platelet dense tubular network Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin. (Gene Ontology, GO_0031094)
External Link http://amigo.geneontology.org/amigo/term/GO:0031094
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Genes

11 proteins localized to the platelet dense tubular network cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
DMTN dematin actin binding protein
EHD1 EH-domain containing 1
F2R coagulation factor II (thrombin) receptor
IRAG1 inositol 1,4,5-triphosphate receptor associated 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5