pivampicillin-5465 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pivampicillin-5465 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACBD4 acyl-CoA binding domain containing 4
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRL1 adhesion G protein-coupled receptor L1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF95 chromosome 10 open reading frame 95
C17ORF59 chromosome 17 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
CCDC132 coiled-coil domain containing 132
CCDC71 coiled-coil domain containing 71
CCKAR cholecystokinin A receptor
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8B CD8b molecule
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLSTN2 calsyntenin 2
CNGB3 cyclic nucleotide gated channel beta 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNS cystinosin, lysosomal cystine transporter
CXXC4 CXXC finger protein 4
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DES desmin
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EGR1 early growth response 1
EGR4 early growth response 4
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELL2 elongation factor, RNA polymerase II, 2
ELMO2 engulfment and cell motility 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERP44 endoplasmic reticulum protein 44
EVI5 ecotropic viral integration site 5
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLOT1 flotillin 1
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GRK5 G protein-coupled receptor kinase 5
GSAP gamma-secretase activating protein
HAP1 huntingtin-associated protein 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL4R interleukin 4 receptor
IL6ST interleukin 6 signal transducer
ING2 inhibitor of growth family, member 2
ITGA8 integrin, alpha 8
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIF25 kinesin family member 25
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP6 low density lipoprotein receptor-related protein 6
MAPK14 mitogen-activated protein kinase 14
MARK4 MAP/microtubule affinity-regulating kinase 4
MEG3 maternally expressed 3 (non-protein coding)
MST1 macrophage stimulating 1
MYH14 myosin, heavy chain 14, non-muscle
NOX1 NADPH oxidase 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARVA parvin, alpha
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PICALM phosphatidylinositol binding clathrin assembly protein
PLA2G10 phospholipase A2, group X
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PVT1 Pvt1 oncogene (non-protein coding)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RND2 Rho family GTPase 2
RTEL1 regulator of telomere elongation helicase 1
RUNDC3B RUN domain containing 3B
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SENP5 SUMO1/sentrin specific peptidase 5
SNAP23 synaptosomal-associated protein, 23kDa
SRSF5 serine/arginine-rich splicing factor 5
STX3 syntaxin 3
TAZ tafazzin
TBCD tubulin folding cofactor D
TFPI2 tissue factor pathway inhibitor 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPMT thiopurine S-methyltransferase
TRIM23 tripartite motif containing 23
TSPAN9 tetraspanin 9
VAC14 Vac14 homolog (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZFP69B ZFP69 zinc finger protein B
ZIC3 Zic family member 3
ZNF16 zinc finger protein 16
ZNF230 zinc finger protein 230
ZNF384 zinc finger protein 384
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
ATP13A2 ATPase type 13A2
ATXN2 ataxin 2
BACE1 beta-site APP-cleaving enzyme 1
C17ORF70 chromosome 17 open reading frame 70
C2ORF44 chromosome 2 open reading frame 44
C5 complement component 5
C9ORF9 chromosome 9 open reading frame 9
CAPRIN2 caprin family member 2
CDK20 cyclin-dependent kinase 20
CIDEC cell death-inducing DFFA-like effector c
CLCN5 chloride channel, voltage-sensitive 5
CLDN4 claudin 4
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYBG3 beta-gamma crystallin domain containing 3
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DUSP5 dual specificity phosphatase 5
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EPHA4 EPH receptor A4
FAM110B family with sequence similarity 110, member B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAS8 growth arrest-specific 8
GLB1L2 galactosidase, beta 1-like 2
GPR19 G protein-coupled receptor 19
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H1B histone cluster 1, H1b
HPN hepsin
IL17RA interleukin 17 receptor A
IL2 interleukin 2
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIZ kizuna centrosomal protein
KLF7 Kruppel-like factor 7 (ubiquitous)
KREMEN2 kringle containing transmembrane protein 2
KRT24 keratin 24, type I
LAMB2 laminin, beta 2 (laminin S)
LOC390998 ribosomal protein L10 pseudogene
LOC642236 FSHD region gene 1 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MITF microphthalmia-associated transcription factor
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL5 myosin, light chain 5, regulatory
MYO9A myosin IXA
NHEJ1 nonhomologous end-joining factor 1
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NR1H2 nuclear receptor subfamily 1, group H, member 2
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDE12 phosphodiesterase 12
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLSCR4 phospholipid scramblase 4
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLL polymerase (DNA directed), lambda
PRF1 perforin 1 (pore forming protein)
PRODH proline dehydrogenase (oxidase) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB36 RAB36, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUFY2 RUN and FYVE domain containing 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETD8 SET domain containing (lysine methyltransferase) 8
SETMAR SET domain and mariner transposase fusion gene
SHARPIN SHANK-associated RH domain interactor
SLC12A9 solute carrier family 12, member 9
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SREK1IP1 SREK1-interacting protein 1
STK16 serine/threonine kinase 16
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM104 transmembrane protein 104
TMEM183A transmembrane protein 183A
TRABD TraB domain containing
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WWC2 WW and C2 domain containing 2
XYLT2 xylosyltransferase II
ZNF41 zinc finger protein 41
ZNF442 zinc finger protein 442
ZNF701 zinc finger protein 701
ZSCAN16 zinc finger and SCAN domain containing 16