piroxicam-2252 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the piroxicam-2252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACPP acid phosphatase, prostate
ADM2 adrenomedullin 2
AIM1L absent in melanoma 1-like
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGAP1 Rho GTPase activating protein 1
ASPN asporin
ATXN2L ataxin 2-like
BIRC3 baculoviral IAP repeat containing 3
BIRC7 baculoviral IAP repeat containing 7
C7ORF69 chromosome 7 open reading frame 69
C8B complement component 8, beta polypeptide
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC64 coiled-coil domain containing 64
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTIF CBP80/20-dependent translation initiation factor
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCBLD2 discoidin, CUB and LCCL domain containing 2
DLX2 distal-less homeobox 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPB41 erythrocyte membrane protein band 4.1
EPHB1 EPH receptor B1
ESR1 estrogen receptor 1
FANCA Fanconi anemia, complementation group A
FGF1 fibroblast growth factor 1 (acidic)
FGFR3 fibroblast growth factor receptor 3
FNDC3A fibronectin type III domain containing 3A
FSHB follicle stimulating hormone, beta polypeptide
GPATCH4 G patch domain containing 4
GRM8 glutamate receptor, metabotropic 8
HNF4A hepatocyte nuclear factor 4, alpha
HOXB6 homeobox B6
IFIH1 interferon induced with helicase C domain 1
ITGB6 integrin, beta 6
KIF25-AS1 KIF25 antisense RNA 1
KRT15 keratin 15, type I
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MFGE8 milk fat globule-EGF factor 8 protein
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MID1 midline 1
MLANA melan-A
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTSS1L metastasis suppressor 1-like
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
MYLK myosin light chain kinase
NOD2 nucleotide-binding oligomerization domain containing 2
NRL neural retina leucine zipper
PAX2 paired box 2
PCDHB12 protocadherin beta 12
PDE10A phosphodiesterase 10A
PDGFD platelet derived growth factor D
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHTF2 putative homeodomain transcription factor 2
PKP2 plakophilin 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PODNL1 podocan-like 1
POU1F1 POU class 1 homeobox 1
PRKD1 protein kinase D1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PYY peptide YY
RAB40AL RAB40A, member RAS oncogene family-like
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS12 regulator of G-protein signaling 12
RUNX1 runt-related transcription factor 1
SMAD6 SMAD family member 6
SMCP sperm mitochondria-associated cysteine-rich protein
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAP23 synaptosomal-associated protein, 23kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPDEF SAM pointed domain containing ETS transcription factor
SPON1 spondin 1, extracellular matrix protein
SPTB spectrin, beta, erythrocytic
TJAP1 tight junction associated protein 1 (peripheral)
TMEM63A transmembrane protein 63A
TMOD1 tropomodulin 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TPP1 tripeptidyl peptidase I
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UBE4B ubiquitination factor E4B
UTS2 urotensin 2
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP64 ZFP64 zinc finger protein
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADCY7 adenylate cyclase 7
ADM adrenomedullin
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CD83 CD83 molecule
CES3 carboxylesterase 3
CNTN1 contactin 1
CXORF56 chromosome X open reading frame 56
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGAT1 diacylglycerol O-acyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC6B exocyst complex component 6B
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL2 F-box and leucine-rich repeat protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11710 uncharacterized protein FLJ11710
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFI1 growth factor independent 1 transcription repressor
GPATCH3 G patch domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H4A histone cluster 1, H4a
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
JMJD4 jumonji domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KREMEN2 kringle containing transmembrane protein 2
LAX1 lymphocyte transmembrane adaptor 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYPD3 LY6/PLAUR domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL52 mitochondrial ribosomal protein L52
MTCP1 mature T-cell proliferation 1
MYO1F myosin IF
N4BP3 NEDD4 binding protein 3
NIPAL2 NIPA-like domain containing 2
OLFML3 olfactomedin-like 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PER3 period circadian clock 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYHIN1 pyrin and HIN domain family, member 1
RASL11B RAS-like, family 11, member B
RFPL1S RFPL1 antisense RNA 1
RPL10L ribosomal protein L10-like
SECTM1 secreted and transmembrane 1
SKI SKI proto-oncogene
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SPTBN2 spectrin, beta, non-erythrocytic 2
STMN3 stathmin-like 3
STON1 stonin 1
TAOK1 TAO kinase 1
TBKBP1 TBK1 binding protein 1
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TNS2 tensin 2
TRIM36 tripartite motif containing 36
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSGA10 testis specific, 10
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324
ZNF623 zinc finger protein 623
ZNF76 zinc finger protein 76