podosome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. (Gene Ontology, GO_0002102)
External Link http://amigo.geneontology.org/amigo/term/GO:0002102
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Genes

22 proteins localized to the podosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM8 ADAM metallopeptidase domain 8
AFAP1L1 actin filament associated protein 1-like 1
BIN2 bridging integrator 2
CTTN cortactin
DBNL drebrin-like
FERMT3 fermitin family member 3
GSN gelsolin
HNRNPK heterogeneous nuclear ribonucleoprotein K
KIF9 kinesin family member 9
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LPXN leupaxin
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RHOU ras homolog family member U
SH3GL1 SH3-domain GRB2-like 1
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SVIL supervillin
TPM3 tropomyosin 3
TPM4 tropomyosin 4
VCAM1 vascular cell adhesion molecule 1
WDR1 WD repeat domain 1