| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the pivmecillinam-3535 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF6B | activating transcription factor 6 beta |
| B9D1 | B9 protein domain 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CALML5 | calmodulin-like 5 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCDC85B | coiled-coil domain containing 85B |
| CD58 | CD58 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLDN6 | claudin 6 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTBP2 | C-terminal binding protein 2 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DOPEY2 | dopey family member 2 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FOSL2 | FOS-like antigen 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GFI1 | growth factor independent 1 transcription repressor |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR143 | G protein-coupled receptor 143 |
| HDAC11 | histone deacetylase 11 |
| HDAC5 | histone deacetylase 5 |
| HLA-G | major histocompatibility complex, class I, G |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGL | immunoglobulin lambda locus |
| KIF22 | kinesin family member 22 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRT85 | keratin 85, type II |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMTK1 | lemur tail kinase 1 |
| MARS | methionyl-tRNA synthetase |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP3 | matrix metallopeptidase 3 |
| NEB | nebulin |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NPAS2 | neuronal PAS domain protein 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PER1 | period circadian clock 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLLP | plasmolipin |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PSEN1 | presenilin 1 |
| PXN | paxillin |
| RAB30 | RAB30, member RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RHOT2 | ras homolog family member T2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A11 | S100 calcium binding protein A11 |
| S100A6 | S100 calcium binding protein A6 |
| S100A8 | S100 calcium binding protein A8 |
| SAFB2 | scaffold attachment factor B2 |
| SIX1 | SIX homeobox 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMTN | smoothelin |
| SNX13 | sorting nexin 13 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STEAP4 | STEAP family member 4 |
| STRA6 | stimulated by retinoic acid 6 |
| SYNJ1 | synaptojanin 1 |
| TEP1 | telomerase-associated protein 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM209 | transmembrane protein 209 |
| TMEM212 | transmembrane protein 212 |
| TMEM254 | transmembrane protein 254 |
| TMEM8B | transmembrane protein 8B |
| TREX1 | three prime repair exonuclease 1 |
| WWOX | WW domain containing oxidoreductase |
| YTHDC2 | YTH domain containing 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD17B | abhydrolase domain containing 17B |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCNO | cyclin O |
| CDK3 | cyclin-dependent kinase 3 |
| CENPO | centromere protein O |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORT | cortistatin |
| CTAGE9 | CTAGE family, member 9 |
| EFNA3 | ephrin-A3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EN2 | engrailed homeobox 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM46C | family with sequence similarity 46, member C |
| FLNC | filamin C, gamma |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FRMD1 | FERM domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GLRA1 | glycine receptor, alpha 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR157 | G protein-coupled receptor 157 |
| GPR87 | G protein-coupled receptor 87 |
| HDAC4 | histone deacetylase 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AK | histone cluster 1, H2ak |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF1 | interferon regulatory factor 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JMJD4 | jumonji domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINS | lines homolog (Drosophila) |
| LRRC20 | leucine rich repeat containing 20 |
| MAGEA6 | melanoma antigen family A6 |
| MEIS1 | Meis homeobox 1 |
| NES | nestin |
| NNAT | neuronatin |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OCLM | oculomedin |
| ONECUT2 | one cut homeobox 2 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHB13 | protocadherin beta 13 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRR14L | proline rich 14-like |
| PTK6 | protein tyrosine kinase 6 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF170 | ring finger protein 170 |
| RPGRIP1L | RPGRIP1-like |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TCP10 | t-complex 10 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM104 | transmembrane protein 104 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOM1 | target of myb1 (chicken) |
| TRAIP | TRAF interacting protein |
| TSGA10 | testis specific, 10 |
| TSPAN5 | tetraspanin 5 |
| TUBA3D | tubulin, alpha 3d |
| VLDLR | very low density lipoprotein receptor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF250 | zinc finger protein 250 |
| ZNF34 | zinc finger protein 34 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
