pole Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description polymerase (DNA directed), epsilon, catalytic subunit|This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 5426)
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Genes

36 genes co-occuring with the biological term pole in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
AURKB aurora kinase B
BUB3 BUB3 mitotic checkpoint protein
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CCR2 chemokine (C-C motif) receptor 2
CENPE centromere protein E, 312kDa
CEP57 centrosomal protein 57kDa
CHM choroideremia (Rab escort protein 1)
CKAP5 cytoskeleton associated protein 5
DAOA D-amino acid oxidase activator
EZR ezrin
FAM3D family with sequence similarity 3, member D
KIF15 kinesin family member 15
KIF2A kinesin heavy chain member 2A
KIF2C kinesin family member 2C
KPNB1 karyopherin (importin) beta 1
LIMK1 LIM domain kinase 1
MAP9 microtubule-associated protein 9
MYO1B myosin IB
NDC80 NDC80 kinetochore complex component
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NIN ninein (GSK3B interacting protein)
PF4 platelet factor 4
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLK1 polo-like kinase 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
RCC1 regulator of chromosome condensation 1
SCP2 sterol carrier protein 2
SMC1A structural maintenance of chromosomes 1A
SPAG5 sperm associated antigen 5
SSFA2 sperm specific antigen 2
TJP1 tight junction protein 1
TPX2 TPX2, microtubule-associated
TRA T cell receptor alpha locus