| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the podophyllotoxin-7198 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| AEN | apoptosis enhancing nuclease |
| AFAP1 | actin filament associated protein 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANTXR1 | anthrax toxin receptor 1 |
| AREG | amphiregulin |
| ASTN2 | astrotactin 2 |
| ATF3 | activating transcription factor 3 |
| ATXN1 | ataxin 1 |
| ATXN3 | ataxin 3 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CLDN1 | claudin 1 |
| COPS8 | COP9 signalosome subunit 8 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR3 | early growth response 3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| F11R | F11 receptor |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM65A | family with sequence similarity 65, member A |
| FBRS | fibrosin |
| FERMT2 | fermitin family member 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLS | glutaminase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRB10 | growth factor receptor-bound protein 10 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H1E | histone cluster 1, H1e |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IDS | iduronate 2-sulfatase |
| INSIG1 | insulin induced gene 1 |
| ITCH | itchy E3 ubiquitin protein ligase |
| ITGB6 | integrin, beta 6 |
| JUN | jun proto-oncogene |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| LDLR | low density lipoprotein receptor |
| LOC399491 | |
| LPIN1 | lipin 1 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MGLL | monoglyceride lipase |
| MINK1 | misshapen-like kinase 1 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NRSN2 | neurensin 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| QKI | QKI, KH domain containing, RNA binding |
| RARG | retinoic acid receptor, gamma |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCAN1 | regulator of calcineurin 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SMAD3 | SMAD family member 3 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPAG8 | sperm associated antigen 8 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| SRI | sorcin |
| STK4 | serine/threonine kinase 4 |
| SYNGR3 | synaptogyrin 3 |
| TGFB2 | transforming growth factor, beta 2 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPM1 | tropomyosin 1 (alpha) |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TTC28 | tetratricopeptide repeat domain 28 |
| USP34 | ubiquitin specific peptidase 34 |
| VEGFA | vascular endothelial growth factor A |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC7 | armadillo repeat containing 7 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEP97 | centrosomal protein 97kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CST6 | cystatin E/M |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEAF1 | DEAF1 transcription factor |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DSPP | dentin sialophosphoprotein |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM53B | family with sequence similarity 53, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FGF23 | fibroblast growth factor 23 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GPC3 | glypican 3 |
| HIST1H2AC | histone cluster 1, H2ac |
| IL17RA | interleukin 17 receptor A |
| IRF9 | interferon regulatory factor 9 |
| IRX4 | iroquois homeobox 4 |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0125 | KIAA0125 |
| KIAA0319L | KIAA0319-like |
| KIZ | kizuna centrosomal protein |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MED9 | mediator complex subunit 9 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTRF1 | mitochondrial translational release factor 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PICK1 | protein interacting with PRKCA 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| PRMT7 | protein arginine methyltransferase 7 |
| PROL1 | proline rich, lacrimal 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCAMP5 | secretory carrier membrane protein 5 |
| SDC3 | syndecan 3 |
| SESN1 | sestrin 1 |
| SETD1A | SET domain containing 1A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC41A3 | solute carrier family 41, member 3 |
| SPATA7 | spermatogenesis associated 7 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TBX19 | T-box 19 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIGD6 | tigger transposable element derived 6 |
| TLR5 | toll-like receptor 5 |
| TMC5 | transmembrane channel-like 5 |
| TMEM184C | transmembrane protein 184C |
| TRAF2 | TNF receptor-associated factor 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBB | tubulin, beta class I |
| TUBB4B | tubulin, beta 4B class IVb |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VASH1 | vasohibin 1 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR19 | WD repeat domain 19 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF205 | zinc finger protein 205 |
| ZNF428 | zinc finger protein 428 |
| ZNF767P | zinc finger family member 767, pseudogene |
