| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the podophyllotoxin-5841 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACAN | aggrecan |
| ADCY6 | adenylate cyclase 6 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCDC93 | coiled-coil domain containing 93 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK17 | cyclin-dependent kinase 17 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLDN1 | claudin 1 |
| CLTA | clathrin, light chain A |
| COL4A1 | collagen, type IV, alpha 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTGF | connective tissue growth factor |
| CTSF | cathepsin F |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCTN1 | dynactin 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DUSP1 | dual specificity phosphatase 1 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FGF5 | fibroblast growth factor 5 |
| FGL2 | fibrinogen-like 2 |
| FH | fumarate hydratase |
| FST | follistatin |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GSTA3 | glutathione S-transferase alpha 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTM1 | glutathione S-transferase mu 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HOXA4 | homeobox A4 |
| IL11 | interleukin 11 |
| IL18 | interleukin 18 |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL33R | interleukin 33 receptor |
| INHBA | inhibin, beta A |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| KRT34 | keratin 34, type I |
| LAMC3 | laminin, gamma 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MED25 | mediator complex subunit 25 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MST1 | macrophage stimulating 1 |
| MTM1 | myotubularin 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NRXN3 | neurexin 3 |
| PCDH11Y | protocadherin 11 Y-linked |
| PDLIM3 | PDZ and LIM domain 3 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PVR | poliovirus receptor |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNF146 | ring finger protein 146 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMAD7 | SMAD family member 7 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TAGLN3 | transgelin 3 |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TGFB2 | transforming growth factor, beta 2 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UNC13A | unc-13 homolog A (C. elegans) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WWC1 | WW and C2 domain containing 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF318 | zinc finger protein 318 |
| ZNF337 | zinc finger protein 337 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CENPO | centromere protein O |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| DDN | dendrin |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EN1 | engrailed homeobox 1 |
| EVPL | envoplakin |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FCHO1 | FCH domain only 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXA1 | forkhead box A1 |
| FPGS | folylpolyglutamate synthase |
| GLCE | glucuronic acid epimerase |
| GPATCH1 | G patch domain containing 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AM | histone cluster 1, H2am |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA11 | homeobox A11 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT54 | intraflagellar transport 54 |
| IGFLR1 | IGF-like family receptor 1 |
| IL17RB | interleukin 17 receptor B |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LAMB2 | laminin, beta 2 (laminin S) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTC4S | leukotriene C4 synthase |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MB | myoglobin |
| MICALL2 | MICAL-like 2 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOL12 | nucleolar protein 12 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORC1 | origin recognition complex, subunit 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PDE12 | phosphodiesterase 12 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PRPH | peripherin |
| PRR15L | proline rich 15-like |
| PTGFR | prostaglandin F receptor (FP) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNTA1 | syntrophin, alpha 1 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TESK2 | testis-specific kinase 2 |
| TGFB3 | transforming growth factor, beta 3 |
| TLN1 | talin 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM187 | transmembrane protein 187 |
| TRABD | TraB domain containing |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN8 | tetraspanin 8 |
| TTI2 | TELO2 interacting protein 2 |
| TUBA1A | tubulin, alpha 1a |
| TUBA3D | tubulin, alpha 3d |
| TUBA4A | tubulin, alpha 4a |
| TUBB | tubulin, beta class I |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF385D | zinc finger protein 385D |
| ZNF446 | zinc finger protein 446 |
| ZNF528 | zinc finger protein 528 |
| ZNF692 | zinc finger protein 692 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF787 | zinc finger protein 787 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
