| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pizotifen-5491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANKRD55 | ankyrin repeat domain 55 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC93 | coiled-coil domain containing 93 |
| CDC25C | cell division cycle 25C |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COL6A1 | collagen, type VI, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| EGR1 | early growth response 1 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ELN | elastin |
| ETV5 | ets variant 5 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGL1 | fibrinogen-like 1 |
| FOXN2 | forkhead box N2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GPATCH4 | G patch domain containing 4 |
| HCG4B | HLA complex group 4B (non-protein coding) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INO80B | INO80 complex subunit B |
| ITK | IL2-inducible T-cell kinase |
| JUN | jun proto-oncogene |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLF2 | Kruppel-like factor 2 |
| LMTK1 | lemur tail kinase 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MTSS1 | metastasis suppressor 1 |
| MZF1 | myeloid zinc finger 1 |
| NCOA2 | nuclear receptor coactivator 2 |
| NECAP2 | NECAP endocytosis associated 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OGFR | opioid growth factor receptor |
| OPRL1 | opiate receptor-like 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLAU | plasminogen activator, urokinase |
| PLCG1 | phospholipase C, gamma 1 |
| PML | promyelocytic leukemia |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PYGB | phosphorylase, glycogen; brain |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAG1 | recombination activating gene 1 |
| RIMBP2 | RIMS binding protein 2 |
| RRBP1 | ribosome binding protein 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SLN | sarcolipin |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPEG | SPEG complex locus |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STX3 | syntaxin 3 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TCP10L | t-complex 10-like |
| TEX15 | testis expressed 15 |
| TEX40 | testis expressed 40 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM209 | transmembrane protein 209 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM10 | tripartite motif containing 10 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSPAN32 | tetraspanin 32 |
| USP2 | ubiquitin specific peptidase 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZNF174 | zinc finger protein 174 |
| ZNF230 | zinc finger protein 230 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AFF4 | AF4/FMR2 family, member 4 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARHGAP19 | Rho GTPase activating protein 19 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATG9A | autophagy related 9A |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BBC3 | BCL2 binding component 3 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CCDC51 | coiled-coil domain containing 51 |
| CCNL2 | cyclin L2 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP170B | centrosomal protein 170B |
| CHKB | choline kinase beta |
| COQ6 | coenzyme Q6 monooxygenase |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CXORF56 | chromosome X open reading frame 56 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FADS3 | fatty acid desaturase 3 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FILIP1L | filamin A interacting protein 1-like |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAB2 | GRB2-associated binding protein 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INO80D | INO80 complex subunit D |
| IRF2 | interferon regulatory factor 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC730101 | uncharacterized LOC730101 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MMP9 | matrix metallopeptidase 9 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| ONECUT2 | one cut homeobox 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PANK4 | pantothenate kinase 4 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARPBP | PARP1 binding protein |
| PCBP4 | poly(rC) binding protein 4 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PITX2 | paired-like homeodomain 2 |
| PKN1 | protein kinase N1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLIN3 | perilipin 3 |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKX | protein kinase, X-linked |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| RAB4B | RAB4B, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF2 | ring finger protein 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBCCD1 | TBCC domain containing 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMEM134 | transmembrane protein 134 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VGF | VGF nerve growth factor inducible |
| WDR91 | WD repeat domain 91 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF250 | zinc finger protein 250 |
| ZNF701 | zinc finger protein 701 |
