| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the pivmecillinam-6014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAMDEC1 | ADAM-like, decysin 1 |
| AK1 | adenylate kinase 1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALPI | alkaline phosphatase, intestinal |
| AQP3 | aquaporin 3 (Gill blood group) |
| AQP5 | aquaporin 5 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C3 | complement component 3 |
| C4BPA | complement component 4 binding protein, alpha |
| CA4 | carbonic anhydrase IV |
| CALCR | calcitonin receptor |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC81 | coiled-coil domain containing 81 |
| CD70 | CD70 molecule |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEL | carboxyl ester lipase |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CPA4 | carboxypeptidase A4 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CPQ | carboxypeptidase Q |
| CXORF21 | chromosome X open reading frame 21 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DTNA | dystrobrevin, alpha |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EXOSC1 | exosome component 1 |
| FAM186A | family with sequence similarity 186, member A |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FOXG1 | forkhead box G1 |
| GFER | growth factor, augmenter of liver regeneration |
| GPATCH4 | G patch domain containing 4 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| IBSP | integrin-binding sialoprotein |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| JRK | Jrk homolog (mouse) |
| KIAA1644 | KIAA1644 |
| KIF21B | kinesin family member 21B |
| LEPR | leptin receptor |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMF2 | lipase maturation factor 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MNDA | myeloid cell nuclear differentiation antigen |
| NF1 | neurofibromin 1 |
| NFIB | nuclear factor I/B |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PLCD1 | phospholipase C, delta 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRLR | prolactin receptor |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RASAL2 | RAS protein activator like 2 |
| RASL11B | RAS-like, family 11, member B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF122 | ring finger protein 122 |
| RPAIN | RPA interacting protein |
| S100A8 | S100 calcium binding protein A8 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPAG6 | sperm associated antigen 6 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TBR1 | T-box, brain, 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFF2 | trefoil factor 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFR2 | transferrin receptor 2 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TMEM63A | transmembrane protein 63A |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| VDAC3 | voltage-dependent anion channel 3 |
| YTHDC1 | YTH domain containing 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF391 | zinc finger protein 391 |
| ZNF442 | zinc finger protein 442 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD4 | abhydrolase domain containing 4 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| AXIN1 | axin 1 |
| B9D2 | B9 protein domain 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA11 | carbonic anhydrase XI |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC186 | coiled-coil domain containing 186 |
| CD82 | CD82 molecule |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CDON | cell adhesion associated, oncogene regulated |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CSF1R | colony stimulating factor 1 receptor |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAAH | fatty acid amide hydrolase |
| FPGS | folylpolyglutamate synthase |
| GSTT1 | glutathione S-transferase theta 1 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| IFT81 | intraflagellar transport 81 |
| JMJD4 | jumonji domain containing 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLF2 | Kruppel-like factor 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOSPD3 | motile sperm domain containing 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEUROD4 | neuronal differentiation 4 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGES2 | prostaglandin E synthase 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB30 | RAB30, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFXAP | regulatory factor X-associated protein |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF43 | ring finger protein 43 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SIK1 | salt-inducible kinase 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNX15 | sorting nexin 15 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPRR2B | small proline-rich protein 2B |
| SSBP3 | single stranded DNA binding protein 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCTN2 | tectonic family member 2 |
| TEP1 | telomerase-associated protein 1 |
| TH | tyrosine hydroxylase |
| TLN1 | talin 1 |
| TLR5 | toll-like receptor 5 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VASH1 | vasohibin 1 |
| VNN2 | vanin 2 |
| WDR4 | WD repeat domain 4 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF211 | zinc finger protein 211 |
| ZNF606 | zinc finger protein 606 |
| ZNF862 | zinc finger protein 862 |
