| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the podophyllotoxin-6103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABHD8 | abhydrolase domain containing 8 |
| ADD2 | adducin 2 (beta) |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| ATG10 | autophagy related 10 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BEST2 | bestrophin 2 |
| BGN | biglycan |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEP112 | centrosomal protein 112kDa |
| CLCN1 | chloride channel, voltage-sensitive 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DOCK3 | dedicator of cytokinesis 3 |
| DST | dystonin |
| EDN1 | endothelin 1 |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 |
| ETV1 | ets variant 1 |
| EXOC6B | exocyst complex component 6B |
| FCMR | Fc fragment of IgM receptor |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GK3P | glycerol kinase 3 pseudogene |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR161 | G protein-coupled receptor 161 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSN | gelsolin |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAL | histidine ammonia-lyase |
| HDAC6 | histone deacetylase 6 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HFE | hemochromatosis |
| HOXA1 | homeobox A1 |
| HPSE2 | heparanase 2 (inactive) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KLHL18 | kelch-like family member 18 |
| LEFTY2 | left-right determination factor 2 |
| LOC157562 | uncharacterized LOC157562 |
| LOC399491 | |
| LPIN1 | lipin 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY9 | lymphocyte antigen 9 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRL | neural retina leucine zipper |
| OBSL1 | obscurin-like 1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PODNL1 | podocan-like 1 |
| POF1B | premature ovarian failure, 1B |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RTN2 | reticulon 2 |
| RUNX1 | runt-related transcription factor 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| S100A11 | S100 calcium binding protein A11 |
| SAA3P | serum amyloid A3 pseudogene |
| SLC39A9 | solute carrier family 39, member 9 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TGFB2 | transforming growth factor, beta 2 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPPP | tubulin polymerization promoting protein |
| TSC2 | tuberous sclerosis 2 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| YIPF4 | Yip1 domain family, member 4 |
| ZFPL1 | zinc finger protein-like 1 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AMPH | amphiphysin |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AUTS2 | autism susceptibility candidate 2 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMP10 | bone morphogenetic protein 10 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CRYGC | crystallin, gamma C |
| CUL9 | cullin 9 |
| CXORF56 | chromosome X open reading frame 56 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMPR | guanosine monophosphate reductase |
| GPR21 | G protein-coupled receptor 21 |
| GRPR | gastrin-releasing peptide receptor |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BC | histone cluster 1, H2bc |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXA4 | homeobox A4 |
| HOXD11 | homeobox D11 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0125 | KIAA0125 |
| KIAA1456 | KIAA1456 |
| KIF13A | kinesin family member 13A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LHX1 | LIM homeobox 1 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MMP2 | matrix metallopeptidase 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| NPTX1 | neuronal pentraxin I |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OLFML2A | olfactomedin-like 2A |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDH12 | protocadherin 12 |
| PCDHA6 | protocadherin alpha 6 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PICK1 | protein interacting with PRKCA 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFXAP | regulatory factor X-associated protein |
| RLN1 | relaxin 1 |
| RPL10L | ribosomal protein L10-like |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TRAIP | TRAF interacting protein |
| VEGFB | vascular endothelial growth factor B |
| WDR76 | WD repeat domain 76 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XYLT1 | xylosyltransferase I |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF747 | zinc finger protein 747 |
