphodiesterase 8B
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PITPNA phosphatidylinositol transfer protein, alpha
PNISR PNN-interacting serine/arginine-rich protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRDM11 PR domain containing 11
PTK2 protein tyrosine kinase 2
RAB11B RAB11B, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RARB retinoic acid receptor, beta
RASAL1 RAS protein activator like 1 (GAP1 like)
RBMS1 RNA binding motif, single stranded interacting protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS9 ribosomal protein S9
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SAP18 Sin3A-associated protein, 18kDa
SGSM3 small G protein signaling modulator 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLITRK5 SLIT and NTRK-like family, member 5
SLMO2 slowmo homolog 2 (Drosophila)
SMO smoothened, frizzled class receptor
SNX19 sorting nexin 19
SRGN serglycin
TGFB3 transforming growth factor, beta 3
TLK2 tousled-like kinase 2
TM7SF2 transmembrane 7 superfamily member 2
TRIM14 tripartite motif containing 14
TRIM22 tripartite motif containing 22
TRIM3 tripartite motif containing 3
TXNL4A thioredoxin-like 4A
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WRN Werner syndrome, RecQ helicase-like
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF250 zinc finger protein 250
ZNF280D zinc finger protein 280D
ZNF468 zinc finger protein 468
ZNF609 zinc finger protein 609
ZNF623 zinc finger protein 623
ZNF721 zinc finger protein 721

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADM adrenomedullin
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ASB8 ankyrin repeat and SOCS box containing 8
ATAT1 alpha tubulin acetyltransferase 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
BEX1 brain expressed, X-linked 1
C11ORF68 chromosome 11 open reading frame 68
C3 complement component 3
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC94 coiled-coil domain containing 94
CDK6 cyclin-dependent kinase 6
CENPT centromere protein T
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHPT1 choline phosphotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDND1 claudin domain containing 1
CLK3 CDC-like kinase 3
COG7 component of oligomeric golgi complex 7
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DUSP5 dual specificity phosphatase 5
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERF Ets2 repressor factor
FAM46A family with sequence similarity 46, member A
FAM60A family with sequence similarity 60, member A
FANCF Fanconi anemia, complementation group F
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMEB1 glucocorticoid modulatory element binding protein 1
HSPB1 heat shock 27kDa protein 1
HTT huntingtin
IFITM3 interferon induced transmembrane protein 3
ILK integrin-linked kinase
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIFC1 kinesin family member C1
LAMP5 lysosomal-associated membrane protein family, member 5
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MNS1 meiosis-specific nuclear structural 1
MON1B MON1 secretory trafficking family member B
MRPL33 mitochondrial ribosomal protein L33
MSL1 male-specific lethal 1 homolog (Drosophila)
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NVL nuclear VCP-like
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK1IP1 PAK1 interacting protein 1
PBX3 pre-B-cell leukemia homeobox 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEF1 penta-EF-hand domain containing 1
PEX12 peroxisomal biogenesis factor 12
PGLYRP4 peptidoglycan recognition protein 4
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBM28 RNA binding motif protein 28
RNF111 ring finger protein 111
RPL39L ribosomal protein L39-like
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SEC24C SEC24 family member C
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMAD7 SMAD family member 7
SUN2 Sad1 and UNC84 domain containing 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D2B TBC1 domain family, member 2B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFB2M transcription factor B2, mitochondrial
TM9SF2 transmembrane 9 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM104 transmembrane protein 104
TMEM127 transmembrane protein 127
TRAPPC12 trafficking protein particle complex 12
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBAC1 UBA domain containing 1
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC24 zinc finger, CCHC domain containing 24
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF432 zinc finger protein 432
ZNF606 zinc finger protein 606
ZNHIT2 zinc finger, HIT-type containing 2