podosome Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. (Gene Ontology, GO_0002102)
External Link http://amigo.geneontology.org/amigo/term/GO:0002102
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Genes

21 proteins localized to the podosome cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AMOTL2 angiomotin like 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BIN2 bridging integrator 2
DBNL drebrin-like
ERC1 ELKS/RAB6-interacting/CAST family member 1
FERMT3 fermitin family member 3
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FSCN1 fascin actin-bundling protein 1
GSN gelsolin
KIF9 kinesin family member 9
LPXN leupaxin
PHLDB2 pleckstrin homology-like domain, family B, member 2
PLEC plectin
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SPATA13 spermatogenesis associated 13
TOX4 TOX high mobility group box family member 4
VCAM1 vascular cell adhesion molecule 1