platelets Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

420 genes co-occuring with the biological term platelets in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABI1 abl-interactor 1
ACLY ATP citrate lyase
ACTA1 actin, alpha 1, skeletal muscle
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADA adenosine deaminase
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY3 adenylate cyclase 3
ADRA2A adrenoceptor alpha 2A
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX12 arachidonate 12-lipoxygenase
ANKRD26 ankyrin repeat domain 26
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ASGR1 asialoglycoprotein receptor 1
ASGR2 asialoglycoprotein receptor 2
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BACE1 beta-site APP-cleaving enzyme 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BDNF brain-derived neurotrophic factor
BSG basigin (Ok blood group)
BTK Bruton agammaglobulinemia tyrosine kinase
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C6ORF25 chromosome 6 open reading frame 25
C9 complement component 9
CALR calreticulin
CAPN1 calpain 1, (mu/I) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CD151 CD151 molecule (Raph blood group)
CD209 CD209 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD70 CD70 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CEL carboxyl ester lipase
CFH complement factor H
CFP complement factor properdin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CIB1 calcium and integrin binding 1 (calmyrin)
CLEC1B C-type lectin domain family 1, member B
CLEC2B C-type lectin domain family 2, member B
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COL18A1 collagen, type XVIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COX1
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CSNK2B casein kinase 2, beta polypeptide
CTGF connective tissue growth factor
CTSG cathepsin G
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DCN decorin
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DIAPH1 diaphanous-related formin 1
DMD dystrophin
DMTN dematin actin binding protein
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
EFNB1 ephrin-B1
EGR1 early growth response 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA4 EPH receptor A4
EPHB1 EPH receptor B1
ERO1L ERO1-like (S. cerevisiae)
ESR2 estrogen receptor 2 (ER beta)
F10 coagulation factor X
F11 coagulation factor XI
F11R F11 receptor
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FAS Fas cell surface death receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FER fer (fps/fes related) tyrosine kinase
FERMT3 fermitin family member 3
FES FES proto-oncogene, tyrosine kinase
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FGG fibrinogen gamma chain
FHIT fragile histidine triad
FHOD1 formin homology 2 domain containing 1
FLNA filamin A, alpha
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FMR1 fragile X mental retardation 1
FOXG1 forkhead box G1
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAS6 growth arrest-specific 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GDF2 growth differentiation factor 2
GGT1 gamma-glutamyltransferase 1
GJA4 gap junction protein, alpha 4, 37kDa
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP6 glycoprotein VI (platelet)
GP9 glycoprotein IX (platelet)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX4 glutathione peroxidase 4
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HCLS1 hematopoietic cell-specific Lyn substrate 1
HFE hemochromatosis
HMGB1 high mobility group box 1
HPSE heparanase
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTRA2 HtrA serine peptidase 2
HYAL2 hyaluronoglucosaminidase 2
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFNA1 interferon, alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IL17A interleukin 17A
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
ILK integrin-linked kinase
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INSR insulin receptor
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA6 integrin, alpha 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KDR kinase insert domain receptor
KNG1 kininogen 1
KRT18 keratin 18, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LASP1 LIM and SH3 protein 1
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC32 leucine rich repeat containing 32
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MIR150 microRNA 150
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MPL MPL proto-oncogene, thrombopoietin receptor
MSN moesin
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK myosin light chain kinase
NCF1C neutrophil cytosolic factor 1C pseudogene
NCF2 neutrophil cytosolic factor 2
ND1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NISCH nischarin
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY neuropeptide Y
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1I2 nuclear receptor subfamily 1, group I, member 2
OCRL oculocerebrorenal syndrome of Lowe
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI2 ORAI calcium release-activated calcium modulator 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PANX1 pannexin 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE5A phosphodiesterase 5A, cGMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PDIA3 protein disulfide isomerase family A, member 3
PDIA6 protein disulfide isomerase family A, member 6
PDPN podoplanin
PEAR1 platelet endothelial aggregation receptor 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKDCC protein kinase domain containing, cytoplasmic
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB2 phospholipase C, beta 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLVAP plasmalemma vesicle associated protein
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKG1 protein kinase, cGMP-dependent, type I
PRL prolactin
PRNP prion protein
PROS1 protein S (alpha)
PRTN3 proteinase 3
PSEN1 presenilin 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTX3 pentraxin 3, long
PXN paxillin
RAB27A RAB27A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RAP2B RAP2B, member of RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM8A RNA binding motif protein 8A
RBP4 retinol binding protein 4, plasma
RELN reelin
RETN resistin
RGS10 regulator of G-protein signaling 10
RGS18 regulator of G-protein signaling 18
RGS7 regulator of G-protein signaling 7
RHOA ras homolog family member A
RHOG ras homolog family member G
RNF181 ring finger protein 181
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS19 ribosomal protein S19
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
RXRB retinoid X receptor, beta
SAA1 serum amyloid A1
SDC4 syndecan 4
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPT11 septin 11
SEPT4 septin 4
SEPT8 septin 8
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLA2 Src-like-adaptor 2
SLC16A4 solute carrier family 16, member 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMAD2 SMAD family member 2
SNAP23 synaptosomal-associated protein, 23kDa
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
STX11 syntaxin 11
STX1A syntaxin 1A (brain)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
SYTL4 synaptotagmin-like 4
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TACR3 tachykinin receptor 3
TBXA2R thromboxane A2 receptor
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
THPO thrombopoietin
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRAF4 TNF receptor-associated factor 4
TREML1 triggering receptor expressed on myeloid cells-like 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSPO translocator protein (18kDa)
TUBB1 tubulin, beta 1 class VI
TXNDC15 thioredoxin domain containing 15
UNC13D unc-13 homolog D (C. elegans)
UTS2R urotensin 2 receptor
VAMP3 vesicle-associated membrane protein 3
VAMP8 vesicle-associated membrane protein 8
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCL vinculin
VEGFA vascular endothelial growth factor A
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta