pivampicillin-3506 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pivampicillin-3506 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRA1A adrenoceptor alpha 1A
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP35 Rho GTPase activating protein 35
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARNT aryl hydrocarbon receptor nuclear translocator
ASIC2 acid sensing (proton gated) ion channel 2
ASIC4 acid sensing (proton gated) ion channel family member 4
BMP1 bone morphogenetic protein 1
BMP10 bone morphogenetic protein 10
C8ORF44 chromosome 8 open reading frame 44
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CDC14A cell division cycle 14A
CDYL chromodomain protein, Y-like
COL16A1 collagen, type XVI, alpha 1
CSF1R colony stimulating factor 1 receptor
CT55 cancer/testis antigen 55
CTSS cathepsin S
CXORF21 chromosome X open reading frame 21
DAAM2 dishevelled associated activator of morphogenesis 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK4 docking protein 4
ELMO1 engulfment and cell motility 1
FAM174B family with sequence similarity 174, member B
FAM184A family with sequence similarity 184, member A
FAM65B family with sequence similarity 65, member B
FGF18 fibroblast growth factor 18
FGF7 fibroblast growth factor 7
FHL1 four and a half LIM domains 1
FKBP10 FK506 binding protein 10, 65 kDa
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GK glycerol kinase
GK2 glycerol kinase 2
GP6 glycoprotein VI (platelet)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPSM3 G-protein signaling modulator 3
GZMK granzyme K (granzyme 3; tryptase II)
HDAC5 histone deacetylase 5
HEG1 heart development protein with EGF-like domains 1
HIPK3 homeodomain interacting protein kinase 3
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA10 homeobox A10
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KAZN kazrin, periplakin interacting protein
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRT6B keratin 6B, type II
LRRC8B leucine rich repeat containing 8 family, member B
MALT1 MALT1 paracaspase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAP1L1 nucleosome assembly protein 1-like 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NEB nebulin
NF2 neurofibromin 2 (merlin)
NPC1 Niemann-Pick disease, type C1
NT5E 5'-nucleotidase, ecto (CD73)
OSGIN1 oxidative stress induced growth inhibitor 1
PAPOLA poly(A) polymerase alpha
PARVA parvin, alpha
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNXL2 pecanex-like 2 (Drosophila)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLAUR plasminogen activator, urokinase receptor
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRMT2IP PRMT2 interacting protein
PRR4 proline rich 4 (lacrimal)
PTCH1 patched 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RPL35A ribosomal protein L35a
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIRT4 sirtuin 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNTG1 syntrophin, gamma 1
ST20 suppressor of tumorigenicity 20
TGM2 transglutaminase 2
TLDC1 TBC/LysM-associated domain containing 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM36 tripartite motif containing 36
TROVE2 TROVE domain family, member 2
TYRP1 tyrosinase-related protein 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZCCHC24 zinc finger, CCHC domain containing 24
ZFAND5 zinc finger, AN1-type domain 5
ZNF112 zinc finger protein 112
ZNF204P zinc finger protein 204, pseudogene
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADCY6 adenylate cyclase 6
AES amino-terminal enhancer of split
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALPK1 alpha-kinase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
C10ORF95 chromosome 10 open reading frame 95
C19ORF73 chromosome 19 open reading frame 73
CA11 carbonic anhydrase XI
CEP85 centrosomal protein 85kDa
CGA glycoprotein hormones, alpha polypeptide
CHPF chondroitin polymerizing factor
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPTP ceramide-1-phosphate transfer protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUEDC1 CUE domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
EMID1 EMI domain containing 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
EXD3 exonuclease 3'-5' domain containing 3
FAM46C family with sequence similarity 46, member C
FGF23 fibroblast growth factor 23
FKBP8 FK506 binding protein 8, 38kDa
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
GALE UDP-galactose-4-epimerase
GCHFR GTP cyclohydrolase I feedback regulator
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRTP1 growth hormone regulated TBC protein 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HOXC10 homeobox C10
INCENP inner centromere protein antigens 135/155kDa
INPP5J inositol polyphosphate-5-phosphatase J
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
KRT8P12 keratin 8 pseudogene 12
LAMB2 laminin, beta 2 (laminin S)
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN3 mucolipin 3
MED24 mediator complex subunit 24
MFAP2 microfibrillar-associated protein 2
MRPS18C mitochondrial ribosomal protein S18C
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPTX1 neuronal pentraxin I
NRGN neurogranin (protein kinase C substrate, RC3)
NT5C 5', 3'-nucleotidase, cytosolic
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARD6A par-6 family cell polarity regulator alpha
PARPBP PARP1 binding protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PLD2 phospholipase D2
PLXNA3 plexin A3
PPT2 palmitoyl-protein thioesterase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RASA2 RAS p21 protein activator 2
RASL11B RAS-like, family 11, member B
RFTN1 raftlin, lipid raft linker 1
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
S100A6 S100 calcium binding protein A6
SCRN3 secernin 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC41A3 solute carrier family 41, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SP1 Sp1 transcription factor
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STON1 stonin 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TESC tescalcin
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM115 transmembrane protein 115
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701