polycythemia vera Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

180 genes co-occuring with the disease polycythemia vera in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
JAK2 Janus kinase 2 3.26342
CD177 CD177 molecule 2.09476
MPL MPL proto-oncogene, thrombopoietin receptor 1.78173
EPOR erythropoietin receptor 1.71408
TET2 tet methylcytosine dioxygenase 2 1.68997
JAK1 Janus kinase 1 1.56045
EPO erythropoietin 1.54407
THPO thrombopoietin 1.47945
CD34 CD34 molecule 1.41797
ASXL1 additional sex combs like transcriptional regulator 1 1.38123
IL3 interleukin 3 1.19834
FIP1L1 factor interacting with PAPOLA and CPSF1 1.17593
TYK2 tyrosine kinase 2 1.16478
SH2B3 SH2B adaptor protein 3 1.1541
NFE2 nuclear factor, erythroid 2 1.10468
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.06228
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.05597
CALR calreticulin 1.03282
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.01596
JAK3 Janus kinase 3 1.01047
BCR breakpoint cluster region 0.977165
IFNA1 interferon, alpha 1 0.923387
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.915551
F5 coagulation factor V (proaccelerin, labile factor) 0.915551
ALPPL2 alkaline phosphatase, placental-like 2 0.911433
ALPP alkaline phosphatase, placental 0.911022
ALPL alkaline phosphatase, liver/bone/kidney 0.910199
G6PD glucose-6-phosphate dehydrogenase 0.879014
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.865912
BCAM basal cell adhesion molecule (Lutheran blood group) 0.850764
IFNA2 interferon, alpha 2 0.842573
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.827409
KIAA0355 KIAA0355 0.825768
SETD2 SET domain containing 2 0.812232
IGLV1-47 immunoglobulin lambda variable 1-47 0.805667
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.786394
FGFR1 fibroblast growth factor receptor 1 0.78066
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.762271
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.746798
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.724098
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.722077
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.712392
PROS1 protein S (alpha) 0.709572
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.708364
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.704742
SOX30 SRY (sex determining region Y)-box 30 0.701526
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.689893
SOCS3 suppressor of cytokine signaling 3 0.674315
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.665166
VWF von Willebrand factor 0.642221
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.639463
GPX8 glutathione peroxidase 8 (putative) 0.638676
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.634349
BCL2L1 BCL2-like 1 0.634349
PF4 platelet factor 4 0.622575
SOCS2 suppressor of cytokine signaling 2 0.60225
NAAA N-acylethanolamine acid amidase 0.594843
THBD thrombomodulin 0.591337
ACSL6 acyl-CoA synthetase long-chain family member 6 0.590169
ELN elastin 0.582773
SETD1B SET domain containing 1B 0.581606
SPPL2B signal peptide peptidase like 2B 0.567609
VAV1 vav 1 guanine nucleotide exchange factor 0.5645
CARD6 caspase recruitment domain family, member 6 0.55945
LUZP6 leucine zipper protein 6 0.556344
RARS arginyl-tRNA synthetase 0.547032
ZNF77 zinc finger protein 77 0.543155
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.540829
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.540055
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.523816
MTPAP mitochondrial poly(A) polymerase 0.513417
HMGA2 high mobility group AT-hook 2 0.509192
ETV6 ets variant 6 0.508424
FLT3 fms-related tyrosine kinase 3 0.501909
F2 coagulation factor II (thrombin) 0.495411
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.483985
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.483224
F3 coagulation factor III (thromboplastin, tissue factor) 0.481705
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.480186
CD63 CD63 molecule 0.479807
DEFA4 defensin, alpha 4, corticostatin 0.474877
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.462772
KLF1 Kruppel-like factor 1 (erythroid) 0.459751
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.451831
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.451078
GARS glycyl-tRNA synthetase 0.450324
FTL ferritin, light polypeptide 0.445805
FTH1 ferritin, heavy polypeptide 1 0.445429
MIR190A microRNA 190a 0.440162
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.43941
PGK1 phosphoglycerate kinase 1 0.42364
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.423265
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.420641
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.418768
GYPC glycophorin C (Gerbich blood group) 0.41727
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.416521
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.415024
TSGA10 testis specific, 10 0.401945
PTPRR protein tyrosine phosphatase, receptor type, R 0.394863
IGF1 insulin-like growth factor 1 (somatomedin C) 0.390397
GBP2 guanylate binding protein 2, interferon-inducible 0.390025
TCN2 transcobalamin II 0.383708
IRAK2 interleukin-1 receptor-associated kinase 2 0.379997
NF1 neurofibromin 1 0.379256
SSBP2 single-stranded DNA binding protein 2 0.377773
ZFPM1 zinc finger protein, FOG family member 1 0.372958
S100A10 S100 calcium binding protein A10 0.360395
RUNX1 runt-related transcription factor 1 0.353763
GAS2 growth arrest-specific 2 0.345675
HBB hemoglobin, beta 0.344574
HRAS Harvey rat sarcoma viral oncogene homolog 0.343473
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.342372
KANK1 KN motif and ankyrin repeat domains 1 0.336144
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.330295
NEU4 sialidase 4 0.328834
RAB4A RAB4A, member RAS oncogene family 0.321181
MMRN1 multimerin 1 0.312102
JARID2 jumonji, AT rich interactive domain 2 0.311014
PTH parathyroid hormone 0.308842
FPR1 formyl peptide receptor 1 0.30631
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.301615
HAMP hepcidin antimicrobial peptide 0.301615
HAUS3 HAUS augmin-like complex, subunit 3 0.300173
RNF19B ring finger protein 19B 0.299092
CD164 CD164 molecule, sialomucin 0.297291
MATK megakaryocyte-associated tyrosine kinase 0.295492
SCARB2 scavenger receptor class B, member 2 0.290821
SRSF2 serine/arginine-rich splicing factor 2 0.287593
MPST mercaptopyruvate sulfurtransferase 0.285802
LAMA5 laminin, alpha 5 0.284013
BMP10 bone morphogenetic protein 10 0.280082
CD36 CD36 molecule (thrombospondin receptor) 0.276158
CD59 CD59 molecule, complement regulatory protein 0.265849
AGO2 argonaute RISC catalytic component 2 0.253479
IGFBP1 insulin-like growth factor binding protein 1 0.253479
NFIB nuclear factor I/B 0.251366
SPRY4 sprouty homolog 4 (Drosophila) 0.251015
FEN1 flap structure-specific endonuclease 1 0.249608
ANXA5 annexin A5 0.240847
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.240148
RXRB retinoid X receptor, beta 0.239101
SCARB1 scavenger receptor class B, member 1 0.237706
MAPK14 mitogen-activated protein kinase 14 0.233878
PNN pinin, desmosome associated protein 0.233878
PFKM phosphofructokinase, muscle 0.231795
PRM2 protamine 2 0.216672
LMO2 LIM domain only 2 (rhombotin-like 1) 0.216332
EGLN1 egl-9 family hypoxia-inducible factor 1 0.211261
NUP98 nucleoporin 98kDa 0.211261
MIR26B microRNA 26b 0.210925
CHRD chordin 0.210925
SCN2A sodium channel, voltage gated, type II alpha subunit 0.207912
ADGRG1 adhesion G protein-coupled receptor G1 0.205916
LIN9 lin-9 DREAM MuvB core complex component 0.205585
PGM1 phosphoglucomutase 1 0.204263
GRB2 growth factor receptor-bound protein 2 0.203604
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.202618
F12 coagulation factor XII (Hageman factor) 0.201635
IGHA1 immunoglobulin heavy constant alpha 1 0.201635
CLEC11A C-type lectin domain family 11, member A 0.199356
BMP8B bone morphogenetic protein 8b 0.199033
BMPR1B bone morphogenetic protein receptor, type IB 0.198064
HDAC6 histone deacetylase 6 0.194232
HDAC9 histone deacetylase 9 0.193915
CYGB cytoglobin 0.191097
IFI27 interferon, alpha-inducible protein 27 0.187415
RBM15 RNA binding motif protein 15 0.184128
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.181222
BRD2 bromodomain containing 2 0.179802
E2F6 E2F transcription factor 6 0.178682
BMP3 bone morphogenetic protein 3 0.176215
OLFM4 olfactomedin 4 0.176215
MBD1 methyl-CpG binding domain protein 1 0.173832
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.171535
SPRY2 sprouty homolog 2 (Drosophila) 0.168854
GSR glutathione reductase 0.167915
TP53 tumor protein p53 0.166768
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.162707
STAT1 signal transducer and activator of transcription 1, 91kDa 0.161331
HDAC11 histone deacetylase 11 0.160021