plague Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food. (Human Disease Ontology, DOID_3482)
Similar Terms
Downloads & Tools

Genes

177 genes co-occuring with the disease plague in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ARMC1 armadillo repeat containing 1 1.55956
CTSC cathepsin C 1.41271
CDH3 cadherin 3, type 1, P-cadherin (placental) 1.27126
TIGD1 tigger transposable element derived 1 1.21825
HMSD histocompatibility (minor) serpin domain containing 1.18798
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.18281
PTPRD protein tyrosine phosphatase, receptor type, D 1.17507
KAT2B K(lysine) acetyltransferase 2B 1.13543
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.08873
PLG plasminogen 1.07404
LY75 lymphocyte antigen 75 1.04882
MEST mesoderm specific transcript 1.03746
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.02988
ACOT8 acyl-CoA thioesterase 8 0.985164
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.964148
PARP10 poly (ADP-ribose) polymerase family, member 10 0.940364
GAP43 growth associated protein 43 0.915963
PTS 6-pyruvoyltetrahydropterin synthase 0.912668
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.911433
GALM galactose mutarotase (aldose 1-epimerase) 0.879014
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.849945
TLR4 toll-like receptor 4 0.834378
TNF tumor necrosis factor 0.833148
CARD17 caspase recruitment domain family, member 17 0.813462
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.813052
MTMR11 myotubularin related protein 11 0.787213
WARS tryptophanyl-tRNA synthetase 0.786803
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.783936
TLR2 toll-like receptor 2 0.778613
CD79A CD79a molecule, immunoglobulin-associated alpha 0.750457
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.747204
CRY2 cryptochrome circadian clock 2 0.711989
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.699919
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.689092
TKFC triokinase/FMN cyclase 0.687091
CD4 CD4 molecule 0.667152
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 0.663181
MGAM maltase-glucoamylase 0.653276
CRY1 cryptochrome circadian clock 1 0.652484
CLEC6A C-type lectin domain family 6, member A 0.649323
CLEC4A C-type lectin domain family 4, member A 0.633563
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.622575
RND1 Rho family GTPase 1 0.622183
AGPS alkylglycerone phosphate synthase 0.617094
PKP3 plakophilin 3 0.613183
SUMF2 sulfatase modifying factor 2 0.607714
RIMS1 regulating synaptic membrane exocytosis 1 0.557509
HMP19 HMP19 protein 0.554015
HCFC1 host cell factor C1 0.551686
MYLIP myosin regulatory light chain interacting protein 0.548971
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.543155
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.538506
TLR6 toll-like receptor 6 0.531541
CNOT1 CCR4-NOT transcription complex, subunit 1 0.531154
BRD3 bromodomain containing 3 0.529608
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.529222
TTK TTK protein kinase 0.51534
RBBP9 retinoblastoma binding protein 9 0.504207
VDAC2 voltage-dependent anion channel 2 0.496939
REEP5 receptor accessory protein 5 0.493885
NAGS N-acetylglutamate synthase 0.492359
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.487027
NCR3 natural cytotoxicity triggering receptor 3 0.485125
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.483604
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.47753
MYD88 myeloid differentiation primary response 88 0.476014
CSN1S1 casein alpha s1 0.47374
PGLYRP1 peptidoglycan recognition protein 1 0.451454
PKP1 plakophilin 1 0.430017
PRKCD protein kinase C, delta 0.429266
OCM2 oncomodulin 2 0.424014
DUSP3 dual specificity phosphatase 3 0.415398
SAMM50 SAMM50 sorting and assembly machinery component 0.412779
OCM oncomodulin 0.406051
ZFHX3 zinc finger homeobox 3 0.403064
DCSTAMP dendrocyte expressed seven transmembrane protein 0.397843
CCNE1 cyclin E1 0.396353
ACHE acetylcholinesterase (Yt blood group) 0.393746
A4GALT alpha 1,4-galactosyltransferase 0.390769
APOLD1 apolipoprotein L domain containing 1 0.390769
CELA3B chymotrypsin-like elastase family, member 3B 0.387051
METTL13 methyltransferase like 13 0.385193
TLR1 toll-like receptor 1 0.383708
TST thiosulfate sulfurtransferase (rhodanese) 0.378514
TDG thymine-DNA glycosylase 0.373698
SNRPA small nuclear ribonucleoprotein polypeptide A 0.372587
TLR10 toll-like receptor 10 0.370737
ABHD14A abhydrolase domain containing 14A 0.363716
LSR lipolysis stimulated lipoprotein receptor 0.357814
RETNLB resistin like beta 0.355972
UPK2 uroplakin 2 0.351555
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.347511
RGMB repulsive guidance molecule family member b 0.337975
PLCH2 phospholipase C, eta 2 0.3292
HTRA1 HtrA serine peptidase 1 0.3292
NLRP12 NLR family, pyrin domain containing 12 0.328469
IL10 interleukin 10 0.318272
REST RE1-silencing transcription factor 0.307395
ARHGAP1 Rho GTPase activating protein 1 0.305587
LCK LCK proto-oncogene, Src family tyrosine kinase 0.292616
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.286519
DUT deoxyuridine triphosphatase 0.283655
GH1 growth hormone 1 0.281153
CHRM2 cholinergic receptor, muscarinic 2 0.279724
FYB FYN binding protein 0.275801
ROM1 retinal outer segment membrane protein 1 0.275801
VDAC1 voltage-dependent anion channel 1 0.269398
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.264077
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.258064
MX2 MX dynamin-like GTPase 2 0.253831
BCHE butyrylcholinesterase 0.252422
STAB2 stabilin 2 0.246448
TMPRSS15 transmembrane protease, serine 15 0.243645
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.241546
CES1 carboxylesterase 1 0.238054
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.236312
NFE2 nuclear factor, erythroid 2 0.235964
CAT catalase 0.231102
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.226262
CD83 CD83 molecule 0.225573
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.224196
ASPN asporin 0.223165
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.219057
MNX1 motor neuron and pancreas homeobox 1 0.218715
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.215314
IL17A interleukin 17A 0.212102
GYPA glycophorin A (MNS blood group) 0.209248
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.207912
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.203933
DEFB1 defensin, beta 1 0.201308
GAB2 GRB2-associated binding protein 2 0.200331
CXCR2 chemokine (C-X-C motif) receptor 2 0.199033
MEGF6 multiple EGF-like-domains 6 0.196139
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.19582
CTNND1 catenin (cadherin-associated protein), delta 1 0.189551
FOXG1 forkhead box G1 0.189551
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.187113
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.18651
MAP1B microtubule-associated protein 1B 0.18621
CIB1 calcium and integrin binding 1 (calmyrin) 0.185612
OCA2 oculocutaneous albinism II 0.185612
TLR5 toll-like receptor 5 0.183541
NKX2-1 NK2 homeobox 1 0.180652
PRIMA1 proline rich membrane anchor 1 0.179239
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.178682
UBC ubiquitin C 0.176485
ALB albumin 0.175411
MSMB microseminoprotein, beta- 0.171785
TAS1R3 taste receptor, type 1, member 3 0.171286
RPS27A ribosomal protein S27a 0.170544
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.168148
TLR3 toll-like receptor 3 0.167452
TOX thymocyte selection-associated high mobility group box 0.165655
KRT10 keratin 10, type I 0.163729
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.160203
IRF3 interferon regulatory factor 3 0.146085
DNAH8 dynein, axonemal, heavy chain 8 0.144083
TCHH trichohyalin 0.141085
ADORA1 adenosine A1 receptor 0.141026
PADI4 peptidyl arginine deiminase, type IV 0.140438
GLO1 glyoxalase I 0.140323
CXCL5 chemokine (C-X-C motif) ligand 5 0.139817
CXCL2 chemokine (C-X-C motif) ligand 2 0.139687
CFD complement factor D (adipsin) 0.139505
ACO2 aconitase 2, mitochondrial 0.139342
LGALS7 lectin, galactoside-binding, soluble, 7 0.139011
CDC25A cell division cycle 25A 0.138706
G6PD glucose-6-phosphate dehydrogenase 0.13818
CCL20 chemokine (C-C motif) ligand 20 0.137386
LCT lactase 0.13568
DDIT3 DNA-damage-inducible transcript 3 0.135129
CAMP cathelicidin antimicrobial peptide 0.133887
CDC42 cell division cycle 42 0.132469
CCR7 chemokine (C-C motif) receptor 7 0.130811
CCR2 chemokine (C-C motif) receptor 2 0.12843
NOS2 nitric oxide synthase 2, inducible 0.12712
CBS cystathionine-beta-synthase 0.126631