| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pizotifen-5072 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ASTN2 | astrotactin 2 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CCNO | cyclin O |
| CD4 | CD4 molecule |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFP | complement factor properdin |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN17 | claudin 17 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH1 | cytohesin 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GPM6B | glycoprotein M6B |
| HAMP | hepcidin antimicrobial peptide |
| HDAC9 | histone deacetylase 9 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| INHBA | inhibin, beta A |
| JAG1 | jagged 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| LCAT | lecithin-cholesterol acyltransferase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP13 | matrix metallopeptidase 13 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTSS1L | metastasis suppressor 1-like |
| NEK1 | NIMA-related kinase 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOTCH3 | notch 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRP2 | neuropilin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ONECUT2 | one cut homeobox 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| PTX3 | pentraxin 3, long |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SAA3P | serum amyloid A3 pseudogene |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMAD6 | SMAD family member 6 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STC2 | stanniocalcin 2 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYN2 | synapsin II |
| TGFB2 | transforming growth factor, beta 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF287 | zinc finger protein 287 |
| ZNF3 | zinc finger protein 3 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| AK5 | adenylate kinase 5 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA10 | annexin A10 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| AXIN1 | axin 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BEX1 | brain expressed, X-linked 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAPN15 | calpain 15 |
| CCDC25 | coiled-coil domain containing 25 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CHKB | choline kinase beta |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRYBA2 | crystallin, beta A2 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EN1 | engrailed homeobox 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| ETNK2 | ethanolamine kinase 2 |
| EXO1 | exonuclease 1 |
| FAM192A | family with sequence similarity 192, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXN2 | forkhead box N2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPX2 | glutathione peroxidase 2 |
| GRAMD1B | GRAM domain containing 1B |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0556 | KIAA0556 |
| KLHL3 | kelch-like family member 3 |
| LOC257152 | uncharacterized LOC257152 |
| LOC730101 | uncharacterized LOC730101 |
| MOB3B | MOB kinase activator 3B |
| MON1B | MON1 secretory trafficking family member B |
| NBEAL2 | neurobeachin-like 2 |
| NCS1 | neuronal calcium sensor 1 |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PALMD | palmdelphin |
| PARD6A | par-6 family cell polarity regulator alpha |
| PER3 | period circadian clock 3 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPL | periplakin |
| PRKCE | protein kinase C, epsilon |
| PRR4 | proline rich 4 (lacrimal) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPATA7 | spermatogenesis associated 7 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST20 | suppressor of tumorigenicity 20 |
| STIM1 | stromal interaction molecule 1 |
| SYTL2 | synaptotagmin-like 2 |
| TMEM132A | transmembrane protein 132A |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TUBA1A | tubulin, alpha 1a |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| XYLT2 | xylosyltransferase II |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF254 | zinc finger protein 254 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
