| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pizotifen-6513 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALOX12 | arachidonate 12-lipoxygenase |
| APOBR | apolipoprotein B receptor |
| ARTN | artemin |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF3 | activating transcription factor 3 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| B9D2 | B9 protein domain 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C2 | complement component 2 |
| CALCR | calcitonin receptor |
| CALD1 | caldesmon 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD6 | CD6 molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DESI2 | desumoylating isopeptidase 2 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DOCK9 | dedicator of cytokinesis 9 |
| DTNA | dystrobrevin, alpha |
| DUSP4 | dual specificity phosphatase 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ETV5 | ets variant 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GLUL | glutamate-ammonia ligase |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GNRHR | gonadotropin-releasing hormone receptor |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| HDAC5 | histone deacetylase 5 |
| HMOX1 | heme oxygenase 1 |
| HOMER3 | homer scaffolding protein 3 |
| IFFO1 | intermediate filament family orphan 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ING1 | inhibitor of growth family, member 1 |
| INSIG1 | insulin induced gene 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JPH3 | junctophilin 3 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KLF6 | Kruppel-like factor 6 |
| KLK2 | kallikrein-related peptidase 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MBD1 | methyl-CpG binding domain protein 1 |
| MCOLN1 | mucolipin 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MMP3 | matrix metallopeptidase 3 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NIPAL3 | NIPA-like domain containing 3 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE11A | phosphodiesterase 11A |
| PLSCR4 | phospholipid scramblase 4 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB6B | RAB6B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| S100A13 | S100 calcium binding protein A13 |
| S100A8 | S100 calcium binding protein A8 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC43A3 | solute carrier family 43, member 3 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SPAG11A | sperm associated antigen 11A |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STX5 | syntaxin 5 |
| STX7 | syntaxin 7 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TGM2 | transglutaminase 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TRIM2 | tripartite motif containing 2 |
| TRIM68 | tripartite motif containing 68 |
| TUBA3C | tubulin, alpha 3c |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF280A | zinc finger protein 280A |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ARMC6 | armadillo repeat containing 6 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCDC69 | coiled-coil domain containing 69 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDON | cell adhesion associated, oncogene regulated |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK1 | dedicator of cytokinesis 1 |
| DOCK4 | dedicator of cytokinesis 4 |
| DYSF | dysferlin |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENO3 | enolase 3 (beta, muscle) |
| FAAH | fatty acid amide hydrolase |
| FAM192A | family with sequence similarity 192, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXO46 | F-box protein 46 |
| FGF23 | fibroblast growth factor 23 |
| FILIP1L | filamin A interacting protein 1-like |
| FLT4 | fms-related tyrosine kinase 4 |
| GRPR | gastrin-releasing peptide receptor |
| GSTP1 | glutathione S-transferase pi 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4F | histone cluster 1, H4f |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0754 | KIAA0754 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC729164 | hCG1732469 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYRM9 | LYR motif containing 9 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTSS1L | metastasis suppressor 1-like |
| MYL5 | myosin, light chain 5, regulatory |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NEK11 | NIMA-related kinase 11 |
| NLRX1 | NLR family member X1 |
| NOL12 | nucleolar protein 12 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPH4 | neurexophilin 4 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| PDGFD | platelet derived growth factor D |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGBD5 | piggyBac transposable element derived 5 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TCHH | trichohyalin |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TFF2 | trefoil factor 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| TPCN1 | two pore segment channel 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN2 | tetraspanin 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VIM | vimentin |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF747 | zinc finger protein 747 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
