pivmecillinam-2973 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pivmecillinam-2973 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADGRB1 adhesion G protein-coupled receptor B1
AIF1 allograft inflammatory factor 1
APLP2 amyloid beta (A4) precursor-like protein 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARSB arylsulfatase B
ATG10 autophagy related 10
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C11ORF16 chromosome 11 open reading frame 16
C16ORF58 chromosome 16 open reading frame 58
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CDC25C cell division cycle 25C
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNOT2 CCR4-NOT transcription complex, subunit 2
CORT cortistatin
CRAT carnitine O-acetyltransferase
CT62 cancer/testis antigen 62
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKG diacylglycerol kinase, gamma 90kDa
EPHB6 EPH receptor B6
ESRRA estrogen-related receptor alpha
FLJ11292
FLRT1 fibronectin leucine rich transmembrane protein 1
FMO6P flavin containing monooxygenase 6 pseudogene
FRS2 fibroblast growth factor receptor substrate 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIPC1 GIPC PDZ domain containing family, member 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HIST1H3G histone cluster 1, H3g
ICOSLG inducible T-cell co-stimulator ligand
IFT38 intraflagellar transport 38
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
INO80B INO80 complex subunit B
IQSEC2 IQ motif and Sec7 domain 2
KIF17 kinesin family member 17
KLHL22 kelch-like family member 22
KLHL28 kelch-like family member 28
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP25 matrix metallopeptidase 25
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MYOZ3 myozenin 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLFML2A olfactomedin-like 2A
OSGIN2 oxidative stress induced growth inhibitor family member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLS3 plastin 3
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRB1 proline-rich protein BstNI subfamily 1
PRKCQ protein kinase C, theta
PTAFR platelet-activating factor receptor
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYGB phosphorylase, glycogen; brain
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RELN reelin
RHOD ras homolog family member D
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
SETD2 SET domain containing 2
SETD8 SET domain containing (lysine methyltransferase) 8
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLAMF8 SLAM family member 8
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOGA1 suppressor of glucose, autophagy associated 1
SPAG8 sperm associated antigen 8
SPRR1A small proline-rich protein 1A
SRPK2 SRSF protein kinase 2
STK38 serine/threonine kinase 38
STXBP6 syntaxin binding protein 6 (amisyn)
SYMPK symplekin
TAPT1 transmembrane anterior posterior transformation 1
THBS1 thrombospondin 1
TRIM15 tripartite motif containing 15
TTLL5 tubulin tyrosine ligase-like family member 5
UCN urocortin
UMPS uridine monophosphate synthetase
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDR25 WD repeat domain 25
WFDC2 WAP four-disulfide core domain 2
ZBTB7A zinc finger and BTB domain containing 7A
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF276 zinc finger protein 276
ZNF34 zinc finger protein 34
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACPP acid phosphatase, prostate
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
BHLHE41 basic helix-loop-helix family, member e41
BLVRB biliverdin reductase B
C1ORF21 chromosome 1 open reading frame 21
C22ORF46 chromosome 22 open reading frame 46
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC88C coiled-coil domain containing 88C
CD69 CD69 molecule
CD9 CD9 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CISH cytokine inducible SH2-containing protein
COL15A1 collagen, type XV, alpha 1
CXORF56 chromosome X open reading frame 56
DGAT1 diacylglycerol O-acyltransferase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK2 dickkopf WNT signaling pathway inhibitor 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM184A family with sequence similarity 184, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGL2 fibrinogen-like 2
FHL3 four and a half LIM domains 3
FKBP9 FK506 binding protein 9, 63 kDa
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GEM GTP binding protein overexpressed in skeletal muscle
GID4 GID complex subunit 4
GJA1 gap junction protein, alpha 1, 43kDa
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST3H2A histone cluster 3, H2a
HP haptoglobin
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
IFNA14 interferon, alpha 14
IL24 interleukin 24
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRX5 iroquois homeobox 5
KIAA0319L KIAA0319-like
KIF13B kinesin family member 13B
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LNPEP leucyl/cystinyl aminopeptidase
LPAR6 lysophosphatidic acid receptor 6
MAGED1 melanoma antigen family D1
MANSC1 MANSC domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MST1 macrophage stimulating 1
MVD mevalonate (diphospho) decarboxylase
MX1 MX dynamin-like GTPase 1
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5M 5',3'-nucleotidase, mitochondrial
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PGM1 phosphoglucomutase 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
POMZP3 POM121 and ZP3 fusion
POR P450 (cytochrome) oxidoreductase
RETN resistin
RGS13 regulator of G-protein signaling 13
RIN1 Ras and Rab interactor 1
SFXN1 sideroflexin 1
SIL1 SIL1 nucleotide exchange factor
SLC12A9 solute carrier family 12, member 9
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPP1 secreted phosphoprotein 1
SSFA2 sperm specific antigen 2
THRAP3 thyroid hormone receptor associated protein 3
TLR6 toll-like receptor 6
TMEM140 transmembrane protein 140
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM39B transmembrane protein 39B
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TRIM25 tripartite motif containing 25
TRIM36 tripartite motif containing 36
TSPYL2 TSPY-like 2
TUBA3D tubulin, alpha 3d
ULK1 unc-51 like autophagy activating kinase 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB6 zinc finger and BTB domain containing 6
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF254 zinc finger protein 254
ZNF468 zinc finger protein 468
ZNF76 zinc finger protein 76