polydactyly Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000562
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Genes

90 gene mutations causing the polydactyly phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ALX4 ALX homeobox 4
B9D1 B9 protein domain 1
BCLAF1 BCL2-associated transcription factor 1
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
C2CD3 C2 calcium-dependent domain containing 3
C5ORF42 chromosome 5 open reading frame 42
CC2D2A coiled-coil and C2 domain containing 2A
CENPJ centromere protein J
CRABP2 cellular retinoic acid binding protein 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPH1 diphthamide biosynthesis 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDA ectodysplasin A
EFNB1 ephrin-B1
EIF3C eukaryotic translation initiation factor 3, subunit C
EN1 engrailed homeobox 1
ETV5 ets variant 5
FIGN fidgetin
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
FREM2 FRAS1 related extracellular matrix protein 2
FUZ fuzzy planar cell polarity protein
GLCE glucuronic acid epimerase
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPC3 glypican 3
GRIP1 glutamate receptor interacting protein 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXD13 homeobox D13
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSPB11 heat shock protein family B (small), member 11
IFT122 intraflagellar transport 122
IFT140 intraflagellar transport 140
IFT172 intraflagellar transport 172
IFT54 intraflagellar transport 54
IFT57 intraflagellar transport 57
IFT80 intraflagellar transport 80
IFT88 intraflagellar transport 88
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INTU inturned planar cell polarity protein
KIF3A kinesin family member 3A
KIF7 kinesin family member 7
KIFAP3 kinesin-associated protein 3
LRP4 low density lipoprotein receptor-related protein 4
LRP6 low density lipoprotein receptor-related protein 6
MBD4 methyl-CpG binding domain protein 4
MECOM MDS1 and EVI1 complex locus
MEGF8 multiple EGF-like-domains 8
MKS1 Meckel syndrome, type 1
PAX1 paired box 1
PAX9 paired box 9
PC pyruvate carboxylase
PCSK5 proprotein convertase subtilisin/kexin type 5
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTCH1 patched 1
PTK7 protein tyrosine kinase 7 (inactive)
RAB23 RAB23, member RAS oncogene family
RECQL4 RecQ protein-like 4
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPGRIP1L RPGRIP1-like
RPL24 ribosomal protein L24
RPL38 ribosomal protein L38
SC5D sterol-C5-desaturase
SDCCAG8 serologically defined colon cancer antigen 8
SFRP2 secreted frizzled-related protein 2
SHH sonic hedgehog
SKI SKI proto-oncogene
SPRY4 sprouty homolog 4 (Drosophila)
TBC1D32 TBC1 domain family, member 32
TBX2 T-box 2
TCTN1 tectonic family member 1
TCTN2 tectonic family member 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TMEM107 transmembrane protein 107
TMEM231 transmembrane protein 231
TTC21B tetratricopeptide repeat domain 21B
TULP3 tubby like protein 3
TWIST1 twist family bHLH transcription factor 1
WDPCP WD repeat containing planar cell polarity effector
WDR19 WD repeat domain 19
WDR35 WD repeat domain 35
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB16 zinc finger and BTB domain containing 16