piroxicam-7445 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the piroxicam-7445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A2M alpha-2-macroglobulin
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRA2 adhesion G protein-coupled receptor A2
ADORA1 adenosine A1 receptor
ADRBK2 adrenergic, beta, receptor kinase 2
AGMAT agmatine ureohydrolase (agmatinase)
AGPS alkylglycerone phosphate synthase
AK2 adenylate kinase 2
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APOE apolipoprotein E
APOM apolipoprotein M
AQP3 aquaporin 3 (Gill blood group)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARTN artemin
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BFSP1 beaded filament structural protein 1, filensin
C1ORF61 chromosome 1 open reading frame 61
CA9 carbonic anhydrase IX
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CD1C CD1c molecule
CD83 CD83 molecule
CEP162 centrosomal protein 162kDa
DVL3 dishevelled segment polarity protein 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDA ectodysplasin A
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM214B family with sequence similarity 214, member B
FAM63B family with sequence similarity 63, member B
FLJ11292
FLJ42627 uncharacterized LOC645644
FURIN furin (paired basic amino acid cleaving enzyme)
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-C major histocompatibility complex, class I, C
HYI hydroxypyruvate isomerase (putative)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL22 interleukin 22
IQCG IQ motif containing G
IQCK IQ motif containing K
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0930 KIAA0930
KLF2 Kruppel-like factor 2
LAPTM5 lysosomal protein transmembrane 5
LIMK1 LIM domain kinase 1
LOC390998 ribosomal protein L10 pseudogene
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP2K5 mitogen-activated protein kinase kinase 5
MERTK MER proto-oncogene, tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MXD3 MAX dimerization protein 3
NAAA N-acylethanolamine acid amidase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NOX1 NADPH oxidase 1
NXPH4 neurexophilin 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAQR6 progestin and adipoQ receptor family member VI
PCDHB13 protocadherin beta 13
PDE4DIP phosphodiesterase 4D interacting protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POLM polymerase (DNA directed), mu
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB27B RAB27B, member RAS oncogene family
RANBP1 RAN binding protein 1
RARA retinoic acid receptor, alpha
RGS12 regulator of G-protein signaling 12
RND2 Rho family GTPase 2
RPL35A ribosomal protein L35a
RTEL1 regulator of telomere elongation helicase 1
SCAPER S-phase cyclin A-associated protein in the ER
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPN sialophorin
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SYNGR1 synaptogyrin 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAZ tafazzin
TBX19 T-box 19
TEX40 testis expressed 40
TK1 thymidine kinase 1, soluble
TMPRSS2 transmembrane protease, serine 2
TP53I11 tumor protein p53 inducible protein 11
TTLL3 tubulin tyrosine ligase-like family member 3
TUBA4B tubulin, alpha 4b
USP19 ubiquitin specific peptidase 19
USP34 ubiquitin specific peptidase 34
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIPR1 vasoactive intestinal peptide receptor 1
ZC3H7B zinc finger CCCH-type containing 7B
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZFAND5 zinc finger, AN1-type domain 5
ZNF134 zinc finger protein 134

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
AHDC1 AT hook, DNA binding motif, containing 1
ANXA1 annexin A1
ARHGAP11A Rho GTPase activating protein 11A
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
AXIN1 axin 1
C14ORF132 chromosome 14 open reading frame 132
C16ORF59 chromosome 16 open reading frame 59
C7ORF43 chromosome 7 open reading frame 43
CBX8 chromobox homolog 8
CCNO cyclin O
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
COPS7B COP9 signalosome subunit 7B
CTNNBL1 catenin, beta like 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DCP1A decapping mRNA 1A
DCTN4 dynactin 4 (p62)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ECSIT ECSIT signalling integrator
ELMO3 engulfment and cell motility 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
ERO1L ERO1-like (S. cerevisiae)
FA2H fatty acid 2-hydroxylase
FAM184A family with sequence similarity 184, member A
FNTB farnesyltransferase, CAAX box, beta
FSD1 fibronectin type III and SPRY domain containing 1
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR27 G protein-coupled receptor 27
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC11 histone deacetylase 11
HDAC4 histone deacetylase 4
HIST1H3G histone cluster 1, H3g
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
HP1BP3 heterochromatin protein 1, binding protein 3
IL15RA interleukin 15 receptor, alpha
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KLHL21 kelch-like family member 21
KRBOX4 KRAB box domain containing 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC20 leucine rich repeat containing 20
MTRF1 mitochondrial translational release factor 1
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NT5DC3 5'-nucleotidase domain containing 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX26 peroxisomal biogenesis factor 26
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRU protein tyrosine phosphatase, receptor type, U
PYCR1 pyrroline-5-carboxylate reductase 1
RAB4B RAB4B, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RFTN1 raftlin, lipid raft linker 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP2 RNA polymerase II associated protein 2
SERTAD3 SERTA domain containing 3
SIDT1 SID1 transmembrane family, member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3 stromal antigen 3
STBD1 starch binding domain 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TESK2 testis-specific kinase 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TPST2 tyrosylprotein sulfotransferase 2
TTC17 tetratricopeptide repeat domain 17
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H12A zinc finger CCCH-type containing 12A
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF248 zinc finger protein 248
ZNF254 zinc finger protein 254
ZNF324 zinc finger protein 324
ZNF557 zinc finger protein 557
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZSCAN26 zinc finger and SCAN domain containing 26