piroxicam-2089 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the piroxicam-2089 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
ATP13A3 ATPase type 13A3
ATXN7L3B ataxin 7-like 3B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C16ORF59 chromosome 16 open reading frame 59
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDK9 cyclin-dependent kinase 9
CFHR4 complement factor H-related 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CXCL5 chemokine (C-X-C motif) ligand 5
CYLD cylindromatosis (turban tumor syndrome)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DAPK3 death-associated protein kinase 3
DCAF13 DDB1 and CUL4 associated factor 13
DCAF4 DDB1 and CUL4 associated factor 4
DEPTOR DEP domain containing MTOR-interacting protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAL4 dynein, axonemal, light chain 4
EMP1 epithelial membrane protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK glycerol kinase
GSTA1 glutathione S-transferase alpha 1
HIPK3 homeodomain interacting protein kinase 3
HOOK1 hook microtubule-tethering protein 1
HPCAL4 hippocalcin like 4
HSF2 heat shock transcription factor 2
IL15 interleukin 15
IL6ST interleukin 6 signal transducer
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KDM8 lysine (K)-specific demethylase 8
KIRREL kin of IRRE like (Drosophila)
KLK10 kallikrein-related peptidase 10
LDB1 LIM domain binding 1
LPAR3 lysophosphatidic acid receptor 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEF2A myocyte enhancer factor 2A
MFAP3L microfibrillar-associated protein 3-like
MFSD6 major facilitator superfamily domain containing 6
MIS18BP1 MIS18 binding protein 1
MMP9 matrix metallopeptidase 9
MXD4 MAX dimerization protein 4
MYLK myosin light chain kinase
MYO1F myosin IF
NEK1 NIMA-related kinase 1
NKX3-2 NK3 homeobox 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OASL 2'-5'-oligoadenylate synthetase-like
OPCML opioid binding protein/cell adhesion molecule-like
PARVA parvin, alpha
PDE5A phosphodiesterase 5A, cGMP-specific
PEG3 paternally expressed 3
PHF2 PHD finger protein 2
PHF3 PHD finger protein 3
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKP3 plakophilin 3
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
QKI QKI, KH domain containing, RNA binding
RAB28 RAB28, member RAS oncogene family
RARS arginyl-tRNA synthetase
REST RE1-silencing transcription factor
RPH3AL rabphilin 3A-like (without C2 domains)
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A11 S100 calcium binding protein A11
SDC3 syndecan 3
SDCCAG3 serologically defined colon cancer antigen 3
SIKE1 suppressor of IKBKE 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNPH syntaphilin
SPAST spastin
SPATA6 spermatogenesis associated 6
STRN3 striatin, calmodulin binding protein 3
STX16 syntaxin 16
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYCP2 synaptonemal complex protein 2
TAT tyrosine aminotransferase
TBCD tubulin folding cofactor D
TBX19 T-box 19
TLR2 toll-like receptor 2
TMPO thymopoietin
TRIM14 tripartite motif containing 14
TRIM23 tripartite motif containing 23
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WASF3 WAS protein family, member 3
WDR4 WD repeat domain 4
ZBTB20 zinc finger and BTB domain containing 20
ZBTB22 zinc finger and BTB domain containing 22
ZBTB43 zinc finger and BTB domain containing 43
ZNF232 zinc finger protein 232
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACKR3 atypical chemokine receptor 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
ATP13A2 ATPase type 13A2
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
C19ORF24 chromosome 19 open reading frame 24
C1ORF105 chromosome 1 open reading frame 105
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CNTNAP1 contactin associated protein 1
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DUSP8 dual specificity phosphatase 8
ETAA1 Ewing tumor-associated antigen 1
FA2H fatty acid 2-hydroxylase
FAM184A family with sequence similarity 184, member A
FAM53B family with sequence similarity 53, member B
FGGY FGGY carbohydrate kinase domain containing
FZD8 frizzled class receptor 8
GALK1 galactokinase 1
GCHFR GTP cyclohydrolase I feedback regulator
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMIP GEM interacting protein
HIRA histone cell cycle regulator
HOXC10 homeobox C10
HYAL2 hyaluronoglucosaminidase 2
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKC inositol-trisphosphate 3-kinase C
KDM4D lysine (K)-specific demethylase 4D
KLHL3 kelch-like family member 3
KRT4 keratin 4, type II
KRT8P12 keratin 8 pseudogene 12
MB myoglobin
MPI mannose phosphate isomerase
MRPS34 mitochondrial ribosomal protein S34
MTG1 mitochondrial ribosome-associated GTPase 1
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NOP2 NOP2 nucleolar protein
NPFFR1 neuropeptide FF receptor 1
NPR3 natriuretic peptide receptor 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP62CL nucleoporin 62kDa C-terminal like
OSMR oncostatin M receptor
PC pyruvate carboxylase
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POMT2 protein-O-mannosyltransferase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRICKLE3 prickle homolog 3 (Drosophila)
PTDSS2 phosphatidylserine synthase 2
PTGES2 prostaglandin E synthase 2
PTPRE protein tyrosine phosphatase, receptor type, E
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RECQL4 RecQ protein-like 4
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN1 Ras and Rab interactor 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
STAG3 stromal antigen 3
STARD13 StAR-related lipid transfer (START) domain containing 13
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESK1 testis-specific kinase 1
TOR4A torsin family 4, member A
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
TXLNG taxilin gamma
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT10B wingless-type MMTV integration site family, member 10B
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF215 zinc finger protein 215
ZNF32 zinc finger protein 32
ZNF408 zinc finger protein 408
ZNF85 zinc finger protein 85
ZNF862 zinc finger protein 862