plastid-encoded plastid RNA polymerase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition. (Gene Ontology, GO_0000427)
External Link http://amigo.geneontology.org/amigo/term/GO:0000427
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Genes

695 proteins co-occuring with the plastid-encoded plastid RNA polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PGC progastricsin (pepsinogen C) 2.718
LAP3 leucine aminopeptidase 3 2.647
PEPD peptidase D 2.584
ANPEP alanyl (membrane) aminopeptidase 2.533
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.364
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.255
PGM2 phosphoglucomutase 2 2.201
PEBP1 phosphatidylethanolamine binding protein 1 2.198
CTSD cathepsin D 2.18
PGM1 phosphoglucomutase 1 2.179
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.072
PGA4 pepsinogen 4, group I (pepsinogen A) 1.944
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.868
CTSS cathepsin S 1.859
PGA3 pepsinogen 3, group I (pepsinogen A) 1.858
GRN granulin 1.845
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.825
PGM3 phosphoglucomutase 3 1.813
DNPEP aspartyl aminopeptidase 1.781
DAZAP2 DAZ associated protein 2 1.78
SLPI secretory leukocyte peptidase inhibitor 1.762
CTSB cathepsin B 1.752
FBF1 Fas (TNFRSF6) binding factor 1 1.715
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 1.686
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.668
HTRA1 HtrA serine peptidase 1 1.666
LAMP1 lysosomal-associated membrane protein 1 1.658
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.651
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.649
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.644
PGA5 pepsinogen 5, group I (pepsinogen A) 1.633
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.631
ARX aristaless related homeobox 1.63
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.627
PGPEP1 pyroglutamyl-peptidase I 1.613
GLO1 glyoxalase I 1.583
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2 1.577
SQSTM1 sequestosome 1 1.572
ATG7 autophagy related 7 1.549
TMSB10 thymosin beta 10 1.544
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.522
CTSE cathepsin E 1.507
CTSL cathepsin L 1.504
AK2 adenylate kinase 2 1.495
PTBP2 polypyrimidine tract binding protein 2 1.48
AGBL2 ATP/GTP binding protein-like 2 1.476
BECN1 beclin 1, autophagy related 1.473
GNPDA1 glucosamine-6-phosphate deaminase 1 1.472
DERA deoxyribose-phosphate aldolase (putative) 1.465
RNF183 ring finger protein 183 1.462
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.459
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.443
DSPP dentin sialophosphoprotein 1.437
ZC3H12D zinc finger CCCH-type containing 12D 1.426
GSR glutathione reductase 1.424
ANXA5 annexin A5 1.422
SORD sorbitol dehydrogenase 1.422
CELA3A chymotrypsin-like elastase family, member 3A 1.408
ATG5 autophagy related 5 1.404
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.396
B2M beta-2-microglobulin 1.374
MAST4 microtubule associated serine/threonine kinase family member 4 1.368
PPY pancreatic polypeptide 1.367
HSPE1 heat shock 10kDa protein 1 1.362
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.36
PDF peptide deformylase (mitochondrial) 1.357
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.354
PXDNL peroxidasin-like 1.352
PXDN peroxidasin 1.35
MAP1S microtubule-associated protein 1S 1.345
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.329
IFNG interferon, gamma 1.321
MMRN2 multimerin 2 1.32
METAP1 methionyl aminopeptidase 1 1.315
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.314
CTRB1 chymotrypsinogen B1 1.308
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.303
HEMK1 HemK methyltransferase family member 1 1.303
CTRB2 chymotrypsinogen B2 1.292
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.292
SOD1 superoxide dismutase 1, soluble 1.29
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.288
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.284
LDHA lactate dehydrogenase A 1.282
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.279
ENO1 enolase 1, (alpha) 1.278
CTNS cystinosin, lysosomal cystine transporter 1.264
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 1.263
GUK1 guanylate kinase 1 1.255
ULK1 unc-51 like autophagy activating kinase 1 1.253
GLMN glomulin, FKBP associated protein 1.253
XYLB xylulokinase homolog (H. influenzae) 1.245
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.244
LARS1 leucyl-tRNA synthetase 1 1.243
GANC glucosidase, alpha; neutral C 1.236
INS insulin 1.234
CD4 CD4 molecule 1.232
NALF2 NALCN channel auxiliary factor 2 1.226
UBL4A ubiquitin-like 4A 1.226
AK3 adenylate kinase 3 1.223
ESD esterase D 1.212
AK1 adenylate kinase 1 1.208
TNF tumor necrosis factor 1.204
NT5C 5', 3'-nucleotidase, cytosolic 1.2
LCE1C late cornified envelope 1C 1.199
RBM46 RNA binding motif protein 46 1.192
MAP1B microtubule-associated protein 1B 1.19
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.188
TYRP1 tyrosinase-related protein 1 1.188
COPS2 COP9 signalosome subunit 2 1.184
CD8A CD8a molecule 1.176
FUCA1 fucosidase, alpha-L- 1, tissue 1.175
NFS1 NFS1 cysteine desulfurase 1.174
CCNQ cyclin Q 1.166
HCRTR1 hypocretin (orexin) receptor 1 1.165
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3 1.158
MFSD6 major facilitator superfamily domain containing 6 1.154
DEFB1 defensin, beta 1 1.151
TBX22 T-box 22 1.15
EPHA2 EPH receptor A2 1.15
CTTNBP2 cortactin binding protein 2 1.149
NOA1 nitric oxide associated 1 1.142
AMY2B amylase, alpha 2B (pancreatic) 1.141
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 1.14
AMY2A amylase, alpha 2A (pancreatic) 1.138
TPI1 triosephosphate isomerase 1 1.131
VCX3A variable charge, X-linked 3A 1.128
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 1.126
GRIK5 glutamate receptor, ionotropic, kainate 5 1.124
HCRT hypocretin (orexin) neuropeptide precursor 1.121
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 1.116
SEBOX SEBOX homeobox 1.112
LCE1A late cornified envelope 1A 1.112
AMY1B amylase, alpha 1B (salivary) 1.111
MLKL mixed lineage kinase domain-like 1.104
NCOA4 nuclear receptor coactivator 4 1.101
NBR1 neighbor of BRCA1 gene 1 1.098
LCE1B late cornified envelope 1B 1.085
APP amyloid beta (A4) precursor protein 1.084
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.082
TBL1X transducin (beta)-like 1X-linked 1.082
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.072
TXN2 thioredoxin 2 1.071
CYCS cytochrome c, somatic 1.067
ASRGL1 asparaginase like 1 1.067
ACP3 acid phosphatase 3 1.064
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.055
UCK2 uridine-cytidine kinase 2 1.052
LAMP2 lysosomal-associated membrane protein 2 1.05
OPTC opticin 1.049
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.048
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.046
NPS neuropeptide S 1.046
GALE UDP-galactose-4-epimerase 1.046
NEGR1 neuronal growth regulator 1 1.04
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.039
NPTX2 neuronal pentraxin II 1.038
CTRL chymotrypsin-like 1.034
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 1.031
IL10 interleukin 10 1.027
CPB1 carboxypeptidase B1 (tissue) 1.025
ISCU iron-sulfur cluster assembly enzyme 1.022
CPZ carboxypeptidase Z 1.021
IL6 interleukin 6 1.011
RAD51 RAD51 recombinase 1.01
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.008
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.0
MTERF1 mitochondrial transcription termination factor 1 0.997
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.993
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.993
GABARAPL1 GABA(A) receptor-associated protein like 1 0.992
PRTN3 proteinase 3 0.99
MMP2 matrix metallopeptidase 2 0.986
TALDO1 transaldolase 1 0.984
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 0.982
CSN1S1 casein alpha s1 0.981
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.98
ACY1 aminoacylase 1 0.976
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.975
DPP4 dipeptidyl-peptidase 4 0.973
PCSK1 proprotein convertase subtilisin/kexin type 1 0.973
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.973
GGT6 gamma-glutamyltransferase 6 0.973
PRTG protogenin 0.973
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.972
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.971
YME1L1 YME1-like 1 ATPase 0.97
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.969
MTERF2 mitochondrial transcription termination factor 2 0.966
CLSTN1 calsyntenin 1 0.966
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.964
ERBB2 erb-b2 receptor tyrosine kinase 2 0.964
HSPA4 heat shock 70kDa protein 4 0.963
PFAS phosphoribosylformylglycinamidine synthase 0.96
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.959
MTERF3 mitochondrial transcription termination factor 3 0.958
LOC102724560 cystathionine beta-synthase 0.958
CD274 CD274 molecule 0.953
AK4 adenylate kinase 4 0.951
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.939
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.939
YBX3 Y box binding protein 3 0.938
SMLR1 small leucine-rich protein 1 0.936
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.935
LGALS3 lectin, galactoside-binding, soluble, 3 0.934
PPP4C protein phosphatase 4, catalytic subunit 0.933
PLG plasminogen 0.928
FLG2 filaggrin family member 2 0.926
LHB luteinizing hormone beta polypeptide 0.925
AMBP alpha-1-microglobulin/bikunin precursor 0.925
HBB hemoglobin, beta 0.924
MGAM maltase-glucoamylase 0.923
FLG filaggrin 0.923
CBLIF cobalamin binding intrinsic factor 0.922
BHMT2 betaine--homocysteine S-methyltransferase 2 0.92
SART1 squamous cell carcinoma antigen recognized by T cells 0.92
PRODH proline dehydrogenase (oxidase) 1 0.919
ENO2 enolase 2 (gamma, neuronal) 0.918
SEC14L3 SEC14-like 3 (S. cerevisiae) 0.918
NUBP2 nucleotide binding protein 2 0.914
WIPI2 WD repeat domain, phosphoinositide interacting 2 0.912
TMEM192 transmembrane protein 192 0.911
SEPHS1 selenophosphate synthetase 1 0.908
ZFHX2 zinc finger homeobox 2 0.908
ATG14 autophagy related 14 0.907
AKTIP AKT interacting protein 0.906
TP53 tumor protein p53 0.906
CCNY cyclin Y 0.902
CD1D CD1d molecule 0.901
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.9
ADCY8 adenylate cyclase 8 (brain) 0.898
LOX lysyl oxidase 0.896
ATG12 autophagy related 12 0.894
PELI1 pellino E3 ubiquitin protein ligase 1 0.894
HEXB hexosaminidase B (beta polypeptide) 0.893
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.891
GGT7 gamma-glutamyltransferase 7 0.891
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.891
EGFR epidermal growth factor receptor 0.887
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.887
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.886
CCDC50 coiled-coil domain containing 50 0.885
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.885
PRKCSH protein kinase C substrate 80K-H 0.884
CHD7 chromodomain helicase DNA binding protein 7 0.883
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.882
FTMT ferritin mitochondrial 0.88
GUSB glucuronidase, beta 0.877
FOS FBJ murine osteosarcoma viral oncogene homolog 0.872
CFLAR CASP8 and FADD-like apoptosis regulator 0.869
RIPK3 receptor-interacting serine-threonine kinase 3 0.86
DUOXA1 dual oxidase maturation factor 1 0.86
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.859
ATP5IF1 ATP synthase inhibitory factor subunit 1 0.859
ASCL3 achaete-scute family bHLH transcription factor 3 0.856
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.856
LRRC36 leucine rich repeat containing 36 0.855
EGF epidermal growth factor 0.855
ZNF410 zinc finger protein 410 0.854
FTH1 ferritin, heavy polypeptide 1 0.854
SNX5 sorting nexin 5 0.853
CST5 cystatin D 0.851
PKM pyruvate kinase, muscle 0.85
CIAO2B cytosolic iron-sulfur assembly component 2B 0.849
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.849
IL1B interleukin 1, beta 0.848
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.848
HAGH hydroxyacylglutathione hydrolase 0.844
RPS2 ribosomal protein S2 0.844
WARS1 tryptophanyl-tRNA synthetase 1 0.843
ANXA1 annexin A1 0.842
PECR peroxisomal trans-2-enoyl-CoA reductase 0.838
LDLR low density lipoprotein receptor 0.838
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.837
PTPRJ protein tyrosine phosphatase, receptor type, J 0.835
OPRM1 opioid receptor, mu 1 0.834
BCL2 B-cell CLL/lymphoma 2 0.834
PARP1 poly (ADP-ribose) polymerase 1 0.833
NTS neurotensin 0.832
RAB7A RAB7A, member RAS oncogene family 0.831
TGM1 transglutaminase 1 0.829
GC group-specific component (vitamin D binding protein) 0.826
F13B coagulation factor XIII, B polypeptide 0.825
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.825
ATG13 autophagy related 13 0.824
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.824
IL2 interleukin 2 0.821
NLRP3 NLR family, pyrin domain containing 3 0.821
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.82
RRM1 ribonucleotide reductase M1 0.82
DMBT1 deleted in malignant brain tumors 1 0.819
MB myoglobin 0.818
TFEB transcription factor EB 0.817
DUT deoxyuridine triphosphatase 0.816
CRYBG3 beta-gamma crystallin domain containing 3 0.815
MOXD1 monooxygenase, DBH-like 1 0.813
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.811
CNIH2 cornichon family AMPA receptor auxiliary protein 2 0.811
PRH1 proline-rich protein HaeIII subfamily 1 0.809
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.808
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.808
RBKS ribokinase 0.807
S100A2 S100 calcium binding protein A2 0.805
ASPN asporin 0.803
DNAH8 dynein, axonemal, heavy chain 8 0.802
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.802
DIABLO diablo, IAP-binding mitochondrial protein 0.797
PRH2 proline-rich protein HaeIII subfamily 2 0.796
TTC33 tetratricopeptide repeat domain 33 0.793
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.788
GDPGP1 GDP-D-glucose phosphorylase 1 0.785
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.785
KLK6 kallikrein-related peptidase 6 0.784
APLF aprataxin and PNKP like factor 0.783
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 0.782
DPP7 dipeptidyl-peptidase 7 0.78
RNF7 ring finger protein 7 0.78
TRO trophinin 0.78
RIPK2 receptor-interacting serine-threonine kinase 2 0.779
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.778
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.777
TMEM37 transmembrane protein 37 0.776
KCTD11 potassium channel tetramerization domain containing 11 0.775
CHIT1 chitinase 1 (chitotriosidase) 0.773
NPC2 Niemann-Pick disease, type C2 0.772
PGLYRP2 peptidoglycan recognition protein 2 0.772
FTL ferritin, light polypeptide 0.769
ESX1 ESX homeobox 1 0.769
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.768
EGLN2 egl-9 family hypoxia-inducible factor 2 0.767
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.766
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.765
PPT1 palmitoyl-protein thioesterase 1 0.764
TRIM32 tripartite motif containing 32 0.762
VDAC1 voltage-dependent anion channel 1 0.762
KNG1 kininogen 1 0.762
MIER1 mesoderm induction early response 1, transcriptional regulator 0.761
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.76
RPS17 ribosomal protein S17 0.76
NISCH nischarin 0.759
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.758
C8A complement component 8, alpha polypeptide 0.758
ADCY10 adenylate cyclase 10 (soluble) 0.757
CCKAR cholecystokinin A receptor 0.754
GM2A GM2 ganglioside activator 0.754
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.754
HSH2D hematopoietic SH2 domain containing 0.754
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.754
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.753
SELENOI selenoprotein I 0.752
CELA3B chymotrypsin-like elastase family, member 3B 0.752
C5 complement component 5 0.751
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.751
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.75
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.748
SMOX spermine oxidase 0.745
ADA adenosine deaminase 0.745
PRKN parkin RBR E3 ubiquitin protein ligase 0.744
BDNF brain-derived neurotrophic factor 0.743
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 0.743
M6PR mannose-6-phosphate receptor (cation dependent) 0.742
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.741
ZNF521 zinc finger protein 521 0.741
DEFB104B defensin, beta 104B 0.74
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.74
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 0.739
UCK1 uridine-cytidine kinase 1 0.735
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.734
CLCN5 chloride channel, voltage-sensitive 5 0.733
TPH1 tryptophan hydroxylase 1 0.73
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.73
COPS3 COP9 signalosome subunit 3 0.728
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.727
CFB complement factor B 0.726
GALM galactose mutarotase (aldose 1-epimerase) 0.725
TTC14 tetratricopeptide repeat domain 14 0.724
SLC45A3 solute carrier family 45, member 3 0.723
DEFB104A defensin, beta 104A 0.721
XAGE1A X antigen family member 1A 0.72
CLN5 ceroid-lipofuscinosis, neuronal 5 0.719
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.718
GPR15 G protein-coupled receptor 15 0.717
IFNA1 interferon, alpha 1 0.717
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.717
ACTA1 actin, alpha 1, skeletal muscle 0.716
FOXP3 forkhead box P3 0.715
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 0.715
FDX1 ferredoxin 1 0.714
ADSL adenylosuccinate lyase 0.714
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.714
NOCT nocturnin 0.713
TGFB1 transforming growth factor, beta 1 0.712
UCKL1 uridine-cytidine kinase 1-like 1 0.712
ACSF2 acyl-CoA synthetase family member 2 0.711
RAB5A RAB5A, member RAS oncogene family 0.711
FAM184A family with sequence similarity 184, member A 0.709
AARS1 alanyl-tRNA synthetase 1 0.709
MAPK3 mitogen-activated protein kinase 3 0.708
GGT1 gamma-glutamyltransferase 1 0.708
TFRC transferrin receptor 0.708
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.707
QDPR quinoid dihydropteridine reductase 0.706
RPIA ribose 5-phosphate isomerase A 0.706
STRADA STE20-related kinase adaptor alpha 0.706
RB1CC1 RB1-inducible coiled-coil 1 0.703
TLR4 toll-like receptor 4 0.703
SYNJ2BP synaptojanin 2 binding protein 0.702
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.701
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 0.701
BIRC5 baculoviral IAP repeat containing 5 0.699
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.699
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.699
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.699
SNX6 sorting nexin 6 0.699
MTFMT mitochondrial methionyl-tRNA formyltransferase 0.693
PELI3 pellino E3 ubiquitin protein ligase family member 3 0.692
DEFB103A defensin, beta 103A 0.69
SCGB1D2 secretoglobin, family 1D, member 2 0.69
GAST gastrin 0.689
CDK16 cyclin-dependent kinase 16 0.689
GLRX5 glutaredoxin 5 0.685
IL17F interleukin 17F 0.684
THOP1 thimet oligopeptidase 1 0.684
LTA4H leukotriene A4 hydrolase 0.682
PEBP4 phosphatidylethanolamine-binding protein 4 0.679
PRNP prion protein 0.678
RGMA repulsive guidance molecule family member a 0.677
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.676
PRSS58 protease, serine, 58 0.674
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.673
BACE1 beta-site APP-cleaving enzyme 1 0.673
LIPF lipase, gastric 0.673
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.673
UCMA upper zone of growth plate and cartilage matrix associated 0.671
GMDS GDP-mannose 4,6-dehydratase 0.671
DHFR dihydrofolate reductase 0.67
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.67
MAGEA1 melanoma antigen family A1 0.669
PTPRC protein tyrosine phosphatase, receptor type, C 0.669
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.669
CD44 CD44 molecule (Indian blood group) 0.669
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.668
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.668
PACRG PARK2 co-regulated 0.668
DYNLRB1 dynein, light chain, roadblock-type 1 0.666
ATG101 autophagy related 101 0.664
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.663
CAB39 calcium binding protein 39 0.663
AMBRA1 autophagy/beclin-1 regulator 1 0.661
BAX BCL2-associated X protein 0.661
CPNE1 copine I 0.661
FN1 fibronectin 1 0.654
MMP25 matrix metallopeptidase 25 0.654
UGDH UDP-glucose 6-dehydrogenase 0.653
MMP9 matrix metallopeptidase 9 0.653
ZFY zinc finger protein, Y-linked 0.653
TEX264 testis expressed 264 0.652
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.652
IL2RB interleukin 2 receptor, beta 0.651
GALNS galactosamine (N-acetyl)-6-sulfatase 0.65
NAGA N-acetylgalactosaminidase, alpha- 0.65
CLN3 ceroid-lipofuscinosis, neuronal 3 0.65
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.65
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.65
ERVW-1 endogenous retrovirus group W, member 1 0.647
PRMT3 protein arginine methyltransferase 3 0.647
RCC2 regulator of chromosome condensation 2 0.647
EHD1 EH-domain containing 1 0.645
NCS1 neuronal calcium sensor 1 0.645
HDAC9 histone deacetylase 9 0.644
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B 0.644
ADSS2 adenylosuccinate synthase 2 0.643
REXO5 RNA exonuclease 5 0.641
GLRX glutaredoxin (thioltransferase) 0.641
PIF1 PIF1 5'-to-3' DNA helicase 0.639
ZNF175 zinc finger protein 175 0.638
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.638
AOC3 amine oxidase, copper containing 3 0.635
MAPK8 mitogen-activated protein kinase 8 0.635
CD33 CD33 molecule 0.634
IDE insulin-degrading enzyme 0.634
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.633
BIRC7 baculoviral IAP repeat containing 7 0.633
ACSL4 acyl-CoA synthetase long-chain family member 4 0.633
SYNRG synergin, gamma 0.632
IFNB1 interferon, beta 1, fibroblast 0.632
LTF lactotransferrin 0.631
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 0.63
ACO1 aconitase 1, soluble 0.629
HLA-A major histocompatibility complex, class I, A 0.626
NRG2 neuregulin 2 0.626
LDHD lactate dehydrogenase D 0.625
PRL prolactin 0.624
KLK11 kallikrein-related peptidase 11 0.623
POTEF POTE ankyrin domain family, member F 0.623
LCN2 lipocalin 2 0.622
POU2F3 POU class 2 homeobox 3 0.622
IL4 interleukin 4 0.621
POMC proopiomelanocortin 0.62
GGTLC3 gamma-glutamyltransferase light chain 3 0.619
LALBA lactalbumin, alpha- 0.619
IGF1 insulin-like growth factor 1 (somatomedin C) 0.618
IGBP1 immunoglobulin (CD79A) binding protein 1 0.618
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.617
CA2 carbonic anhydrase II 0.616
NAGLU N-acetylglucosaminidase, alpha 0.614
GCDH glutaryl-CoA dehydrogenase 0.613
VIM vimentin 0.613
YDJC YdjC homolog (bacterial) 0.613
SOD2 superoxide dismutase 2, mitochondrial 0.612
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.611
SNCB synuclein, beta 0.611
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.611
BCL2L1 BCL2-like 1 0.61
IGF2R insulin-like growth factor 2 receptor 0.609
H2BC21 H2B clustered histone 21 0.609
S100A6 S100 calcium binding protein A6 0.608
PHF1 PHD finger protein 1 0.608
GABARAP GABA(A) receptor-associated protein 0.608
PCDH8 protocadherin 8 0.607
IREB2 iron-responsive element binding protein 2 0.607
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.607
VCAN versican 0.606
CTSG cathepsin G 0.606
SYN3 synapsin III 0.602
ESR2 estrogen receptor 2 (ER beta) 0.6
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.599
TBK1 TANK-binding kinase 1 0.599
FLII flightless I homolog (Drosophila) 0.598
SMC6 structural maintenance of chromosomes 6 0.597
MYH14 myosin, heavy chain 14, non-muscle 0.597
SNX2 sorting nexin 2 0.595
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.595
RAB43 RAB43, member RAS oncogene family 0.595
H1-0 H1.0 linker histone 0.595
CREB1 cAMP responsive element binding protein 1 0.593
STX17 syntaxin 17 0.593
PEDS1 plasmanylethanolamine desaturase 1 0.592
HLA-B major histocompatibility complex, class I, B 0.591
PMEL premelanosome protein 0.59
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.59
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.59
KARS1 lysyl-tRNA synthetase 1 0.589
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.589
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.588
SCIN scinderin 0.588
FAR2 fatty acyl CoA reductase 2 0.587
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.586
MRI1 methylthioribose-1-phosphate isomerase 1 0.586
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.585
JUN jun proto-oncogene 0.585
CCL2 chemokine (C-C motif) ligand 2 0.584
TDO2 tryptophan 2,3-dioxygenase 0.584
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like 0.583
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.583
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.583
MCEE methylmalonyl CoA epimerase 0.582
HTRA2 HtrA serine peptidase 2 0.582
CD69 CD69 molecule 0.582
PHGDH phosphoglycerate dehydrogenase 0.581
ACE angiotensin I converting enzyme 0.579
RAB9A RAB9A, member RAS oncogene family 0.578
BACE2 beta-site APP-cleaving enzyme 2 0.577
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.576
TRIM5 tripartite motif containing 5 0.576
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.576
SOCS4 suppressor of cytokine signaling 4 0.575
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.574
NRDC nardilysin convertase 0.573
PRDX5 peroxiredoxin 5 0.571
CPOX coproporphyrinogen oxidase 0.571
TET1 tet methylcytosine dioxygenase 1 0.57
LGMN legumain 0.57
VWF von Willebrand factor 0.57
CGAS cyclic GMP-AMP synthase 0.569
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.568
DPP6 dipeptidyl-peptidase 6 0.567
MPZ myelin protein zero 0.564
AKR1C2 aldo-keto reductase family 1, member C2 0.563
GBA1 glucosylceramidase beta 1 0.562
C1QBP complement component 1, q subcomponent binding protein 0.562
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 0.562
MMP8 matrix metallopeptidase 8 0.562
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.561
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.561
AFM afamin 0.561
CDA cytidine deaminase 0.56
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.559
THBS1 thrombospondin 1 0.559
IDO1 indoleamine 2,3-dioxygenase 1 0.559
PRKCA protein kinase C, alpha 0.558
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.558
TRIM3 tripartite motif containing 3 0.557
MMP11 matrix metallopeptidase 11 0.557
CTAG1B cancer/testis antigen 1B 0.557
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.557
ECM1 extracellular matrix protein 1 0.557
AGMAT agmatine ureohydrolase (agmatinase) 0.557
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.557
FGF13 fibroblast growth factor 13 0.556
PCDHGA2 protocadherin gamma subfamily A, 2 0.556
DCAKD dephospho-CoA kinase domain containing 0.555
DRAM1 DNA-damage regulated autophagy modulator 1 0.555
HBA2 hemoglobin, alpha 2 0.555
AARS2 alanyl-tRNA synthetase 2, mitochondrial 0.553
PAX9 paired box 9 0.552
CTSZ cathepsin Z 0.552
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 0.551
TH tyrosine hydroxylase 0.549
NPTXR neuronal pentraxin receptor 0.549
PLAT plasminogen activator, tissue 0.548
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.548
CAPN1 calpain 1, (mu/I) large subunit 0.548
KRT15 keratin 15, type I 0.547
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.547
STK11 serine/threonine kinase 11 0.545
NAPSA napsin A aspartic peptidase 0.545
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.544
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.544
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.544
CS citrate synthase 0.544
CSRP1 cysteine and glycine-rich protein 1 0.543
FADD Fas (TNFRSF6)-associated via death domain 0.543
AGRN agrin 0.542
CD300C CD300c molecule 0.541
GPX4 glutathione peroxidase 4 0.541
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.54
ENGASE endo-beta-N-acetylglucosaminidase 0.54
OCRL oculocerebrorenal syndrome of Lowe 0.539
PRDX2 peroxiredoxin 2 0.539
GNMT glycine N-methyltransferase 0.538
GP2 glycoprotein 2 (zymogen granule membrane) 0.537
NGFR nerve growth factor receptor 0.536
PCDHB16 protocadherin beta 16 0.534
A2M alpha-2-macroglobulin 0.534
GLUL glutamate-ammonia ligase 0.533
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 0.532
IGLL5 immunoglobulin lambda-like polypeptide 5 0.532
PEDS1-UBE2V1 PEDS1-UBE2V1 readthrough 0.529
ORM2 orosomucoid 2 0.528
UVRAG UV radiation resistance associated 0.528
CRY1 cryptochrome circadian clock 1 0.528
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.527
CA1 carbonic anhydrase I 0.526
GPKOW G patch domain and KOW motifs 0.525
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.523
CIDEB cell death-inducing DFFA-like effector b 0.522
TLR2 toll-like receptor 2 0.521
RHAG Rh-associated glycoprotein 0.521
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.52
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.52
CD163 CD163 molecule 0.519
TREH trehalase (brush-border membrane glycoprotein) 0.519
ATP5MC3 ATP synthase membrane subunit c locus 3 0.519
LYZL4 lysozyme-like 4 0.518
RAB4B RAB4B, member RAS oncogene family 0.518
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 0.517
CD276 CD276 molecule 0.517
HMGA2 high mobility group AT-hook 2 0.516
HBE1 hemoglobin, epsilon 1 0.516
AMDHD1 amidohydrolase domain containing 1 0.515
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.515
OAF OAF homolog (Drosophila) 0.514
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.514
SLC51A solute carrier family 51, alpha subunit 0.514
GKN1 gastrokine 1 0.513
GOLT1A golgi transport 1A 0.512
PEX13 peroxisomal biogenesis factor 13 0.511
PCBP2 poly(rC) binding protein 2 0.509
NPPA natriuretic peptide A 0.509
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.508
SPMIP8 sperm microtubule inner protein 8 0.508
A1BG alpha-1-B glycoprotein 0.508
EEF2 eukaryotic translation elongation factor 2 0.507
KLK1 kallikrein 1 0.507
PCNA proliferating cell nuclear antigen 0.507
DAGLA diacylglycerol lipase, alpha 0.506
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.506
ANTXR2 anthrax toxin receptor 2 0.505
DPPA3 developmental pluripotency associated 3 0.505
LY86 lymphocyte antigen 86 0.504
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.504
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.504
NPY neuropeptide Y 0.503
CPA6 carboxypeptidase A6 0.503
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.502
SEPTIN2 septin 2 0.502
GRIK1 glutamate receptor, ionotropic, kainate 1 0.502
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.502
TAC1 tachykinin, precursor 1 0.501
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.501
TUBB2A tubulin, beta 2A class IIa 0.501
CALR calreticulin 0.501
BMP2 bone morphogenetic protein 2 0.501
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.5