pkd2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description polycystic kidney disease 2 (autosomal dominant)|This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 5311)
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Genes

44 genes co-occuring with the biological term pkd2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ARF1 ADP-ribosylation factor 1
BICC1 BicC family RNA binding protein 1
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAMLG calcium modulating ligand
CCKBR cholecystokinin B receptor
CD274 CD274 molecule
CHGA chromogranin A
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CXCL8 chemokine (C-X-C motif) ligand 8
DIAPH1 diaphanous-related formin 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
HDAC1 histone deacetylase 1
HSPB1 heat shock 27kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL2 interleukin 2
KIDINS220 kinase D-interacting substrate, 220kDa
LCK LCK proto-oncogene, Src family tyrosine kinase
LUM lumican
MAPK14 mitogen-activated protein kinase 14
MIR17 microRNA 17
NCAM1 neural cell adhesion molecule 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRG1 neuregulin 1
NTS neurotensin
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFC platelet derived growth factor C
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKD2L1 polycystic kidney disease 2-like 1
PKD3 polycystic kidney disease 3 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLAU plasminogen activator, urokinase
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1