pleurisy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A pleural disease that is characterized by inflammation of the pleura, the lining of the pleural cavity surrounding the lungs. (Human Disease Ontology, DOID_10247)
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Genes

110 genes co-occuring with the disease pleurisy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ADA adenosine deaminase 1.86278
KNG1 kininogen 1 1.68498
MPO myeloperoxidase 1.37338
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.29877
IL1B interleukin 1, beta 1.28872
ALOX5 arachidonate 5-lipoxygenase 1.23169
KIAA0101 KIAA0101 1.21478
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.17335
TNF tumor necrosis factor 1.06102
PTGES prostaglandin E synthase 0.914727
PLA2G1B phospholipase A2, group IB (pancreas) 0.897051
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.885569
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.882701
ICAM1 intercellular adhesion molecule 1 0.864274
TADA1 transcriptional adaptor 1 0.846259
MEFV Mediterranean fever 0.824948
APLF aprataxin and PNKP like factor 0.796232
F2RL3 coagulation factor II (thrombin) receptor-like 3 0.77207
PGP phosphoglycolate phosphatase 0.744766
IL2 interleukin 2 0.741111
TAC1 tachykinin, precursor 1 0.696306
GRAP GRB2-related adaptor protein 0.687891
CCL11 chemokine (C-C motif) ligand 11 0.686291
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.681495
PDE4A phosphodiesterase 4A, cAMP-specific 0.679898
PGF placental growth factor 0.669936
IL17A interleukin 17A 0.66914
TACR3 tachykinin receptor 3 0.638282
NOS2 nitric oxide synthase 2, inducible 0.634349
ALB albumin 0.621792
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.60342
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.59874
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.593674
FAT3 FAT atypical cadherin 3 0.588612
TBP TATA box binding protein 0.581996
C1QC complement component 1, q subcomponent, C chain 0.573439
FASLG Fas ligand (TNF superfamily, member 6) 0.57305
AGR3 anterior gradient 3 0.562169
PYCR1 pyrroline-5-carboxylate reductase 1 0.549359
SOD2 superoxide dismutase 2, mitochondrial 0.536183
LYZ lysozyme 0.52536
CXCL8 chemokine (C-X-C motif) ligand 8 0.516494
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.510728
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.501527
CD4 CD4 molecule 0.500761
IL6 interleukin 6 0.489311
ANXA1 annexin A1 0.48893
CCL5 chemokine (C-C motif) ligand 5 0.488169
POMC proopiomelanocortin 0.46655
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.46466
PRAMEF6 PRAME family member 6 0.463149
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.460883
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.457487
CRP C-reactive protein, pentraxin-related 0.450324
PPAT phosphoribosyl pyrophosphate amidotransferase 0.434524
ENO2 enolase 2 (gamma, neuronal) 0.430768
HAGH hydroxyacylglutathione hydrolase 0.42364
IL5 interleukin 5 0.413527
PARP1 poly (ADP-ribose) polymerase 1 0.397098
C5AR1 complement component 5a receptor 1 0.393374
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.390025
IL10 interleukin 10 0.382966
TSC22D3 TSC22 domain family, member 3 0.372587
HRH4 histamine receptor H4 0.371847
PLA2G2D phospholipase A2, group IID 0.355604
NDEL1 nudE neurodevelopment protein 1-like 1 0.342372
DPEP1 dipeptidase 1 (renal) 0.341639
HSF1 heat shock transcription factor 1 0.338707
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.338341
C1QB complement component 1, q subcomponent, B chain 0.335412
PPARA peroxisome proliferator-activated receptor alpha 0.32701
HIF3A hypoxia inducible factor 3, alpha subunit 0.316092
SELL selectin L 0.313552
CD1B CD1b molecule 0.301254
PATE1 prostate and testis expressed 1 0.300533
CCL25 chemokine (C-C motif) ligand 25 0.299092
C1QA complement component 1, q subcomponent, A chain 0.297651
CLCN6 chloride channel, voltage-sensitive 6 0.296931
CP ceruloplasmin (ferroxidase) 0.287593
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.278297
HIST2H2AC histone cluster 2, H2ac 0.276514
HIST2H2AA4 histone cluster 2, H2aa4 0.276158
HIST2H2AA3 histone cluster 2, H2aa3 0.276158
EPX eosinophil peroxidase 0.273308
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.270819
HRH1 histamine receptor H1 0.260891
ELANE elastase, neutrophil expressed 0.25207
KEL Kell blood group, metallo-endopeptidase 0.246448
MSLN mesothelin 0.243645
CD79A CD79a molecule, immunoglobulin-associated alpha 0.231102
PTAFR platelet-activating factor receptor 0.229716
DUT deoxyuridine triphosphatase 0.227297
GUSB glucuronidase, beta 0.226262
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.222822
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.222822
TGFB1 transforming growth factor, beta 1 0.221108
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.220081
BAX BCL2-associated X protein 0.21974
CCR3 chemokine (C-C motif) receptor 3 0.206913
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.203604
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.192031
C5 complement component 5 0.189244
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.187113
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.184128
AZU1 azurocidin 1 0.18151
CFI complement factor I 0.178126
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.169571
GYPA glycophorin A (MNS blood group) 0.163317
IL12B interleukin 12B 0.161912
FPR1 formyl peptide receptor 1 0.157929